Results 31 to 40 of about 3,249,142 (188)

PET studies of the serotonin system in major depression and its treatment [PDF]

, 2014
The serotonin system has been implicated in major depression since the 1960s, mainly based on the serotonin enhancing properties of antidepressants.
Tiger, Mikael
core   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Do antidepressants cure or create abnormal brain states? [PDF]

, 2006
Moncrieff and Cohen argue that psychotropic drugs create abnormal states that may co-incidentally relieve symptoms of mental ...
Beasley, Beasley, Bourin, Breggin, Cohen, David Cohen, Delgado, Deptula, Dewa, Drevets, Dumont, Emrich, Fisher, Furlan, Goldberg, Harmer, Harmer, Herrmann, Hyman, Imlah, Joanna Moncrieff, Kennedy, Kirsch, Knegtering, Lacasse, Leo, Lowther, Malhi, Matsubara, Mayers, Meyer, Moncrieff, Moncrieff, Moncrieff, Moncrieff, Murphy, Niklson, Parsey, Patten, Pilgrim, Ramaekers, Ramaekers, Raptopoulos, Reivich, Rickels, Robbe, Robertson, Robinson, Rush, Sargent, Schildkraut, Stockmeier, Tranter, Tuma, Van Putten, Wingen   +55 more
core   +3 more sources

Biodegradable Films Incorporated With Peels of Jatobá (Hymenaea courbaril L.) and Pomegranate Fruit (Punica granatum L.) Extracts for Preserving Chicken Breast Fillets

Journal of Food Safety, Volume 45, Issue 6, December 2025.
First the pomegranate and jatobá peel extracts were obtained and phenolic compounds were determined by HPLC. Then, chitosan‐based films incorporated with extracts were prepared and applied to chicken breast fillet preservation. The fillets were stored at 4°C for 21 days and analyzed every 3 days for physicochemical and microbiological properties ...
Larissa Almeida Soares, Luciana Cristina Lins de Aquino Santana   +1 more
wiley   +1 more source

THE PSYCHOMOTOR THEORY OF HUMAN MIND [PDF]

, 2007
This study presents a new theory to explain the neural origins of human mind. This is the psychomotor theory. The author briefly analyzed the historical development of the mind-brain theories.
TAN, Prof. Dr. Uner
core   +1 more source

Synergistic Modulation of Microglial Polarization by Acteoside and Ferulic Acid via Dual Targeting of Nrf2 and RORγt to Alleviate Depression‐Associated Neuroinflammation

Advanced Science, Volume 12, Issue 43, November 20, 2025.
Machine‐learning‐directed phytochemical pair ACT/FA, administered at BDD's orthodox ratio, synergistically modulates microglial polarization via dual Nrf2/RORγt targeting to attenuate neuroinflammation and depressive behaviors. This concentration‐dependent synergism replicates the parent formula's efficacy while providing a mechanistic basis for ...
Dongjing Guo, Qiancheng Mao, Xinyu Fang, Liuxuan Huang, Haoquan Tian, Wenguang Yang, Feiyue Zhou, Ke Ma   +7 more
wiley   +1 more source

Near‐Death Experience During Emergency Ketamine Use: A Case Report

Brain and Behavior, Volume 15, Issue 10, October 2025.
We report a near‐death experience in a 73‐year‐old woman with acute respiratory failure who received an accidental 500 mg ketamine dose during intubation. Semi‐structured interviews revealed a vivid and evolving NDE narrative, followed by lasting psychological transformation, underscoring the clinical and research significance of NDEs in critical care.
Pauline Fritz, Anaïs Pichelin, Aurore Ancion, Naji Alnagger, Nicolas Lejeune, Alexandre Ghuysen, Olivia Gosseries, Charlotte Martial   +7 more
wiley   +1 more source

Coronary artery disease and depression [PDF]

, 2017
Coronary artery disease (CAD) as well as depression are both highly prevalent diseases. Both cause a significant decrease in quality of life for the patient and impose a significant economic burden on society.
Langewitz, Wolf, Osterwalder, Remo H., Pfisterer, Matthias E., Zellweger, Michael J.   +3 more
core  

Sarcopenic Obesity Phenotype Index (SOPi): A Population‐Based Study

Journal of Cachexia, Sarcopenia and Muscle, Volume 16, Issue 5, October 2025.
ABSTRACT Background Sarcopenic obesity (SO) is a clinical condition defined by the coexistence of high body fat mass and low muscle function and mass, which increases the risk of adverse health outcomes, including disability and mortality. Early detection and frequent monitoring of SO are essential for preventive interventions and management strategies.
Elizabeth Benz, Alexandre Pinel, Christelle Guillet, Frederic Capel, Bruno Pereira, Dimitris Rizopoulos, Alfonso J. Cruz‐Jentoft, Doris Eglseer, Eva Topinkova, Rocco Barazzoni, Lorenzo M. Donini, Fernando Rivadeneira, Marinka Steur, Trudy Voortman, Peter J. M. Weijs, Josje D. Schoufour, Yves Boirie   +16 more
wiley   +1 more source