Results 1 to 10 of about 1,859 (175)

Rikkunshito as a Therapeautic Agent for Functional Dyspepsia and its Prokinetic and Non-Prokinetic Effects [PDF]

open access: yesFrontiers in Pharmacology, 2021
Prokinetics is one of the therapeutic agents for functional and motility disorders of the stomach. However, its efficacy is limited. Kampo medicine is a unique medical system that was developed in Japan.
Takanori Kanai
exaly   +5 more sources

Augmented Oral Bioavailability and Prokinetic Activity of Levosulpiride Delivered in Nanostructured Lipid Carriers

open access: yesPharmaceutics, 2022
The present study is aimed to develop and optimize levosulpiride-loaded nanostructured lipid carriers (LSP-NLCs) for improving oral bioavailability and prokinetic activity of LSP.
Shahiq Uz Zaman   +2 more
exaly   +4 more sources

Prokinetic Agents [PDF]

open access: yesThe Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2022
Gastrointestinal (GI) prokinetic agents are drugs that increase GI motility and promote the movement of contents in the GI tract by amplifying and controlling the contraction of GI smooth muscle.
Hyo Yeop Song   +2 more
doaj   +2 more sources

The Pharmacology of TD-8954, a Potent and Selective 5-HT4 Receptor Agonist with Gastrointestinal Prokinetic Properties

open access: yesFrontiers in Pharmacology, 2011
This study evaluated the in vitro and in vivo pharmacological properties of TD-8954, a potent and selective 5-HT4 receptor agonist. TD-8954 had high affinity (pKi = 9.4) for human recombinant 5-HT4(c) (h5-HT4(c)) receptors, and selectivity (> 2,000 ...
David T Beattie
exaly   +3 more sources

Does ranitidine administration improve gastrointestinal hypomotility in dogs?

open access: yesVeterinary Evidence, 2021
PICO question In dogs presenting with gastrointestinal (GI) hypomotility is ranitidine administration (any route) beneficial in improving GI motility?   Clinical bottom line Category of research question Treatment The number and type of
Lara Brunori
doaj   +1 more source

Retrospective study on the use of lidocaine constant rate infusions for the treatment of ileus in ruminants and camelids

open access: yesJournal of Veterinary Internal Medicine, 2021
Limited knowledge exists regarding the use of lidocaine as a prokinetic in ruminants and camelids to treat gastrointestinal ileus. In this retrospective study, ruminant and camelid cases diagnosed with ileus and treated with a lidocaine constant rate of ...
Katie Yau   +3 more
doaj   +1 more source

THE PROKINETIC EFFECT OF ITOPRIDE, A COMPARATIVE STUDY WITH METOCLOPRAMIDE [PDF]

open access: yesAl-Azhar Journal of Pharmaceutical Sciences, 2015
The motor function of GIT can be modulated by prokinetics or myorelaxant drugs depending on the nature of the disorder. There is a frequent need for facilitation of gastric emptying in treatment of functional dyspepsia.
Elsayed Kamel
doaj   +1 more source

COMPARISON OF PROKINETIC ACTIVITY OF RANITIDINE AND NEOSTIGMINE ALONE AND IN COMBINATION- AN IN VITRO STUDY

open access: yesPakistan Armed Forces Medical Journal, 2021
Objective: To explore the prokinetic effect of Ranitidine, to compare it with the prokinetic effect of Neostigmine and to observe the potentiating prokinetic effect of Ranitidine and Neostigmine in combination.
Aroosa Ishtiaq Butt   +4 more
doaj   +1 more source

Laxative effect of bitter almond (Amygdalus communis var. amara) [PDF]

open access: yesThe Iranian Journal of Veterinary Science and Technology, 2014
Thepossible laxative and prokinetic effects of bitter almond were studied: 1- two groups of 7 rats were gavaged with ethanol extract of bitter almond (500mg/kg) or placebo and the number of feces, fecal weight and its percentage of water were studied 18 ...
Hamid Reza Kazrani, Seddigheh Jalali
doaj   +1 more source

Herbal combination 'HAGE-101912' Ameliorates gastroesophageal reflux disease in rats

open access: yesJournal of Pharmacy and Bioallied Sciences, 2023
Background: Gastroesophageal reflux disease (GERD) is a chronic, relapsing disorder. In this era of modern and fast-track lifestyle and food habits, the incidence of GERD is rapidly increasing.
Mohammed M Azeemuddin   +5 more
doaj   +1 more source

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