Results 1 to 10 of about 106,580 (245)

Overprescribing proton pump inhibitors [PDF]

open access: yesBMJ, 2008
Proton pump inhibitors are one of the most frequently prescribed classes of drug in the world because they combine a high level of efficacy with low toxicity. In 2006, expenditure on these drugs was £425m (€595m; $872m) in England1 and £7bn globally.2 Yet studies consistently show that proton pump inhibitors are being overprescribed worldwide in both ...
Ian, Forgacs, Aathavan, Loganayagam
openaire   +2 more sources

Proton pump inhibitors are associated with increased risk of development of chronic kidney disease [PDF]

open access: yes, 2016
Background Acute interstitial nephritis secondary to proton pump inhibitors (PPIs) frequently goes undiagnosed due to its subacute clinical presentation, which may later present as chronic kidney disease (CKD).
Arora, Pradeep   +6 more
core   +2 more sources

Proton pump inhibitors

open access: yesWorld Chinese Journal of Digestology, 2013
Proton pump inhibitors (PPIs), omeprazole, lansoprazole, pantoprazole, rabeprazole, esomeprazole, and dexlansoprazole bind irreversibly to the H+, K+- ATPase (the “proton pump”) inhibiting its activity and decreasing gastric acid production.
Jie-Hao Zhou, Bing-Rong Liu
openaire   +2 more sources

Knowledge-based best of breed approach for automated detection of clinical events based on German free text digital hospital discharge letters [PDF]

open access: yes, 2019
OBJECTIVES: The secondary use of medical data contained in electronic medical records, such as hospital discharge letters, is a valuable resource for the improvement of clinical care (e.g. in terms of medication safety) or for research purposes. However,
Demuth, Ilja   +4 more
core   +1 more source

Chronic cough and esomeprazole: A double-blind placebo-controlled parallel study [PDF]

open access: yes, 2011
Background and objective: Gastro-oesophageal reflux has been implicated in the pathogenesis of chronic cough. Guidelines on management suggest a therapeutic trial of anti-reflux medication.
Beecher   +41 more
core   +1 more source

Practical Strategies for Pharmacist Integration with Primary Care: A Workbook. [PDF]

open access: yes, 2014
This workbook is a practical set of tips and resources to assist pharmacists in providing clinical pharmacy services to primary care providers and their patients.
Biddle, Michael A, Kennedy, Amanda G
core   +2 more sources

Structures and proton-pumping strategies of mitochondrial respiratory enzymes [PDF]

open access: yes, 2001
Enzymes of the mitochondrial respiratory chain serve as proton pumps, using the energy made available from electron transfer reactions to transport protons across the inner mitochondrial membrane and create an electrochemical gradient used for the ...
Chan, Sunney I., Schultz, Brian E.
core   +1 more source

Proton Pump Inhibitors [PDF]

open access: yesGut, 2000
Proton Pump Inhibitors . Edited by Olbe L. (Pp 264; illustrated; sFr198.00.) Switzerland: Birkhauser Verlag. 1999. ISBN 3 76435 897 1. The history of the development of drugs to treat the so-called acid related diseases makes a fascinating story, and the publication of this book addresses a significant chapter in that story.
openaire   +3 more sources

Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain [PDF]

open access: yes, 2017
BACKGROUND: Cross-sectional studies suggest that the microbes in the human gut have a role in obesity by influencing the human body's ability to extract and store calories.
A.M. Valdes   +5 more
core   +3 more sources

Nonesophageal Eosinophilic Gastrointestinal Disorders: Clinical Care and Future Directions [PDF]

open access: yes, 2018
Eosinophilic gastrointestinal disorders are a set of conditions with a wide range of clinical manifestations and treatment modalities. The disorders are suspected to result from an abnormal inflammatory response to allergen(s), and individuals may ...
Gupta, Sandeep K., Naramore, Sara
core   +1 more source

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