Results 121 to 130 of about 22,164 (248)

Antiemesis Corticosteroids Potentiate Checkpoint Blockade Efficacy by Normalizing the Immune Microenvironment in Metastatic Murine Breast Cancer

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Corticosteroids improve the efficacy of immune checkpoint blockade therapy in metastatic murine breast cancer. By normalizing the tumor immune microenvironment, corticosteroids reduce immunosuppressive signals, restore T‐cell function, and promote antitumor immune responses, resulting in enhanced tumor control.
John D. Martin, Koji Nagaoka, Myrofora Panagi, Akihiro Hosoi, Fotios Mpkeris, Pengwen Chen, Thahomina T. Khan, Margaret R. Martin, Changbo Sun, Chrysovalantis Voutouri, Maria Louca, Panagiotis Papageorgis, Akira Sumiyoshi, Nobuhiro Nitta, Kazuyoshi Takeda, Ichio Aoki, Kazunori Kataoka, Triantafyllos Stylianopoulos, Kazuhiro Kakimi, Horacio Cabral   +19 more
wiley   +1 more source

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Dexamethasone-sparing strategies in anthracycline and cyclophosphamide-based chemotherapy with a focus on 5-HT3 receptor antagonists: a network meta-analysis

Frontiers in Oncology
BackgroundThe effectiveness of a dexamethasone-sparing strategy in the treatment of breast cancer with anthracycline-cyclophosphamide therapy when combined with first-generation 5-HT3 receptor antagonists (RAs) and neurokinin-1 RAs is unclear.
Daichi Watanabe, Daichi Watanabe, Hirotoshi Iihara, Hirotoshi Iihara, Hirotoshi Iihara, Ryo Kobayashi, Ryo Kobayashi, Hironori Fujii, Ryutaro Mori, Keisuke Kumada, Keisuke Kumada, Masahito Shimizu, Masahito Shimizu, Manabu Futamura, Akio Suzuki, Akio Suzuki   +15 more
doaj   +1 more source

Safe Driving for the Mature Adult: Selected Issues [PDF]

, 2017
Educational Objectives 1. Examine issues related to aging and driving assessment. 2. Review Virginia’s Mature Drivers Study. 3. Discuss the levels of care for prevention of driving disability and resources available at each level. 4.
Parsio, Rebecca
core   +1 more source

Long‐Term Survival Outcomes of Concurrent Chemoradiotherapy for Postoperative High‐Risk Salivary Gland Carcinomas

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background This study evaluated the long‐term survival outcomes of concurrent chemoradiation (CCRT) for high‐risk salivary gland carcinomas (SGCs). Method Postoperative patients with high‐risk SGCs, other than adenoid cystic carcinoma (ACC), with T3‐4/N1‐3M0 disease were enrolled.
Shengjin Dou, Xin Wang, Lin Zhang, Wen Jiang, Lulu Ye, Yu Wang, Rongrong Li, Guopei Zhu   +7 more
wiley   +1 more source

Evaluating the antiemetic administration consistency to prevent chemotherapy-induced nausea and vomiting with the standard guidelines: a prospective observational study

Therapeutics and Clinical Risk Management, 2017
Afsaneh Vazin, Davood Eslami, Ebrahim Sahebi Department of Clinical Pharmacy, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran Abstract: Nausea and vomiting (NV) are the most prevalent adverse effects of chemotherapy (CT).
Vazin A, Eslami D, Sahebi E
doaj  

Metoclopramide‐Induced Pheochromocytoma Crisis: A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Pheochromocytoma is a catecholamine‐secreting neuroendocrine tumor originating in the adrenal medulla. In patients with pheochromocytoma, paroxysmal over‐secretion of catecholamines can be triggered by various medications, including the commonly used antiemetic metoclopramide.
Yuki Yamanishi, Kazuki Iio, Keiki Shimizu, Wataru Kasahara, Jun Hamaguchi   +4 more
wiley   +1 more source

Novel therapies for nausea and vomiting in advanced illness and supportive cancer care

Palliative Care and Social Practice
Nausea and vomiting are common experiences and are often dreaded more than pain. This review discusses blonanserin, mirtazapine, and isopropyl alcohol as antiemetics.
Mellar P. Davis
doaj   +1 more source

Case Report of Acute Severe Hyponatremia Induced by Desmopressin Administration During Chemotherapy

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Patients undergoing chemotherapy are prone to developing hyponatremia due to insufficient oral intake because of nausea and vomiting, administration of large volumes of intravenous fluids, syndrome of inappropriate antidiuretic hormone secretion induced by chemotherapeutic agents, adrenal insufficiency, and drug interactions.
Koutaro Ono, Shugo Uematsu, Aya Yoshihara, Ayako Tsuboya, Shoichi Mori, Takashi Yoshioka, Shuichi Nawata   +6 more
wiley   +1 more source

Complementary and Alternative Medicine in Oncology: A Concise Review of Utilization, Evidence, and Integration Challenges

Cancer Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Complementary and alternative medicine (CAM) is widely used by cancer patients and increasingly shapes oncological care worldwide. This narrative review examines current evidence on utilization patterns, theoretical frameworks, clinical efficacy, and safety aspects of CAM in oncology.
Danica Schöneseiffen, Matthias B. Stope
wiley   +1 more source