Los placebos, el dolor neuropàtico y de género
Acta Neurológica Colombiana, 2023 INTRODUCTION: the placebos' analgesic effect seems to depend on different factors such as socio-cultural, psychological and genetic aspects. The effects of gender on placebos' analgesic response have rarely been documented in clinical studies, even ...
Carlos B. Moreno +1 more
doaj +2 more sources
Antidepressive and anxiolytic effects of ostruthin, a TREK-1 channel activator [PDF]
, 2018 We screened a library of botanical compounds purified from plants of Vietnam for modulators of the activity of a two-pore domain K+ channel, TREK-1, and we identified a hydroxycoumarin-related compound, ostruthin, as an activator of this channel ...
Joseph, Ancy +3 more
core +2 more sources
Severe hyponatremia and the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with fluoxetine: case report [PDF]
Arquivos de Neuro-Psiquiatria, 2006 Hyponatremia is a significant complication of treatment with serotonin selective reuptake inhibitors (SSRI). We describe a case of a 53-year-old woman that was started on fluoxetine 20 mg/day for depression.
Carlos Alexandre Twardowschy +3 more
doaj +1 more source
Antidepressant drugs and the response in the placebo group: the real problem lies in our understanding of the issue [PDF]
, 2012 In a recent paper, Horder and colleagues (Horder et al., 2010, J Psychopharmacol 25: 1277–1288) have suggested that the mainproblem in the Kirsch analysis is methodological. We argue that the results are similar irrespective of the method used.
Bech P +8 more
core +1 more source
Phenolic Acids as Antidepressant Agents
Nutrients, 2022 Depression is a psychiatric disorder affecting the lives of patients and their families worldwide. It is an important pathophysiology; however, the molecular pathways involved are not well understood. Pharmacological treatment may promote side effects or be ineffective.
Maria Lúcia da Silva Cordeiro +5 more
openaire +2 more sources
Post-stroke depression modulation and in vivo antioxidant activity of gallic acid and its synthetic derivatives in a murine model system [PDF]
, 2016 Gallic acid (3,4,5-trihydroxybenzoic acid, GA) is a plant secondary metabolite, which shows antioxidant activity and is commonly found in many plant-based foods and beverages.
Antoni Sureda +9 more
core +2 more sources
Frontiers in Psychiatry, 2016 Executive function deficits such as working memory, decision-making, and attention problems are a common feature of several psychiatric disorders for which no satisfactory treatment exists.
Therese eVan Amelsvoort, Dennis eHernaus
doaj +1 more source
Network reconstruction of platelet metabolism identifies metabolic signature for aspirin resistance. [PDF]
, 2014 Recently there has not been a systematic, objective assessment of the metabolic capabilities of the human platelet. A manually curated, functionally tested, and validated biochemical reaction network of platelet metabolism, iAT-PLT-636, was reconstructed
Bordbar, Aarash +4 more
core +2 more sources
Effectiveness of a recent topical sialogogue in the management of drug-induced xerostomia [PDF]
, 2011 Objectives: Use of certain drugs is the most common aetiology of xerostomia. Systemic sialogogues provide a longer effect than topic ones, but also induce relevant side effects. Topical sialogogues, as malic acid, allow a safe use as they
Aguilar Salvatierra, Antonio +3 more
core +1 more source
The Use Of Mirtazapine As A Hypnotic [PDF]
Geriatrics, Gerontology and AgingPrescription of approved hypnotics for insomnia decreased by more than 50%, whereas of antidepressive agents outstripped that of hypnotics. However, there is little data on their efficacy to treat insomnia, and many of these medications may be associated
Francisca Magalhães Scoralick +2 more
doaj +1 more source