Results 61 to 70 of about 1,510,936 (205)

Risk of gastrointestinal bleeding by specific SSRIs and SNRIs: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, Volume 92, Issue 3, Page 793-808, March 2026.
Aim The purpose of this study is to estimate the risk of gastrointestinal bleeding (GIB) by selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine reuptake inhibitors (SNRIs) individual agents. Methods A systematic review was conducted for each unique antidepressant (i.e.
Ainhoa Gomez‐Lumbreras, Abdelrahman G. Tawfik, Guilherme Del Fiol, Kensaku Kawamoto, Thomas Reese, Katy Trinkley, Aubrey Jones, James Mitchell, Daniel C. Malone   +8 more
wiley   +1 more source

The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes

Clinical Pharmacology &Therapeutics, Volume 119, Issue 3, Page 696-702, March 2026.
Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali, Stephan van Erp, Cornelis Kramers, Cornelis J. Tack, Bastiaan E. de Galan   +4 more
wiley   +1 more source

Warfarin: pharmacological profile and drug interactions with antidepressants

Einstein (São Paulo), 2012
Oral anticoagulants are among the drugs with the greatest number of drug interactions. The concomitant use of several medications is a common practice in patients with cardiovascular problems, who often also present with depression; therefore, the ...
Juliana Souto Teles, Ellen Yukie Fukuda, David Feder   +2 more
doaj  

Assessment of the 3-substituted thietane-1,1-dioxide derivative antidepressant effect using rat model of depression induced by reserpine

Research Results in Pharmacology
Introduction: 3-ethoxythietane-1,1-dioxide (3ETD) is a novel molecule that has demonstrated significant antidepressant properties when administered intraperitoneally (i.p.) to mice once or repeatedly.
Irina L. Nikitina, Gulnara G. Gaisina, Elena E. Klen, Lyubov A. Tkachenko   +3 more
doaj   +1 more source

Antidepressants in Spine Surgery: A Systematic Review to Determine Benefits and Risks [PDF]

Asian Spine Journal, 2019
Antidepressant drugs can be advantageous in treating psychiatric and non-psychiatric illnesses, including spinal disorders. However, spine surgeons remain unfamiliar with the advantages and disadvantages of the use of antidepressant drugs as a part of ...
Ahmed B. Bayoumi, Oyku Ikizgul, Ceren Nur Karaali, Selma Bozkurt, Deniz Konya, Zafer Orkun Toktas   +5 more
doaj   +1 more source

Biochemical and Physiological Effects of Galanin in Health and Disease

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles, Yubo Wang, Kathryn Rhodes, Sharon DeMorrow   +3 more
wiley   +1 more source

Cognitive training, alone and combined with acetylcholinesterase inhibitors, in neurocognitive disorders: long‐term efficacy and the role of cognitive reserve on 30 months of intervention

Alzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.
Abstract INTRODUCTION Non‐pharmacological interventions are increasingly relevant in neurocognitive disorders (NCDs) management. Cognitive training (CT) may benefit early stages, when functional resources allow targeted stimulation. However, its long‐term effects and interaction with acetylcholinesterase inhibitors (AChEI) remain underexplored.
Adele Ravelli, Chiara Ceolin, Marina De Rui, Alessandra Coin, Giuseppe Sergi, Daniela Mapelli, Maria Devita   +6 more
wiley   +1 more source

Alternanthera philoxeroides (Mart.) Griseb Mitigates Age‐Related Depression in Mice Through Regulation of Oxidative Stress and Neurogenic Mechanisms

Advances in Pharmacological and Pharmaceutical Sciences, Volume 2026, Issue 1, 2026.
Depression adversely impacts daily life, with age‐related neurodegeneration being a significant contributing factor. Neurodegenerative alterations, often accelerated by oxidative stress, underlie depressive progression in advanced age. Our previous research has reported that Alternanthera philoxeroides (Mart.) Griseb (AP) exhibits promising antioxidant
Possatorn Aon-im, Orawan Monthakantirat, Yaowared Chulikhit, Supawadee Daodee, Chantana Boonyarat, Anake Kijjoa, Charinya Khamphukdee, Anjali Chauhan   +7 more
wiley   +1 more source

Antidepressant use and the components of the frailty syndrome

Revista Brasileira de Geriatria e Gerontologia, 2018
Objective: to evaluate the effects of antidepressant use on components of frailty. Methods: a cross-sectional and analytical study comparing groups of users and non-users of antidepressants was carried out in a municipal region in the south of Brazil ...
Vanessa Adelina Casali Bandeira, Evelise Moraes Berlezi, Carolina Baldissera Gross, Christiane de Fátima Colet   +3 more
doaj   +2 more sources

A Systematic Review of Community Pharmacy‐Led Depression Services: Service Components, Outcomes, and Implementation Barriers and Facilitators

Depression and Anxiety, Volume 2026, Issue 1, 2026.
Background Depression is the most common mental ill health condition, and its prevalence is increasing. Despite this, its treatment is variable often due to a lack of capacity within healthcare systems to support this vulnerable population. Community pharmacy staff could offer additional support.
David Kernaghan, Hisham Alshammari, Gazala Akram, Judith Pratt, Margaret Maxwell, Margaret C. Watson, Natalie Weir, Samraggi Choudhury   +7 more
wiley   +1 more source