Results 61 to 70 of about 16,532 (225)

Use of Systemic Treatment in Patients with Chronic Pruritus: A Survey of Dermatologists in the Netherlands

open access: yesActa Dermato-Venereologica, 2019
Treatment of chronic pruritus can be a challenge for clinicians. Several systemic treatments have been suggested to reduce itch, such as gabapentinoids and antidepressants.
Tessa A. Kouwenhoven   +2 more
doaj   +1 more source

Biochemical and Physiological Effects of Galanin in Health and Disease

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles   +3 more
wiley   +1 more source

Cognitive training, alone and combined with acetylcholinesterase inhibitors, in neurocognitive disorders: long‐term efficacy and the role of cognitive reserve on 30 months of intervention

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.
Abstract INTRODUCTION Non‐pharmacological interventions are increasingly relevant in neurocognitive disorders (NCDs) management. Cognitive training (CT) may benefit early stages, when functional resources allow targeted stimulation. However, its long‐term effects and interaction with acetylcholinesterase inhibitors (AChEI) remain underexplored.
Adele Ravelli   +6 more
wiley   +1 more source

Antidepressant-induced sexual dysfunction: A naturalistic study comparing sexual dysfunction among patients taking escitalopram, desvenlafaxine, and mirtazapine

open access: yesAnnals of Indian Psychiatry, 2021
Background: Antidepressant drugs are frequently associated with sexual dysfunction. Sexual side effects affect the patients' quality of life and in the long term and can lead to noncompliance and relapse.
Raj Kiran Donthu   +2 more
doaj   +1 more source

Alternanthera philoxeroides (Mart.) Griseb Mitigates Age‐Related Depression in Mice Through Regulation of Oxidative Stress and Neurogenic Mechanisms

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, Volume 2026, Issue 1, 2026.
Depression adversely impacts daily life, with age‐related neurodegeneration being a significant contributing factor. Neurodegenerative alterations, often accelerated by oxidative stress, underlie depressive progression in advanced age. Our previous research has reported that Alternanthera philoxeroides (Mart.) Griseb (AP) exhibits promising antioxidant
Possatorn Aon-im   +7 more
wiley   +1 more source

Coronary artery disease and depression [PDF]

open access: yes, 2017
Coronary artery disease (CAD) as well as depression are both highly prevalent diseases. Both cause a significant decrease in quality of life for the patient and impose a significant economic burden on society.
Langewitz, Wolf   +3 more
core  

Neurochemical Modulating Effect of Boswellia serrata Roxb. ex Colebr: A Preclinical Research

open access: yesPharmaceutical and Biomedical Research, 2022
Background: Boswellia serrata has been known for many decades and mentioned in the ancient Ayurvedic texts. Many previous studies have demonstrated its role in depression and anxiety in animal models.
Prabhakar Adake   +2 more
doaj  

Biodegradable Films Incorporated With Peels of Jatobá (Hymenaea courbaril L.) and Pomegranate Fruit (Punica granatum L.) Extracts for Preserving Chicken Breast Fillets

open access: yesJournal of Food Safety, Volume 45, Issue 6, December 2025.
First the pomegranate and jatobá peel extracts were obtained and phenolic compounds were determined by HPLC. Then, chitosan‐based films incorporated with extracts were prepared and applied to chicken breast fillet preservation. The fillets were stored at 4°C for 21 days and analyzed every 3 days for physicochemical and microbiological properties ...
Larissa Almeida Soares   +1 more
wiley   +1 more source

Antidepressants versus placebo for depression in primary care [PDF]

open access: yes, 2009
Background Concern has been expressed about the relevance of secondary care studies to primary care patients specifically about the effectiveness of antidepressant medication.
Arroll, Bruce   +7 more
core   +3 more sources

Synergistic Modulation of Microglial Polarization by Acteoside and Ferulic Acid via Dual Targeting of Nrf2 and RORγt to Alleviate Depression‐Associated Neuroinflammation

open access: yesAdvanced Science, Volume 12, Issue 43, November 20, 2025.
Machine‐learning‐directed phytochemical pair ACT/FA, administered at BDD's orthodox ratio, synergistically modulates microglial polarization via dual Nrf2/RORγt targeting to attenuate neuroinflammation and depressive behaviors. This concentration‐dependent synergism replicates the parent formula's efficacy while providing a mechanistic basis for ...
Dongjing Guo   +7 more
wiley   +1 more source

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