Food Frontiers, Volume 5, Issue 3, Page 1145-1165, May 2024.This review provides an in‐depth exploration of nineteen types of food‐derived bioactive peptides, focusing on their intricate interplay and foundational functionalities, particularly antioxidant actions, in relation to human health. It emphasizes the complex yet crucial mechanisms of these peptides in various bodily systems and underscores the ...
Tiantian Zhao +8 more
wiley +1 more source
Psychedelics Promote Structural and Functional Neural Plasticity. [PDF]
, 2018 Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of depression and related disorders. The ability to promote both structural and functional plasticity in the PFC has been hypothesized to underlie the fast ...
Barragan, Eden V +15 more
core +2 more sources
Effect of anti‐CGRP‐targeted therapy on migraine aura: Results of an observational case series study
CNS Neuroscience &Therapeutics, Volume 30, Issue 2, February 2024.This observational study involving a series of migraine patients affected by both migraine with and without aura reveals that anti‐CGRP antibodies induced a significant decrease in headache frequency of migraine without aura but not of migraine with aura attacks.
Elena Cresta +4 more
wiley +1 more source
Combining Cox Regressions Across a Heterogeneous Distributed Research Network Facing Small and Zero Counts [PDF]
arXiv, 2021 Studies of the effects of medical interventions increasingly take place in distributed research settings using data from multiple clinical data sources including electronic health records and administrative claims. In such settings, privacy concerns typically prohibit sharing of individual patient data, and instead, analyses can only utilize summary ...
arxiv
Antidepressant Treatment Of Major Depressive Disorder In Patients With Comorbid Alcohol Use Disorder: Two Meta-Analyses Of Randomized Placebo-Controlled Trials [PDF]
, 2020 Objective: Aim 1: To examine the efficacy of antidepressant agents compared with placebo in reducing depressive symptoms in subjects with comorbid Alcohol Use Disorders (AUD).
Johnson, Isaac Nathan Smullin
core +1 more source
The Predominant Protective Effect of Tianeptine Over Other Antidepressants in Models of Neuronal Apoptosis: The Effect Blocked by Inhibitors of MAPK/ERK1/2 and PI3-K/Akt Pathways [PDF]
, 2013 Tianeptine (Tian) possesses neuroprotective potential, however, little is known about the effect of this drug in models of neuronal apoptosis. In the present study, we aimed (1) to compare the neuroprotective capacities of some antidepressants (ADs) in ...
D. Jantas, S. Krawczyk, W. Lason
core +1 more source
Anxiolytic and Antidepressant Effect of Phaseolus vulgaris on Animal Models
Scientifica, Volume 2024, Issue 1, 2024.An experimental study was conducted using rodents at different doses to evaluate the effect of Phaseolus vulgaris (red beans) on cage crossing, head dip, open field, elevated plus maze, and light and dark apparatus for anxiety and forced swim test for depression.
Rabia Munawwar +6 more
wiley +1 more source
More green space is related to less antidepressant prescription rates in the Netherlands: A Bayesian geoadditive quantile regression approach [PDF]
Environmental Research 2018, 2018 Exposure to green space seems to be beneficial for self-reported mental health. In this study we used an objective health indicator, namely antidepressant prescription rates. Current studies rely exclusively upon mean regression models assuming linear associations.
arxiv
Multiply robust estimators in longitudinal studies with missing data under control-based imputation [PDF]
arXiv, 2021 Longitudinal studies are often subject to missing data. The ICH E9(R1) addendum addresses the importance of defining a treatment effect estimand with the consideration of intercurrent events. Jump-to-reference (J2R) is one classically envisioned control-based scenario for the treatment effect evaluation using the hypothetical strategy, where the ...
arxiv
SERTRALINE AND MIRTAZAPINE AS GERIATRIC ANTIDEPRESSANTS [PDF]
, 2013 Background: Depression within the geriatric patient population is an important issue as it is associated with increased mortality. Such depression may have a different aetiology to that in younger patients and be associated with comorbid chronic physical
Bhogle, Madhavi, Holland, Jonathon
core +1 more source