Results 161 to 170 of about 6,301 (229)

Spinally mediated opioid antidiarrheal effects

European Journal of Pharmacology, 1991
To assess the role of opioid receptors in the spinal cord in regulation of functions of the intestinal mucosa in a secretory model, we evaluated the ability of i.t. administered mu (PL017), delta (DPDPE) and kappa (U50,488H) selective opioid agonists to inhibit diarrhea produced in mice by an injection of prostaglandin E2 (PGE2) (200 micrograms/mouse ...
P K, Lemcke, J E, Shook, T F, Burks
openaire   +2 more sources

MECHANISMS OF ANTIDIARRHEAL EFFECT BY PROBIOTICS

Journal of Pediatric Gastroenterology and Nutrition, 2016
Gastroenteritis is a major cause of morbidity and mortality worldwide. Several microbial pathogens cause secretory diarrhea such as Vibrio cholerae and enterotoxigenic Escherichia coli as well as enteric viruses such as Rotavirus (RV) and Norovirus and parasites including Cryptosporidium.
A. Guarino, E. Ruberto, V. Buccigrossi
openaire   +1 more source

Polyamine analogue antidiarrheals: a structure-activity study.

Journal of Medicinal Chemistry, 2001
Raymond J. Bergeron, J. Wiegand, J. Mcmanis, W. Weimar, Richard E. Smith, Samuel E. Algee, Tammy L. Fannin, M. Slusher, P. Snyder   +8 more
semanticscholar   +1 more source

CFTR chloride channel drug discovery--inhibitors as antidiarrheals and activators for therapy of cystic fibrosis.

Current pharmaceutical design, 2006
A. Verkman, G. Lukács, Luis J. V. Galietta   +2 more
semanticscholar   +1 more source

Dependence liability of two antidiarrheals, nufenoxole and loperamide

Clinical pharmacology and therapy, 1980
A. Korey, D. H. Zilm, Edward M. Sellers
semanticscholar   +1 more source

Normalization of small intestinal propulsion with loperamide-like antidiarrheals in rats.

European Journal of Pharmacology, 1990
A. Megens, L. L. J. Canters, Frans H. L. Awouters, C. Niemegeers   +3 more
semanticscholar   +1 more source

Potential antisecretory antidiarrheals. 2. Alpha 2-adrenergic 2-[(aryloxy)alkyl]imidazolines.

Journal of Medicinal Chemistry, 1990
A. Moormann, B. Pitzele, P. Jones, G. Gullikson, D. Albin, S.-S. Yu, R. Bianchi, E. L. Sanguinetti, B. Rubin, M. Grebner   +9 more
semanticscholar   +1 more source

Potential antisecretory antidiarrheals. 1. Alpha 2-adrenergic aromatic aminoguanidine hydrazones.

Journal of Medicinal Chemistry, 1988
B. Pitzele, A. Moormann, Gary W. Gullikson, D. Albin, R. Bianchi, Prima Palicharla, Elizabeth L. Sanguinetti, D. Walters   +7 more
semanticscholar   +1 more source

Pharmacology of Antidiarrheal Drugs

Annual Review of Pharmacology and Toxicology, 1983
F, Awouters, C J, Niemegeers, P A, Janssen   +2 more
openaire   +2 more sources

The castor oil test in rats: An in vivo method to evaluate antipropulsive and antisecretory activity of antidiarrheals?

, 1984
C. Niemegeers, F. Awouters, P. A. Janssen   +2 more
semanticscholar   +1 more source