Results 41 to 50 of about 117,311 (162)

Metabolic profiling of body fluids by proton NMR: self-poisoning episodes with paracetamol (acetaminophen)

open access: yes, 1988
1H NMR spectra of urine and plasma from subjects who had taken paracetamol (acetaminophen) at a therapeutic dose or in self-poisoning episodes (both fatal and nonfatal) are compared. They provide convenient metabolic profiles. For overdose cases, intense
Sadler, P.J.   +7 more
core   +1 more source

Use of Intralipid Therapy and Therapeutic Plasma Exchange in the Management of Cholecalciferol Rodenticide Exposure in a Dog: A Case Report

open access: yesJournal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To describe the presentation and outcome of a case of suspected cholecalciferol rodenticide intoxication managed with both intralipid emulsion (ILE) and therapeutic plasma exchange (TPE). Case Summary A 3‐year‐old, neutered female, crossbreed dog presented for acute‐onset vomiting and lethargy after suspected exposure to ...
Tanvi A. Kamat   +3 more
wiley   +1 more source

Acute kidney injury in a dog after ingestion of homemade modelling dough containing cream of tartar (potassium bitartrate)

open access: yesVeterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Summary A 16‐month‐old, male, neutered cocker spaniel developed gastrointestinal signs following ingestion of a homemade modelling dough containing cream of tartar. Blood biochemistry (29 hours post‐ingestion) showed elevated creatinine, urea and symmetric dimethylarginine (SDMA).
Fiona Adam, Nicola Bates
wiley   +1 more source

High Doses of N‐Acetyl‐P‐Aminophenol Cause Acute Changes in Electroencephalographic and Electrocardiographic Activities in Wistar Rats

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 5, November 2026.
ABSTRACT N‐acetyl‐p‐aminophenol (APAP), or acetaminophen, is the most prescribed analgesic and antipyretic, even used in association with other drugs. Because it is easily bought in drugstores, much evidence about its toxic effects is known due to high doses or continuous use, which can lead to death in cases of intoxication.
Alex Luiz Menezes da Silva   +9 more
wiley   +1 more source

A Quantitative Analysis of Street‐Level Drugs Seized in New South Wales, Australia: Purity, Dose and Adulterants

open access: yesDrug and Alcohol Review, Volume 45, Issue 7, November 2026.
ABSTRACT Introduction The Combined Surveillance and Monitoring of Seized Samples (CoSMoSS) program is a joint harm reduction initiative between NSW Health and NSW Police Force. Here, we examine the contents and purity of a sample of seized suspected target drugs (cocaine, heroin, methamphetamine and 3,4‐methylenedioxymethamphetamine ‘MDMA’).
Janette L. Smith   +7 more
wiley   +1 more source

Evaluating Harm Reduction Advice From Large Language Models

open access: yesDrug and Alcohol Review, Volume 45, Issue 7, November 2026.
ABSTRACT Introduction Large language models (LLM) and generative Artificial Intelligence are increasingly providing health information. We have applied a novel method to evaluate the harm reduction information generated by popular LLMs. We focused on the filtration of oral medications for injection and the availability of local harm reduction services.
Khy Choo   +3 more
wiley   +1 more source

Iron and Other Metal Ions in Human Health and Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Multi-centre Implementation of the SNAP Protocol for Paracetamol Overdose - reducing the length of stay

open access: yesSaudi Journal of Emergency Medicine
Aim/Objective/Background: Paracetamol stands as one of the most prevalent drugs of overdose in the UK. The conventional treatment for Paracetamol toxicity involves intravenous administration of N-acetylcysteine (NAC), typically administered over 21 ...
Roshan Joseph   +3 more
doaj   +1 more source

Knowledge and practices of paracetamol administration among caregivers of pediatric age group patients

open access: yesJournal of Family Medicine and Primary Care, 2012
Introduction: Paracetamol is a widely used over the counter drug for pyrexia and mild to moderate pain in all age groups. Objective: To assess the knowledge and practices of paracetamol administration among caregivers of the pediatric age group patients ...
R.P.J.C. Ramanayake   +4 more
doaj   +1 more source

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