In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski +7 more
wiley +1 more source
Pharmacological and Phytochemical Insights Into <i>Ficus benghalensis</i> (Indian Banyan): Anti-Inflammatory, Antioxidant, and Anticancer Potentials. [PDF]
Ali Z +9 more
europepmc +1 more source
ABSTRACT Background Diabetes mellitus (DM) induces multifaceted cellular and structural alterations in the male reproductive system, thereby predisposing to infertility. Objectives This study aimed to evaluate the morphological, stereological, biochemical, histopathological, and ultrastructural changes induced by DM in testicular tissue, and to ...
Ayşenur Kaya Mutlu, Süleyman Kaplan
wiley +1 more source
Repurposing Antidiabetic Medications for Parkinson's Disease: Focus on Biomarker Strategies for Disease Modification. [PDF]
Yelleswarapu NK, Sidiropoulos C.
europepmc +1 more source
ABSTRACT Introduction Gender‐affirming hormone therapy (GAHT) may be associated with increased cardiometabolic disease (CMD) risk. Prospective CMD risk screening is recommended, but long‐term data are needed regarding changes in CMD markers. Objectives To evaluate prospective changes in CMD risk markers during GAHT.
Louise Lehmann Christensen +7 more
wiley +1 more source
Inhibition of Diabetes-Related Enzymes by Plant Secondary Metabolites: A Promising Therapeutic Strategy. [PDF]
Șeremet OC +6 more
europepmc +1 more source
Outcomes of a Novel Surgery: Gastrojejunal-Ileal Interposition with Bipartition and Sleeve Gastrectomy for Type 2 Diabetes and Obesity. [PDF]
Demirel T, Sut N, Ugale S.
europepmc +1 more source
Peptidomic profiling and molecular dynamics study of bioactive peptides from fermented camel milk: considering the fermentation time dependent proteolysis by <i>Lactobacillus</i> and <i>Saccharomyces</i> with antidiabetic, antioxidative and anti-inflammatory activities. [PDF]
Padhiyar PN +9 more
europepmc +1 more source
Mogrosides as Dual-Function Sweeteners: A Comprehensive Review of Extraction, Metabolism, Antidiabetic Mechanisms, and Food Applications. [PDF]
Feng Q +5 more
europepmc +1 more source
Polyphenols of <i>Zingiber roseum</i> Leaf as a Potential Source of α‑Glucosidase Inhibitors for Type‑2 Diabetes Management: LC-MS/MS, Pharmacological and Computational Analysis. [PDF]
Sakib MS +9 more
europepmc +1 more source

