Results 11 to 20 of about 117,311 (162)

On the Treatment of Acute Poisoning With Paracetamol

open access: yesНеотложная медицинская помощь, 2022
BACKGROUND Currently, despite the optimization of diagnostic methods in order to predict the development of liver damage, improvement of treatment protocols, paracetamol poisoning is a serious problem in medicine, being the most common cause of acute ...
A. Yu. Simonova   +6 more
doaj   +2 more sources

Interrupted time-series analysis of regulations to reduce paracetamol (acetaminophen) poisoning. [PDF]

open access: yesPLoS Medicine, 2007
BackgroundParacetamol (acetaminophen) poisoning is the leading cause of acute liver failure in Great Britain and the United States. Successful interventions to reduced harm from paracetamol poisoning are needed.
Oliver W Morgan   +2 more
doaj   +2 more sources

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

open access: yesHepatology, EarlyView., 2022
CHIN117 is a dual cysteinyl leukotriene receptor 1 (CYSLTR1) antagonist and G‐protein‐coupled bile acid receptor 1 (GPBAR1) agonist. In the liver, GPBAR1 and CYSLTR1 are coexpressed by liver sinusoidal endothelial cells (LSECs), HSCs, circulating monocytes/macrophages, and liver resident macrophages (Kupffer cells).
Michele Biagioli   +13 more
wiley   +1 more source

Potential deleterious effects of paracetamol dose regime used in Nigeria versus that of the United States of America

open access: yesToxicology Reports, 2022
Paracetamol, also known as acetaminophen (N-acetyl-para-aminophenol, APAP) is the world’s most used over-the-counter analgesic-antipyretic drug. Despite its good safety profile, acetaminophen can cause severe hepatotoxicity in overdose, and poisoning ...
Samuel James Offor   +4 more
doaj   +1 more source

Acute paracetamol poisonings received at the Oran University Hospital

open access: yesToxicology Reports, 2020
Introduction: Paracetamol is the most commonly used drug worldwide for its analgesic/antipyretic effect and especially a non-prescription access in pharmacies.
Bilel Chefirat   +4 more
doaj   +1 more source

Comparative evaluation of the effectiveness and safety of 12-hour and 21-hour protocols for the administration of acetylcysteine in paracetamol poisoning

open access: yesВестник анестезиологии и реаниматологии, 2023
Background. Acetylcysteine (ACC) is an effective antidote for paracetamol poisoning. There are various schemes for its application. At the same time, there is currently no information about the most priority of them in this pathology.
A. Yu. Simonova   +5 more
doaj   +1 more source

Successful management of delayed presentation of massive paracetamol overdose in a resource‐limited setting: A case report from Nepal

open access: yesClinical Case Reports, 2022
We present a case of self‐poisoning with a massive dose of paracetamol by a young Nepalese female patient who presented late to our emergency department.
Pratik Lamichhane   +5 more
doaj   +1 more source

Adverse effects of paracetamol

open access: yesJournal of Education, Health and Sport, 2017
Admission. Paracetamol (acetaminophen) is one of the most popular medicinal substances in the world, characterized by analgesic and antipyretic properties. This pharmacy is issued without a prescription and can be purchased not only in pharmacies.
Michał Konopelko   +4 more
doaj   +3 more sources

Paracetamol poisoning and its treatment in man [PDF]

open access: yes, 2008
Paracetamol is the most common drug taken in overdose in the UK. Although it has been used in overdose for about 50 years, there are many aspects of its toxicity and treatment that are not fully understood.
Pakravan, Nasrin
core   +3 more sources

Urine ‘picket fence’ crystals in ethylene glycol poisoning

open access: yesAfrican Journal of Nephrology, 2021
A 46-year-old woman intentionally ingested ethylene glycol and overdosed on paracetamol. She had clinical and laboratory features suggestive of ethylene glycol poisoning, and examination of the urine revealed calcium oxalate monohydrate, or ‘picket fence’
Mogamat-Yazied Chothia, Nabeel Bapoo
doaj   +1 more source

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