Post-stroke depression modulation and in vivo antioxidant activity of gallic acid and its synthetic derivatives in a murine model system [PDF]
Gallic acid (3,4,5-trihydroxybenzoic acid, GA) is a plant secondary metabolite, which shows antioxidant activity and is commonly found in many plant-based foods and beverages.
Antoni Sureda +9 more
core +2 more sources
Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor [PDF]
In the 1980s particular endogenous metabolites of progesterone and of deoxycorticosterone were revealed to be potent, efficacious, positive allosteric modulators (PAMs) of the GABAA receptor (GABAAR).
Belelli, Delia +3 more
core +1 more source
“Caring for Junior” - A Problem-Based Learning Case
Introduction Epidemiological studies suggest that as many as 45% of adults 85 years or older have cognitive impairment. To help prepare our first-year medical students to work with this population, we created this problem-based learning case. Methods The
Jonathan Flacker, Theodore Johnson
doaj +1 more source
Antidepressant Use and the Risk of Mood Instability
N/a.
Tomás Teodoro
doaj +1 more source
Evaluation of Overactive Bladder in Male Antidepressant Users: A Prospective Study [PDF]
Purpose In this study, we investigated overactive bladder (OAB) functions in male patients who used antidepressant drugs (ADs) that were previously examined in female patients, based on conflicting data in literature regarding the effects of AD on OAB ...
Volkan Solmaz +6 more
doaj +1 more source
Anesthetic Considerations for Patients on Psychotropic Drug Therapies
Psychotropic drugs are used in the treatment of psychiatric and non-psychiatric conditions. Many patients who are on psychotropic medications may present for procedures requiring anesthesia.
Monica W. Harbell +5 more
doaj +1 more source
Latent classes of nonresponders, rapid responders, and gradual responders in depressed outpatients receiving antidepressant medication and psychotherapy [PDF]
BackgroundWe used growth mixture modeling (GMM) to identify subsets of patients with qualitatively distinct symptom trajectories resulting from treatment. Existing studies have focused on 12-week antidepressant trials.
Bagby, Michael +5 more
core +2 more sources
Hypertension and depression Hipertensão arterial sistêmica e depressão
Despite the high prevalence of depression and hypertension, the relationship between the two diseases has received little attention. This paper reviews the epidemiological, pathophysiological, and prognostic aspects of this association, as well as its ...
Andréia Zavaloni Scalco +3 more
doaj +1 more source
Smoking and antidepressants pharmacokinetics: a systematic review [PDF]
Despite an increasingly recognized relationship between depression and smoking, little is known about how smoking influences antidepressant response and treatment outcomes.
Donato, H +3 more
core +1 more source
Medication exposure and predictors of first mood episode in offspring of parents with bipolar disorder: a prospective study [PDF]
Objectives: To prospectively investigate whether baseline clinical characteristics and medication exposure predict development of major depressive disorder or bipolar disorder in offspring of parents with bipolar disorder. Methods: Youth aged 9-20 years
Fabiano G. Nery +8 more
doaj +1 more source

