Metoclopramide in Gastroparesis: Its Mechanism of Action and Safety Profile
Metoclopramide has been the cornerstone of gastroparesis management for the past 40 years as it is the only FDA-approved medication for gastroparesis. Other medications such as erythromycin and domperidone have been used off-label with variable efficacy.
M Ammar Kalas +4 more
doaj +2 more sources
Metoclopramide neurological side effects screening; a pharmacovigilence study in Romanian community pharmacies [PDF]
Background. Metoclopramide is a pharmacological agent frequently used in therapy against nausea and vomiting that can occur in indigestion, motion sickness, gastric ulcer, pyloric spasm and after surgery as a side effect of some anesthetics.
Emil Ștefănescu +4 more
doaj +5 more sources
Objectives: One of the irritating features of migraine is emesis that can compromise taking oral medications. We designed this study to compare the effectiveness of granisetron and metoclopramide in reducing pain and treating emesis in migraine patients.
Hassan Amiri +4 more
doaj +2 more sources
Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study [PDF]
Nausea is a subjective sensation which is difficult to measure in non-verbal species. The aims of this study were to determine the efficacy of three classes of antiemetic drugs in a novel low dose cisplatin model of nausea and vomiting and measure change
A Freeman +47 more
core +2 more sources
Metoclopramide-Induced Pheochromocytoma Crisis: A Case Report and Literature Review. [PDF]
Pheochromocytoma is a catecholamine‐secreting neuroendocrine tumor originating in the adrenal medulla. In patients with pheochromocytoma, paroxysmal over‐secretion of catecholamines can be triggered by various medications, including the commonly used ...
Yamanashi Y +4 more
europepmc +2 more sources
Effects of metoclopramide on the expression of metalloproteinases and interleukins in left colonic anastomoses. An experimental study [PDF]
PURPOSE : To evaluate the effects of metoclopramide on metalloproteinases (MMP) and interleukins (IL) gene expression in colonic anastomoses in rats. METHODS : Eighty rats were divided into two groups for euthanasia on the 3rd or 7th postoperative day ...
Silvana Marques e Silva +5 more
doaj +6 more sources
Metoclopramide or domperidone improves post-pyloric placement of spiral nasojejunal tubes in critically ill patients: a prospective, multicenter, open-label, randomized, controlled clinical trial [PDF]
IntroductionThe use of prokinetic agents on post-pyloric placement of spiral nasojejunal tubes is controversial. The aim of the present study was to examine if metoclopramide or domperidone can increase the success rate of post-pyloric placement of ...
Bei Hu +17 more
core +2 more sources
Efficacy and safety of peripheral magnetic stimulation for the treatment of intractable hiccups after stroke: a prospective, blinded, parallel randomized controlled clinical trial. [PDF]
AimsPreclinical studies indicate that magnetic stimulation may be an efficacious treatment for intractable hiccups in post-stroke patients. This study aimed to investigate repetitive peripheral magnetic stimulation (rPMS) potential efficacy and safety ...
Liu Q +7 more
europepmc +2 more sources
Pediatric Emergency Service Admissions due to Acute Dystonic Reaction Induced by Metoclopramide
Objective: Metoclopramide is a dopamine receptor antagonist. It is not routinely recommended in children, particularly because of its extrapyramidal side effects.
Gülşen YALÇIN, Murat ANIL
doaj +1 more source

