Results 111 to 120 of about 35,321 (251)

Nanozymes for Liver Disease Therapy: Advances in Catalytic Activity, Targeting Strategies, and Clinical Translation

open access: yesAdvanced Science, Volume 13, Issue 20, 9 April 2026.
Nanozymes, as enzyme‐mimicking nanomaterials, exhibit unique catalytic properties for the treatment of liver diseases. By regulating redox homeostasis, modulating immune responses, and enabling targeted delivery, nanozymes overcome the limitations of natural enzymes.
Xiandi Meng   +6 more
wiley   +1 more source

Fully Synthetic Non‐Carbohydrate Heparin Mimetics—Perspectives for Therapeutic Anticoagulation and Beyond?

open access: yesArchiv der Pharmazie, Volume 359, Issue 4, April 2026.
Fully synthetic sulfated non‐carbohydrate polymers for structurally mimicking the polysaccharide glycosaminoglycan heparin in its anticoagulant activities with further prospects to pleiotropic effects in oncology and in antiviral approaches. ABSTRACT Heparin is one of the oldest drugs on the market.
Katrin Nekipelov   +2 more
wiley   +1 more source

When Rare Is Not Small: Amyotrophic Lateral Sclerosis Initiatives and Therapy

open access: yesExploration, Volume 6, Issue 2, April 2026.
In the precision‐medicine era, rare diseases must not be sidelined in translational infrastructure. The Mr. Cai Lei—led “Ice‐Breaking Team” turns an amyotrophic lateral sclerosis patient community into a sustainable ecosystem, realigning philanthropy, data, and research and development to reshape rare‐disease pipelines and guide precision therapies ...
Yang Liu   +6 more
wiley   +1 more source

The characteristics and prognostic factors on initial presentation to healthcare facilities associated with poor outcomes in acute or acute‐on‐chronic digoxin poisoning in Hong Kong

open access: yesHong Kong Journal of Emergency Medicine, Volume 33, Issue 2, April 2026.
Abstract Background Digoxin is a commonly used cardiovascular drug but has a narrow therapeutic window, and its poisoning could be fatal. Prognostic factors of digoxin poisoning were proposed largely based on the toxicokinetics of digoxin. Higher levels of evidence on this topic were limited.
Pui Hang Belle Lau   +7 more
wiley   +1 more source

Female Sex as a Major Risk Factor for Dabigatran‐Induced Esophagitis in Atrial Fibrillation Ablation

open access: yesJournal of Arrhythmia, Volume 42, Issue 2, April 2026.
Dabigatran‐induced esophagitis occurred in 18.7% of patients undergoing atrial fibrillation ablation. Female sex was identified as an independent predictor of this complication, highlighting the need for careful periprocedural management and preventive strategies in women.
Daiki Saito   +16 more
wiley   +1 more source

Design of a randomized superiority trial of a brief couple treatment for PTSD. [PDF]

open access: yes, 2019
Interpersonal difficulties are common among veterans with posttraumatic stress disorder (PTSD) and are associated with poorer treatment response. Treatment outcomes for PTSD, including relationship functioning, improve when partners are included and ...
Becker, Julia   +12 more
core   +1 more source

Melodies of the forest: Nature as an improvisational space for shared creative embodiment

open access: yesPeople and Nature, Volume 8, Issue 4, Page 871-885, April 2026.
Abstract In an era marked by increasing disconnection from nature, innovative approaches to reconnect with the environment are crucial for both ecological and psychological well‐being. This paper explores how natural environments (a deciduous forest of Quebec in the present case study) can serve as an improvisational space for shared creative ...
Antoine Bellemare‐Pepin   +2 more
wiley   +1 more source

Delayed fomepizole initiation after massive ethylene glycol ingestion: a case report of survival with dialysis support

open access: yesУкраїнський Журнал Нефрології та Діалізу
Ethylene glycol poisoning is a rare but life-threatening intoxication. Early diagnosis is often difficult, as the initial presentation resembles ethanol intoxication, while later stages are characterized by severe high–anion gap metabolic acidosis ...
Konstantinos S. Mavromatidis   +1 more
doaj   +1 more source

Toxic alcohols [PDF]

open access: yes, 2018
Kraut, Jeffrey A, Mullins, Michael E
core   +2 more sources

Excessive Apixaban Concentrations in a Bleeding Patient Treated With Pharmacological Reversal and Extracorporal Removal—A Case Report

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
Excessive apixaban concentrations in a bleeding patient leading to impaired coagulation and treatment with pharmacological reversal and extracorporal removal. ABSTRACT In trauma, even therapeutic apixaban levels can significantly exacerbate bleeding.
Richard Felix Kraus   +6 more
wiley   +1 more source

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