Results 51 to 60 of about 16,532 (225)
Oman Medical Journal, 2023 Objectives: This study sought to determine the confidence level of mental health practitioners in Oman regarding the use of antidepressants during pregnancy and breastfeeding, assess their knowledge and need for further training in this area, and examine
Salim Al Kasbi +3 more
doaj +1 more source
Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)
Phytotherapy Research, EarlyView.ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley +1 more source
Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli +7 more
wiley +1 more source
PET studies of the serotonin system in major depression and its treatment [PDF]
, 2014 The serotonin system has been implicated in major depression since the 1960s, mainly based on the serotonin enhancing properties of antidepressants.
Tiger, Mikael
core +1 more source
British Journal of Pharmacology, Volume 183, Issue 12, Page 3340-3354, June 2026.Background and Purpose Ketamine consists of two enantiomers, (R)‐ketamine and (S)‐ketamine, which exhibit distinct pharmacological properties. Currently, only the (S)‐enantiomer has been approved for the treatment of major depressive disorder, whereas recent clinical studies have failed to demonstrate an antidepressant effect for (R)‐ketamine.
Szabolcs Koncz +4 more
wiley +1 more source
Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis [PDF]
, 2019 Inflammatory diseases of the gastrointestinal tract are emerging as a global problem with increased evidence and prevalence in numerous countries. A dysregulated sphingolipid metabolism occurs in patients with ulcerative colitis and is discussed to ...
Becker, Katrin A. +9 more
core +1 more source
Risk of gastrointestinal bleeding by specific SSRIs and SNRIs: A systematic review and meta‐analysis
British Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 793-808, March 2026.Aim The purpose of this study is to estimate the risk of gastrointestinal bleeding (GIB) by selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs) individual agents. Methods A systematic review was conducted for each unique antidepressant (i.e.
Ainhoa Gomez‐Lumbreras +8 more
wiley +1 more source
Efeitos da fluoxetina sobre a ultraestrutura mitocondrial no ventrículo direito de ratos expostos ao estresse pelo frio [PDF]
, 2009 OBJECTIVE: To assess fluoxetine effects on mitochondrial structure of the right ventricle in rats exposed to cold stress. METHODS: The experimental study procedures were performed in 250-300g male EPM-Wistar rats.
Abreu, Luiz Carlos de +7 more
core +4 more sources
Antidepresivos de nueva generación en neuropatía diabética dolorosa
Revista Ciencias de la Salud, 2011 The incidence of diabetic neuropathy increases with the duration of diabetes and the degree of hyperglycaemia. Pain is one of the mostcommon and incapacitating symptoms of diabetic neuropathy and itspharmacological control is complex.
Ángela M. Gutiérrez-Álvarez +1 more
doaj
The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes
Clinical Pharmacology &Therapeutics, Volume 119, Issue 3, Page 696-702, March 2026.Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali +4 more
wiley +1 more source