Pediatric Anesthesia, Volume 35, Issue 7, Page 552-561, July 2025.ABSTRACT Background Posterior spinal instrumentation and fusion is a common surgical correction for adolescent idiopathic scoliosis. Preventative multimodal analgesia, including opioids, is required to minimize postoperative pain, but opioids are associated with dose‐dependent side effects that may disrupt recovery.
Jessica Luo +8 more
wiley +1 more source
Pigment Cell &Melanoma Research, Volume 38, Issue 4, July 2025.ABSTRACT The unique pharmacokinetics of BRAF and MEK inhibitors make patients vulnerable to drug–drug interactions (DDIs), which may compromise treatment efficacy in metastatic melanoma. This study evaluates the impact of DDIs on clinical outcomes in patients with metastatic melanoma treated with BRAF/MEK inhibitors.
Silvia Mezi +14 more
wiley +1 more source
Therapeutics and Clinical Risk Management, 2017 Afsaneh Vazin, Davood Eslami, Ebrahim Sahebi Department of Clinical Pharmacy, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran Abstract: Nausea and vomiting (NV) are the most prevalent adverse effects of chemotherapy (CT).
Vazin A, Eslami D, Sahebi E
doaj
Phase II study of pregabalin for the prevention of chemotherapy induced nausea and vomiting
O Mundo da SaúdeTo evaluate the role of pregabalin in the protection of chemotherapy-induced nausea and vomiting, we performed a phase II randomized, double-blind, placebo-controlled trial to investigate whether pregabalin could improve the complete control of nausea ...
Carla Santos Rossi Paniquar +3 more
doaj +1 more source
Is ondansetron a less effective antiemetic against moderately emetic as compared with highly emetic chemotherapy? [see comments] [PDF]
, 1992 JW Dundee +3 more
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Medicines management in the palliative care of cancer patients [PDF]
, 2015 Cancer is one of the leading causes of death in Malta. Palliative care is a mainstay in the care of such patients. Commonly encountered symptoms include pain, nausea and vomiting, constipation and oropharyngeal complications.
Mifsud, Ian, Vella Bonanno, Patricia
core
Are more antiemetic trials with a placebo necessary? Report of patient data from randomized trials of placebo antiemetics with cisplatin [PDF]
, 1996 Mark G. Kris +6 more
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ATHENA: A Phase 3, Open-Label Study Of The Safety And Effectiveness Of Oliceridine (TRV130), A G-Protein Selective Agonist At The µ-Opioid Receptor, In Patients With Moderate To Severe Acute Pain Requiring Parenteral Opioid Therapy. [PDF]
, 2019 Background:Pain management with conventional opioids can be challenging due to dose-limiting adverse events (AEs), some of which may be related to the simultaneous activation of β-arrestin (a signaling pathway associated with opioid-related AEs) and G ...
Beard, Timothy L +10 more
core
Antiemetic Efficacy of Ondansetron After Outpatient Laparoscopy
, 1991 Matthew Bodner, Paul F. White
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Computer Library Literature Review on Effectiveness of Antimotion Sickness Drugs [PDF]
Physiological responses to antimotion sickness drugs - antihistamines, belladonnas, and ...
Graybiel, A. +4 more
core +1 more source