Results 51 to 60 of about 17,876 (257)

Current practice and guideline adherence in renal dose adjustment for patients with chronic kidney disease: A systematic review and meta‐analysis

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed   +7 more
wiley   +1 more source

Effect of modified rapid sequence induction on postoperative nausea and vomiting in patients undergoing gynecologic laparoscopic surgery - A randomized controlled trial

open access: yesJournal of Anaesthesiology Clinical Pharmacology
Background and Aims: The incidence of postoperative nausea and vomiting (PONV) ranges between 30% and 80%, and face mask ventilation (FMV) prior to intubation may be a significant risk factor.
R. Afshan   +5 more
doaj   +1 more source

NEPA, a new fixed combination of netupitant and palonosetron, is a cost-effective intervention for the prevention of chemotherapy-induced nausea and vomiting in the UK

open access: yesDrugs in Context, 2017
Background: The objective was to evaluate the cost-effectiveness of NEPA, an oral fixed combination netupitant (NETU, 300 mg) and palonosetron (PA, 0.5 mg) compared with aprepitant and palonosetron (APPA) or palonosetron (PA) alone, to prevent ...
Helene Cawston   +7 more
doaj   +1 more source

Acute effects of THC and a CBD+THC combination on cardiovascular haemodynamics and respiratory muscle activity during loaded breathing in healthy adults: A randomized placebo‐controlled crossover study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the acute effects of cannabidiol plus tetrahydrocannabinol (CBD+THC) and tetrahydrocannabinol (THC) oils on cardiovascular haemodynamics, respiratory muscle activity and peripheral tissue perfusion in healthy adults. Methods In this randomized, double‐blind, crossover trial, participants received orally administered ...
Edna Karla Ferreira Laurentino   +9 more
wiley   +1 more source

Diabetic gastroparesis: current challenges and future prospects

open access: yesClinical and Experimental Gastroenterology, 2018
Danny J Avalos,1 Irene Sarosiek,1 Priyadarshini Loganathan,2 Richard W McCallum1 1Division of Gastroenterology, Center for Neurogastroenterology and GI Motility, Texas Tech University Health Sciences Center, El Paso, TX, USA; 2Department of Internal ...
Avalos DJ   +3 more
doaj  

Repurposing the Antiemetic Metoclopramide as an Antiviral Against Dengue Virus Infection in Neuronal Cells

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Dengue virus (DENV) is transmitted by Aedes mosquitoes to humans and is a threat worldwide. No effective new drugs have been used for anti-dengue treatment, and repurposing drugs is an alternative approach to treat this condition.
Ting-Jing Shen   +14 more
doaj   +1 more source

Cancer therapy, vomiting, and antiemetics

open access: yes, 1990
Both radiotherapy and chemotherapy for cancer are capable of causing nausea and vomiting. With both treatment modalities, the nausea and vomiting is thought to be a second-order process rather than being due to direct stimulation of neuromechanisms that
David J. Stewart
core   +1 more source

Antiemetics Commonly Prescribed in Children Undergoing Dental Treatment Under General Anaesthesia- A Retrospective Cohort Study [PDF]

open access: yes, 2023
Background: Postoperative nausea and vomiting (PONV) are the most widely recognized unfavorable impact of pediatric anaesthesia and medical procedure Numerous antiemetic drugs are utilized for preventive treatment.
Govindaraju, Dr. Lavanya   +1 more
core   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Bioequivalence of HTX-019 (aprepitant IV) and fosaprepitant in healthy subjects: a Phase I, open-label, randomized, two-way crossover evaluation

open access: yesDrug Design, Development and Therapy, 2018
Tom Ottoboni,1 Mary Rose Keller,2 Matt Cravets,3 Neil Clendeninn,4 Barry Quart5 1Pharmaceutical and Translational Sciences, Heron Therapeutics, Inc., San Diego, CA, USA; 2Clinical Operations, Heron Therapeutics, Inc., San Diego, CA, USA; 3Biometrics ...
Ottoboni T   +4 more
doaj  

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