Results 51 to 60 of about 13,606 (212)

Potential Role of the Antidepressants Fluoxetine and Fluvoxamine in the Treatment of COVID-19 [PDF]

open access: yes, 2022
Mapping non-canonical cellular pathways affected by approved medications can accelerate drug repurposing efforts, which are crucial in situations with a global impact such as the COVID-19 pandemic.
Mohamed Mahdi   +7 more
core   +1 more source

Differential effects of ketamine enantiomers on EEG parameters including the gamma‐delta shift phenomenon

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 12, Page 3340-3354, June 2026.
Background and Purpose Ketamine consists of two enantiomers, (R)‐ketamine and (S)‐ketamine, which exhibit distinct pharmacological properties. Currently, only the (S)‐enantiomer has been approved for the treatment of major depressive disorder, whereas recent clinical studies have failed to demonstrate an antidepressant effect for (R)‐ketamine.
Szabolcs Koncz   +4 more
wiley   +1 more source

Risk of gastrointestinal bleeding by specific SSRIs and SNRIs: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 793-808, March 2026.
Aim The purpose of this study is to estimate the risk of gastrointestinal bleeding (GIB) by selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs) individual agents. Methods A systematic review was conducted for each unique antidepressant (i.e.
Ainhoa Gomez‐Lumbreras   +8 more
wiley   +1 more source

Use of Systemic Treatment in Patients with Chronic Pruritus: A Survey of Dermatologists in the Netherlands

open access: yesActa Dermato-Venereologica, 2019
Treatment of chronic pruritus can be a challenge for clinicians. Several systemic treatments have been suggested to reduce itch, such as gabapentinoids and antidepressants.
Tessa A. Kouwenhoven   +2 more
doaj   +1 more source

The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 3, Page 696-702, March 2026.
Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali   +4 more
wiley   +1 more source

Biochemical and Physiological Effects of Galanin in Health and Disease

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles   +3 more
wiley   +1 more source

Antidepressant-induced sexual dysfunction: A naturalistic study comparing sexual dysfunction among patients taking escitalopram, desvenlafaxine, and mirtazapine

open access: yesAnnals of Indian Psychiatry, 2021
Background: Antidepressant drugs are frequently associated with sexual dysfunction. Sexual side effects affect the patients' quality of life and in the long term and can lead to noncompliance and relapse.
Raj Kiran Donthu   +2 more
doaj   +1 more source

Cognitive training, alone and combined with acetylcholinesterase inhibitors, in neurocognitive disorders: long‐term efficacy and the role of cognitive reserve on 30 months of intervention

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.
Abstract INTRODUCTION Non‐pharmacological interventions are increasingly relevant in neurocognitive disorders (NCDs) management. Cognitive training (CT) may benefit early stages, when functional resources allow targeted stimulation. However, its long‐term effects and interaction with acetylcholinesterase inhibitors (AChEI) remain underexplored.
Adele Ravelli   +6 more
wiley   +1 more source

Antidepressive agents adverse effects [PDF]

open access: yes, 2013
Depresivni poremećaj predstavlja jednu od najjačih duševnih patnja. Osoba koja boluje od depresije duboko pati, sve njezine funkcije su promijenjene, ništa je ne veseli i nerijetko je suicidalna.
Kozumplik, Oliver   +4 more
core  

Overdoses with Tricyclic Antidepressants [PDF]

open access: yes, 1976
The authors present a 46-year-old female and a 14-month-old female following ingestion of an overdose of tricyclic antidepressants, amitriptyline and imipramine, respectively.
Judith A. Ludy   +4 more
core   +1 more source

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