Results 111 to 120 of about 1,672 (158)

Dissociation between opiate-like and antidiarrheal activities of antidiarrheal drugs.

The Journal of Pharmacology and Experimental Therapeutics, 1979
Three synthetic antidiarrheals, diphenoxylate, loperamide and SC 27166, and two narcotics, morphine and codeine, were evaluated in rats by the intravenous and oral route for specificity and duration of their antidiarrheal, opiate-like and acute toxic effects.
C J, Niemegeers, J L, McGuire, J J, Heykants, P A, Janssen   +3 more
openaire   +2 more sources

Antidiarrheal Drug Therapy

Current Gastroenterology Reports, 2017
Acute diarrhea often runs a self-limited course and little by way of treatment is needed except for oral rehydration therapy. Chronic diarrhea poses a longer-term problem. If not treatable with specific therapy aimed at the underlying pathophysiology, chronic diarrhea often needs long-term symptomatic therapy.This paper aims to examine the options for ...
openaire   +2 more sources

Antimicrobial and Antidiarrheal drugs Survey

World Journal of Pharmaceutical Sciences, 2022
Diarrhea is a major health problem throughout the world and it has become more problematic in developing countries like Ethiopia. People, in several parts of the world, use different traditional medicines for treating diarrhea and it has been reported that the roots, leaves, and flowers of various species are used for the same purpose.
Suthar Mona, Makwana Rajeshree, Jain Priyanshi, Dholekar Ekta   +3 more
openaire   +1 more source

Spinally mediated opioid antidiarrheal effects

European Journal of Pharmacology, 1991
To assess the role of opioid receptors in the spinal cord in regulation of functions of the intestinal mucosa in a secretory model, we evaluated the ability of i.t. administered mu (PL017), delta (DPDPE) and kappa (U50,488H) selective opioid agonists to inhibit diarrhea produced in mice by an injection of prostaglandin E2 (PGE2) (200 micrograms/mouse ...
P K, Lemcke, J E, Shook, T F, Burks
openaire   +2 more sources

MECHANISMS OF ANTIDIARRHEAL EFFECT BY PROBIOTICS

Journal of Pediatric Gastroenterology and Nutrition, 2016
Gastroenteritis is a major cause of morbidity and mortality worldwide. Several microbial pathogens cause secretory diarrhea such as Vibrio cholerae and enterotoxigenic Escherichia coli as well as enteric viruses such as Rotavirus (RV) and Norovirus and parasites including Cryptosporidium.
A. Guarino, E. Ruberto, V. Buccigrossi
openaire   +1 more source

Pharmacology of Antidiarrheal Drugs

Annual Review of Pharmacology and Toxicology, 1983
F, Awouters, C J, Niemegeers, P A, Janssen   +2 more
openaire   +2 more sources

Evaluation of an Antidiarrheal Agent

JAMA, 1964
H P, AIDEM, L D, BAKER
openaire   +2 more sources

Antidiarrheal Agents

2021
openaire   +1 more source

Development of New Antidiarrheal Medications

Journal of Clinical Gastroenterology, 1983
L E, Rosenthal, J, Pressman, K, Dharmsathaphorn   +2 more
openaire   +2 more sources

Global, regional, and national consumption of controlled opioids: a cross-sectional study of 214 countries and non-metropolitan territories

British Journal of Pain, 2022
Carl Heneghan, Kamal Mahtani, Georgia C Richards   +2 more
exaly