Results 41 to 50 of about 35,321 (251)

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

open access: yesBMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang   +7 more
wiley   +1 more source

Separate-component-stabilization system for protein and DNA production without the use of antibiotics

open access: yesBioTechniques, 2005
Plasmid instability is a significant concern in the industrial utilization of microorganisms for protein or DNA production. Here we report on the development of a new and highly effective stabilization system based on the use of the ccd antidote/poison ...
Cédric Y. Szpirer   +1 more
doaj   +1 more source

Affect: knowledge, communication, creativity and emotion [PDF]

open access: yes, 2008
Concerns about emotional well-being have recently become the focus of social policy, particularly in education settings. This is a sudden and unique development in placing new ideas about emotion and creativity and communication in curriculum content ...
Ecclestone, Kathryn, Hayes, Dennis
core   +1 more source

Safety, Tolerability, and Pharmacokinetics of GMDTC for Cadmium Poisoning: A Randomized Phase 1a/1b Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Cadmium exposure causes serious health consequences; however, there is no clinically approved antidote for cadmium poisoning. This Phase 1a/1b trial aimed to investigate safety, tolerability, and pharmacokinetics of Sodium (S)‐2‐(dithiocarboxylato((2S,3R,4R,5R)‐2,3,4,5,6‐pentahydroxyhexyl) amino)‐4‐(methylthio) butanoate (GMDTC), a novel chelating ...
Xuefeng Ren   +21 more
wiley   +1 more source

A Meta‐Analysis and Systematic Review of Single‐Session Interventions for Eating Disorders

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Background There is a critical gap between the need for eating disorder (ED) treatment and provider availability. Single‐Session Interventions (SSIs) are structured programs intentionally designed for a single client encounter and show promise for filling ED‐treatment and prevention gaps by enhancing accessibility of evidence‐based ...
Sonakshi Negi   +3 more
wiley   +1 more source

Antidote application: an educational system for treatment of common toxin overdose [PDF]

open access: yes, 2017
Poisonings account for almost 1% of emergency room visits each year. Time is a critical factor in dealing with a toxicologic emergency. Delay in dispensing the first antidote dose can lead to life-threatening sequelae.
Brusic, V.   +4 more
core  

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

open access: yesiNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen   +6 more
wiley   +1 more source

Diagnosis and treatment of persons with acute thallium poisoning

open access: yesToxicology Reports, 2021
Objective: This study aimed to describe organs and systems damages in persons after mass poisoning with thallium and show the results of treatment. Methods: Forty-four persons (12 males and 32 females) with acute oral thallium poisoning were tested for ...
Lesya B. Zavaliy   +11 more
doaj   +1 more source

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz   +3 more
wiley   +1 more source

Encounter, Encounter Groups and the Practicing Physician [PDF]

open access: yes, 1974
Father McEniry explores the various stages of encounter groups and explains the participation process. Physicians who question the value of the movement for their patients will find McEniry\u27s criteria for participation ...
McEniry, Robert
core   +1 more source

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