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“Caring for Junior” - A Problem-Based Learning Case
Introduction Epidemiological studies suggest that as many as 45% of adults 85 years or older have cognitive impairment. To help prepare our first-year medical students to work with this population, we created this problem-based learning case. Methods The
Jonathan Flacker, Theodore Johnson
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Antidepressant Use and the Risk of Mood Instability
N/a.
Tomás Teodoro
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Effectiveness of a recent topical sialogogue in the management of drug-induced xerostomia [PDF]
Objectives: Use of certain drugs is the most common aetiology of xerostomia. Systemic sialogogues provide a longer effect than topic ones, but also induce relevant side effects. Topical sialogogues, as malic acid, allow a safe use as they
Aguilar Salvatierra, Antonio+3 more
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Background Antipsychotics are commonly prescribed in high doses in combination with multiple psychotropic drugs. This study focused on the high‐dose antipsychotic prescriptions in patients with schizophrenia, while aiming to identify their associations ...
Tatsuichiro Takahashi+4 more
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Network reconstruction of platelet metabolism identifies metabolic signature for aspirin resistance. [PDF]
Recently there has not been a systematic, objective assessment of the metabolic capabilities of the human platelet. A manually curated, functionally tested, and validated biochemical reaction network of platelet metabolism, iAT-PLT-636, was reconstructed
Bordbar, Aarash+4 more
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Zebrafish as an Animal Model for Testing Agents with Antidepressant Potential [PDF]
Depression is a serious mental disease that, according to statistics, affects 320 million people worldwide. Additionally, a current situation related to the COVID-19 pandemic has led to a significant deterioration of mental health in people around the world.
Joanna Lachowicz+6 more
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The Use Of Mirtazapine As A Hypnotic [PDF]
Prescription of approved hypnotics for insomnia decreased by more than 50%, whereas of antidepressive agents outstripped that of hypnotics. However, there is little data on their efficacy to treat insomnia, and many of these medications may be associated
Francisca Magalhães Scoralick+2 more
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Switch to hypomania induced by repetitive transcranial magnetic stimulation and partial sleep deprivation added to antidepressant: A case report [PDF]
Introduction. Bipolar depression is often unrecognized and difficult to treat because of two opposite problems: treatment resistance and risk of manic switch. Case report.
Ilić Tihomir V., Krstić Jelena
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Background Prior studies reported that exposure to antidepressants during pregnancy may be associated with gestational hypertension. The aim of this study is to assess the association between the use of antidepressants during pregnancy and the risk of ...
Neily Zakiyah+5 more
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Background Low-grade glioma (LGG) is a relatively rare type of brain tumour. The use of antidepressant, sedative and anti-epileptic drugs can reflect the burden of the disease.
Isabelle Rydén+7 more
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