Clinical features of children with drug poisoning in a single emergency department in Goyang, Korea [PDF]
Purpose Pediatric drug poisoning is a frequent reason for emergency department (ED) visits. Considering the increasing number of mental illnesses in adolescents, it has become a serious public health problem. We aimed to investigate the drug poisoning in
Jung Min Park
doaj +1 more source
Translational Informatics for Natural Products as Antidepressant Agents [PDF]
Depression, a neurological disorder, is a universally common and debilitating illness where social and economic issues could also become one of its etiologic factors. From a global perspective, it is the fourth leading cause of long-term disability in human beings.
Rajeev K. Singla+5 more
openaire +3 more sources
A dose-effect network meta-analysis model: an application in antidepressants [PDF]
Network meta-analysis (NMA) has been used to answer a range of clinical questions about the preferable intervention for a given condition. Although the effectiveness and safety of pharmacological agents depend on the dose administered, NMA applications typically ignore the role that drugs dosage play on the results.
arxiv +1 more source
TPH1A218C polymorphism and temperament in major depression [PDF]
BACKGROUND: In major depression, one of the candidate genes possibly affecting the risk and severity of symptoms has been found to be tryptophan hydroxylase (TPH1).
A Illi+29 more
core +4 more sources
Licorice (glycyrrhiza glabra) extracts-suitable pharmacological interventions for covid-19? a review [PDF]
Even though vaccination has started against COVID-19, people should continue maintaining personal and social caution as it takes months or years to get everyone vaccinated, and we are not sure how long the vaccine remains efficacious.
Abraham, Joji, Florentine, Singarayer
core +2 more sources
Los placebos, el dolor neuropàtico y de género
INTRODUCTION: the placebos' analgesic effect seems to depend on different factors such as socio-cultural, psychological and genetic aspects. The effects of gender on placebos' analgesic response have rarely been documented in clinical studies, even ...
Carlos B. Moreno+1 more
doaj +2 more sources
Severe hyponatremia and the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with fluoxetine: case report [PDF]
Hyponatremia is a significant complication of treatment with serotonin selective reuptake inhibitors (SSRI). We describe a case of a 53-year-old woman that was started on fluoxetine 20 mg/day for depression.
Carlos Alexandre Twardowschy+3 more
doaj +1 more source
Antidepressive and anxiolytic effects of ostruthin, a TREK-1 channel activator [PDF]
We screened a library of botanical compounds purified from plants of Vietnam for modulators of the activity of a two-pore domain K+ channel, TREK-1, and we identified a hydroxycoumarin-related compound, ostruthin, as an activator of this channel ...
Joseph, Ancy+3 more
core +2 more sources
Antidepressive Effectiveness of Amisulpride, Aripiprazole, and Olanzapine in Patients with Schizophrenia Spectrum Disorders: A Secondary Outcome Analysis of a Pragmatic, Randomized Trial (BeSt InTro) [PDF]
Background Depressive symptoms are frequent in schizophrenia and associated with a poorer outcome. Currently, the optimal treatment for depressive symptoms in schizophrenia remains undetermined.
Alisauskiene, Renata+14 more
core +3 more sources
General practitioners' conceptions about treatment of depression and factors that may influence their practice in this area. A postal survey [PDF]
BACKGROUND: The way GPs work does not appear to be adapted to the needs of depressive patients. Therefore we wanted to examine Swedish GPs' conceptions of depressive disorders and their treatment and GPs' ideas of factors that may influence their manner ...
A Cartwright+49 more
core +3 more sources