Results 61 to 70 of about 6,301 (229)

A Systematic Review of Antidiabetic Mechanisms of Passiflora edulis: Beyond Glycemic Control

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Passiflora edulis demonstrates multitarget antidiabetic effects in preclinical models, particularly through peel‐derived preparations rich in pectin and flavonoids. The evidence indicates improvements in glycemic control, lipid metabolism, oxidative stress, and inflammation, involving pathways related to glucose absorption, insulin signaling, AMPK ...
Luiz Ricardo Teixeira de Farias, Mariáurea Matias Sarandy, Reggiani Vilela Gonçalves, Emanuella de Aragão Tavares, Silvana Maria Zucolotto   +4 more
wiley   +1 more source

Phytochemical Fingerprinting of Sanchezia nobilis Hook. F. Leaf Extract and Evaluation of Anxiolytic, Cytotoxic, and Antioxidant Activities In Vivo, In Vitro, and In Silico

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
GC‐MS fingerprinting demonstrated that ethanolic leaf extract of Sanchezia nobilis (SNE) many phytochemicals out of which aniline and isoquinoline showed potential binding affinity to alpha1GABAA receptor responsible for anxiolytic effects. In vitro studies confirmed antioxidant effects of SNE.
Progga Paramita Paul, Musfiqur Rahman Sakib, Pritam Kundu, Dabashis Chakraborty, Tasnim Fatema, Shahriar Hossen, Ahsan Abid, Trina Mitra, Manik Chandra Shill, Utpal Kumar Karmakar   +9 more
wiley   +1 more source

Efficacy of Fermented Brown Rice by Aspergillus oryzae (FBRA) in Ulcerative Colitis: A Double‐Blind Randomized Trial

JGH Open, Volume 10, Issue 10, October 2026.
ABSTRACT Background Ulcerative colitis (UC) is a diffuse, nonspecific inflammation of the colon of unknown cause. Basic and clinical studies suggest that UC may be ameliorated by dietary fiber intake. Fermented brown rice by Aspergillus oryzae (FBRA) is produced by fermenting brown rice and bran with A. oryzae. We aimed to evaluate the efficacy of FBRA
Hideki Ishikawa, Yoshinari Onishi, Keiko Kataoka, Yoshitaka Murakami, Michihiro Mutoh, Hiroshi Kobayashi   +5 more
wiley   +1 more source

All‐Oral PI3Kδ and HDAC Inhibition with Parsaclisib Plus Chidamide and Step‐Down Maintenance in Relapsed or Refractory Peripheral T‐Cell Lymphoma: A Phase Ib Trial

MedComm, Volume 7, Issue 10, October 2026.
ABSTRACT Single‐agent targeted therapies for relapsed or refractory peripheral T‐cell lymphoma (R/R peripheral T‐cell lymphoma [PTCL]) produce modest, short‐lived responses, underscoring the need for tolerable, chemotherapy‐free combinations. In an open‐label, single‐arm Phase Ib trial at two tertiary hospitals, we evaluated parsaclisib plus chidamide ...
Xufeng Luo, Zheng Yan, Wei Fang, Hanchi Duan, Qiuyu Zhang, Haiying Wang, Shuna Yao, Jiuyang Zhang, Yiping Jin, Wenyong Li, Xiaolu Teng, Lina Zhang, Lijie Liang, Quande Lin, Ping Wang, Haoran Si, Jinxin Miao, Wenping Zhou, Zhihua Yao, You‐Wen He, Qingxin Xia, Yanyan Liu   +21 more
wiley   +1 more source

Prophylactic use of antidiarrheal agents to control diarrhea associated with lapatinib therapy in breast cancer patients.

, 2015
205 Background: Lapatinib causes diarrhea in about 40-50% of patients treated with it for HER-2 positive breast cancer. It is the major dose and treatment limiting toxicity of lapatinib.
Muhammad Omer Jamil, John T. Carpenter, Maira Rizwan   +2 more
core   +1 more source

Gastrointestinal adverse effects of GLP‐1 receptor agonists and dual GIP/GLP‐1 receptor agonists: A narrative expert review of approved therapies, oral formulations, and pipeline agents

Nutrition in Clinical Practice, Volume 41, Issue 5, Page 1318-1333, October 2026.
Abstract Background Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and dual glucose‐dependent insulinotropic polypeptide (GIP)/GLP‐1 receptor agonists have transformed the management of type 2 diabetes and obesity. Gastrointestinal (GI) adverse events are the most common limitation of these therapies and a leading cause of discontinuation ...
Vikash Singhani, Muhammad Ehsan, Sara Valencia, Ahmed Nadeem, Eisha Moazzam, Winfield Scott Butsch, Samita Garg   +6 more
wiley   +1 more source

Distinct Symptom Occurrence Subgroups Among Patients With Colorectal Cancer: Differences in Social Determinants of Health and Diet Quality

Research in Nursing &Health, Volume 49, Issue 5, Page 595-611, October 2026.
ABSTRACT Colorectal cancer (CRC) is a leading cause of cancer mortality in the United States. Many patients with CRC experience physical and psychological symptoms that diminish quality of life and are shaped by social determinants of health (SDOH) and diet quality.
Youran Lee, Qing Yang, Melissa Kay, Donald E. Bailey, Biljana Gigic, Sheetal Hardikar, Adetunji T. Toriola, David Shibata, Christopher I. Li, Doratha A. Byrd, Jane C. Figueiredo, Ildiko Strehli, Megan Mclaws, Vaia Florou, Mmadili Ilozumba, Patricia Erickson, Apurva Medhe, Cornelia M. Ulrich, Rosa M. Gonzalez‐Guarda   +18 more
wiley   +1 more source

Ceratonia siliqua: Phytochemistry, Bioactivity, and Its Emerging Role as a Sustainable Food and Industrial Resource

Journal of Food Science, Volume 91, Issue 10, October 2026.
ABSTRACT Ceratonia siliqua L. (C. siliqua), commonly known as the carob tree, is an evergreen species of the Fabaceae family native to the Mediterranean basin and increasingly cultivated worldwide. Traditionally valued as animal feed and a natural sweetener, it has recently gained recognition as a multifunctional plant resource with nutritional ...
Anis Ben Hsouna, Ravendra Kumar, Manjul Gondwal, Shivangi Chamoli, Bhanu Pratap Singh Gautam, Simranpreet Kaur, Rakesh Kumar Verma, Piyush Kumar, Monika Michalak, Boutheina Ben Akacha, Wirginia Kukula‐Koch, Wojciech Koch, Faical Brini, Wissem Mnif, Rania Ben Saad, Stefania Garzoli, Miroslava Kačániová   +16 more
wiley   +1 more source

Bile Acid Metabolism as a Unifying Readout for Diet, Microbiome Function, and Gastrointestinal Disease

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Dietary components shape the gut microbiome, which modifies bile acids through transformations. The resulting bile acid pool is sensed by host receptors to regulate immunity, metabolism, and intestinal function. Targeted bile acid measurements provide a unifying readout to study diet‐microbiome interactions and to develop next‐generation dietary ...
Jason Dichter
wiley   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, Volume 38, Issue 51, 11 September 2026.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source