Pattern of Paracetamol Poisoning: Influence on Outcome and Complications [PDF]
Toxics, 2018 Acute paracetamol poisoning due to a single overdose may be effectively treated by the early administration of N-acetylcysteine (NAC) as an antidote.
Pierre-François Laterre +2 more
exaly +4 more sources
Estimates of Paracetamol Poisoning in Brazil: Analysis of Official Records From 1990s to 2020 [PDF]
Frontiers in Pharmacology, 2022 Objective: To assess the cases of paracetamol poisoning in Brazil. Methods: Analysis of official records of deaths between 1996 and 2019 from the Brazil Mortality Information System (SIM), admissions between 2008 and 2020 from the Hospital Information ...
Okuyama JHH, Galvao TF, Silva MT
doaj +2 more sources
A comprehensive overview of paracetamol poisoning admissions and long-term outcomes in New South Wales, Australia: a retrospective linked data cohort (PAVLOVA-3)Research in context [PDF]
The Lancet Regional Health. Western PacificSummary: Background: Paracetamol poisoning is a major public health issue and a leading cause of acute liver failure. Population-level data on outcomes, repetition, and long-term survival remain limited. This study characterises hospitalised paracetamol
Annabelle S. Chidiac +8 more
doaj +2 more sources
Clinical characteristics and outcomes of pediatric paracetamol poisoning presenting to the emergency department [PDF]
BMC PediatricsBackground Paracetamol is one of the most widely used analgesic and antipyretic medications in children. Although it is considered safe at therapeutic doses, its widespread availability and low cost increase the risk of overdose and poisoning.
Bihter Karabacak, Eda Özaydın
doaj +2 more sources
Therapeutic effect of WGO in reducing the toxic effect of paracetamol on blood cells and hepato-nephro activity in male rats [PDF]
Open Veterinary JournalBackground: Paracetamol (also called acetaminophen) overdose induces hepatotoxicity that can lead to liver failure. Liver poisoning occurs as a result of paracetamol poisoning when a toxic dose of paracetamol is taken, as the liver loses the ability to ...
Moayad Mijbil Ubaid +3 more
doaj +2 more sources
Assessing the Effect of Leptin on Liver Damage in Case of Hepatic Injury Associated with Paracetamol Poisoning [PDF]
Gastroenterology Research and Practice, 2015 Background Aim. In case of high-dose acetaminophen intake, the active metabolite can not bind to the glutathione, thereby inducing cellular necrosis through binding to the cytosol proteins.
Murat Polat +6 more
doaj +2 more sources
Haemodialysis in acute paracetamol poisoning. [PDF]
BMJ Case Rep, 2017 A woman aged 23 years presented late with clinical and biochemical features of a life-threatening paracetamol (acetaminophen) overdose. Despite instigating N-acetylcysteine treatment, due to evidence of mitochondrial dysfunction together with an exceedingly high paracetamol level, the decision was made to dialyse the patient acutely to remove the ...
Serjeant L +3 more
europepmc +4 more sources
Parental awareness and practices regarding paracetamol use in children: A cross-sectional study from Pakistan. [PDF]
PLOS Global Public HealthParacetamol is the one of the most widely administered drug as an analgesic and antipyretic due to its efficacy, safety, and over-the-counter (OTC) nature and is present in various pharmaceutical forms.
Muhammad Saad Nadeem Butt, Sana Shah
doaj +2 more sources
Keracunan Parasetamol Pada Kucing Dan Anjing: Gejala Klinis dan Terapi
Jurnal Ilmu Peternakan dan Veteriner Tropis, 2020 Acetaminophen, commonly known as paracetamol, is a non-steroidal anti-inflammatory drug commonly used in human medicine for its antipyretic and analgesic action.
Yanuartono Yanuartono +5 more
doaj +3 more sources
On the Treatment of Acute Poisoning With Paracetamol
Неотложная медицинская помощь, 2022 BACKGROUND Currently, despite the optimization of diagnostic methods in order to predict the development of liver damage, improvement of treatment protocols, paracetamol poisoning is a serious problem in medicine, being the most common cause of acute ...
A. Yu. Simonova +6 more
doaj +1 more source