Results 41 to 50 of about 1,664 (156)

Gastroprotective Effects of Hexanic Extract of the Leaves of Spondias purpurea and Its Underlying Mechanism of Action

open access: yesJournal of Food Process Engineering, Volume 49, Issue 6, June 2026.
Histopathological analysis of gastric mucosa stained with HE and PAS of rats submitted to induction of ulcers with acetic acid. The animals were treated orally with vehicle (injured control), ranitidine, and SpHE (25 mg/kg) for 14 days. In A and B, observe preserved mucosa and submucosal layers (black asterisk) and presence of the barrier protection of
Cynthia Layse Ferreira de Almeida   +9 more
wiley   +1 more source

Prevalence and Impact of Disorders of Gut–Brain Interaction in France: Results From the Rome Foundation Global Epidemiology Study

open access: yesNeurogastroenterology &Motility, Volume 38, Issue 6, June 2026.
Nearly half of adults in France meet Rome IV criteria for disorders of gut–brain interaction, with substantial impairment in quality of life and increased healthcare utilization. Despite this burden, most individuals report no prior medical diagnosis, highlighting persistent challenges in recognition and care.
Tiffany Vo   +7 more
wiley   +1 more source

Antidiarrheal activity of α-terpineol in mice

open access: yesBiomedicine & Pharmacotherapy, 2019
Diarrhea is one of the leading causes of infant death in the world accounting for high child mortality rate. It is also present in different pathophysiologies related to several etiological agents. The aim of this study is to investigate the antidiarrheal effect of α -Terpineol (α-TPN) in different diarrhea models in rodents.
Polyanna dos Santos Negreiros   +9 more
openaire   +2 more sources

Pharmacological Evaluation of Methanolic Fruit Extract of Lannea coromandelica: Antioxidant, Cytotoxic, Antidiabetic, Antibacterial, Anti‐Inflammatory, and Sedative Activities

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Phytochemical investigation of Lannea coromandelica through GC–MS and in silico analysis revealed diverse bioactive compounds with promising pharmacological potential. Integrated in vitro and in vivo assays demonstrated significant antioxidant, antidiabetic, antibacterial, anti‐inflammatory, and sedative activities, supporting its therapeutic relevance.
Priota Islam Meem   +7 more
wiley   +1 more source

Chemical Profiling, Pharmacological Activities, and Toxicity Assessment of Juniperus phoenicea sp. turbinata L. Extract: Integrated In Vitro, In Vivo, and In Silico Insights

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Hydroethanolic leaf and fruit extracts of Juniperus phoenicea showed high phenolic content, dominated by ferulic acid. Both extracts were non‐toxic and exhibited strong anti‐inflammatory, analgesic, antioxidant, and antimicrobial activities. Molecular docking confirmed stable binding to key inflammatory and microbial targets, supporting its ...
Tarik Chelouati   +13 more
wiley   +1 more source

Malnutrition and diabetes outcomes 12 months after total pancreatectomy: A descriptive cohort study

open access: yesJournal of Parenteral and Enteral Nutrition, Volume 50, Issue 4, Page 573-581, May 2026.
Abstract Background Total pancreatectomy is a rare but increasingly performed surgical procedure that systematically induces endocrine and exocrine pancreatic insufficiency. Data on long‐term nutritional outcomes after this surgery are limited. The objective of this study was to assess the prevalence of malnutrition at 3 months and 12 months after ...
Ibrahima Maiga   +5 more
wiley   +1 more source

Loperamide: From antidiarrheal to analgesic

open access: yesJournal of Opioid Management, 2013
Loperamide, an antidiarrheal drug has been observed to produce analgesia in animal models of pain. However, the exact mechanism underlying loperamide analgesia needs further studies.
openaire   +3 more sources

Enterocolitis and other immunotherapy and targeted therapy-related gastrointestinal manifestations: A review for gastroenterologist

open access: yesRevista de Gastroenterología de México (English Edition)
New oncologic treatments, particularly immunotherapy (IT), have revolutionized the treatment of advanced-stage malignant tumors. Immune checkpoint inhibitors are the main form of IT and act by increasing T cell activity and the organism’s immune response
O. Gómez Escudero
doaj   +1 more source

Relación entre autocuidado y automedicación en estudiantes de ciencias de salud de una universidad pública

open access: yesNURE Investigación
Objetivo. Analizar la prevalencia de la automedicación y su relación con la capacidad de autocuidado en estudiantes del Centro de Ciencias de la Salud de una universidad pública. Metodología.
Arely Paulina Diaz Nieves   +3 more
doaj   +1 more source

Pharmacologic treatment of irritable bowel syndrome. Position statement of the Asociación Mexicana de Gastroenterología, 2024

open access: yesRevista de Gastroenterología de México (English Edition)
Introduction: The aim of this position statement is to provide health professionals with an updated and evidence-based guideline for the pharmacologic management of irritable bowel syndrome (IBS) in Mexico.
J.M. Remes-Troche   +13 more
doaj   +1 more source

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