Results 131 to 140 of about 9,695 (195)
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Newer antidotal therapies

Veterinary Clinics of North America: Small Animal Practice, 2002
Although the availability of an antidote for a toxic agent does not take away the primary responsibility of the clinician to manage the patient's clinical signs, the use of antidotes in appropriate situations can result in a more rapid recovery with potentially fewer long-term complications.
Sharon M, Gwaltney-Brant   +1 more
openaire   +2 more sources

Update on Antidotal Therapy

Journal of Pharmacy Practice, 1993
Antidotal therapy is useful for only a meager number of poisonous agents in which reversal of the effects of the toxin, or treatment of the toxin-induced pathophysiologic derangements, is possible. This review of selected antidotes is meant to acquaint the reader with some of the new and/or controversial uses for a few of our older agents, to introduce
Jay L. Schauben, Maureen L. Frenia
openaire   +1 more source

Endocrine effects of organophosphate antidotal therapy

Advances in Therapy, 2004
To determine the endocrine effects of the treatment of organophosphate poisoning, this prospective study was conducted in a university-based emergency department among patients with a history and clinical findings compatible with those of organophosphate poisoning.
Satar S.   +3 more
openaire   +4 more sources

Pharmaceutical Purchasing: a Review of the Landscape and Implications for Antidotal Therapies

Journal of Medical Toxicology, 2023
The management of the poisoned patient often requires the utilization of uncommonly used pharmaceutical interventions. These interventions can be associated with significant costs to both the patient and treating institution. Pharmaceutical supply shortages and issues with accessibility of antidotal therapies complicate the management of many toxic ...
Andrew Troger, Michele M. Burns
openaire   +2 more sources

Nanoencapsulated and microencapsulated enzymes in drug antidotal therapy

Toxicology and Industrial Health, 2011
A catalytic bioscavenger for the therapeutic and prophylactic defense against recognized chemical threat agents has been a long-standing objective of civilian and military research. Among the toxic agents, organophosphate molecules and cyanide have been widely studied.
Szilasi, Mária   +3 more
openaire   +2 more sources

Evolution of Antidotal Therapy in Recent Decades

1997
Antidotes are pharmaceuticals intended to counteract the noxious effects of chemicals, either man-made or of natural origin. They may modify the kinetics of a given toxic substance, its absorption or elimination, reduce its effects on the receptors, and, through different modes of action, ameliorate the functional and vital prognosis of poisonings. The
openaire   +2 more sources

Current Status of Antidotal Therapies in Acute Human Intoxications

Acta Clinica Belgica, 1990
The purpose of this work is a review of usefulness, indications and handling of some antidotes which are at our disposal for therapeutic use since several years, especially naloxone, flumazenil, Fab fragments of digoxin specific antibodies, hydroxocobalamine, 4-methyl-pyrazole, N-acetylcystein or the new metal chelators.
Lheureux, Philippe   +2 more
openaire   +3 more sources

The basis of antidotal therapy

2020
A. Wallace Hayes   +2 more
openaire   +1 more source

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