Results 31 to 40 of about 117,311 (162)

An open-label randomized clinical trial of prophylactic paracetamol coadministered with 7-valent pneumococcal conjugate vaccine and hexavalent diphtheria toxoid, tetanus toxoid, 3-component acellular pertussis, hepatitis B, inactivated poliovirus, and Haemophilus influenzae type b vaccine [PDF]

open access: yes, 2013
BACKGROUND: In two clinical trials, low-grade fever was observed more frequently after coadministration than after separate administration of two recommended routine pediatric vaccines.
Rose, Markus A.   +11 more
core   +2 more sources

Pattern of food, drug and chemical poisoning in Qassim region, Saudi Arabia from January 2017 to December 2017

open access: yesToxicology Reports, 2020
Background: Poisoning has become a widespread and dangerous phenomenon worldwide. The purpose of our study was to determine and analyze the pattern of poisoning cases induced with food, drugs, and chemicals reported to the Department of Environmental and
Sulaiman Alnasser   +3 more
doaj   +1 more source

Anual Evaluation of “Drug Poisonings, Emergency Service” Studies Published in Pubmed 01.01.2019-01.01.2020

open access: yesEurasian Journal of Emergency Medicine, 2021
Aim:This study aimed to evaluate studies on drug poisoning and emergency servics published in PubMed between January 2019 and January 2020.Materials and Methods:The literature review was carried out using the terms “drug poisoning and emergency medicine”
İ. Hamit Hancı, Neslihan Gürbüz
doaj   +1 more source

N‐acetylcysteine for non‐paracetamol‐induced acute liver failure in children: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Non‐surgical treatment of acute liver failure (ALF) is primarily supportive and depends on the underlying cause. While N‐acetylcysteine (NAC) is proven effective in paracetamol‐induced ALF, its potential benefits in non‐paracetamol ALF for paediatric patients remain unclear.
Alise D. E. de Groot   +7 more
wiley   +1 more source

NQO2 is a reactive oxygen species generating off-target for acetaminophen [PDF]

open access: yes, 2014
The analgesic and antipyretic compound acetaminophen (paracetamol) is one of the most used drugs worldwide. Acetaminophen overdose is also the most common cause for acute liver toxicity.
Teemu P. Miettinen   +3 more
core   +1 more source

Prediction of Acute Liver Injury Trajectory in Patients Following Acetaminophen Overdose: A Multibiomarker Machine Learning Proof‐of‐Concept Study

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries   +8 more
wiley   +1 more source

Intoxicação e exposições por paracetamol: análise de seis anos de registros de Centro de Informações Toxicológicas de Santa Catarina - CIT/SC. [PDF]

open access: yes, 2007
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Schuh, Diego Callai
core  

A Study of Pharmaceutical Drugs Poisoning Cases Admitted to the National Poisoning Center, Kasralainy Teaching Hospital in Cairo

open access: yesEurasian Journal of Emergency Medicine, 2020
Aim:There is a necessity to identify the specific therapeutic drugs most frequently responsible for the acute medicinal poisoning to take up appropriate preventive efforts and management.Materials and Methods:This study included all cases of medicinal ...
Eman Abdel Monem Abdel Rasheed   +4 more
doaj   +1 more source

The Prophylactic Anti-Inflammatory Effect of Omega-7 Against Paracetamol-Induced Liver Injury in Rats

open access: yesThe Iraqi Journal of Veterinary Medicine, 2022
Paracetamol poisoning, whether intentionally or accidentally, is one of the main public health problems since the prevalence of its toxicity increased significantly in many countries.
Hadeel A Hameed, Ali F Hassan
doaj   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

open access: yesVIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe   +8 more
wiley   +1 more source

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