Results 1 to 10 of about 62,447 (255)
Deprescribing proton pump inhibitors
Kim Jun Kevin Teh +3 more
doaj +3 more sources
Proton-pump inhibitors (PPIs) are a class of drugs that profoundly suppress gastric acid secretion, and thus have become the treatment of choice for gastro-oesophageal reflux disease and peptic ulcer disease. PPIs are considered safe and effective. It is
Vasudevan G. Naidoo
doaj +2 more sources
Multimorbidities and Overprescription of Proton Pump Inhibitors in Older Patients. [PDF]
To determine whether there is an association between overprescription of proton pump inhibitors (PPIs) and multimorbidities in older patients.Multicenter prospective study.Acute geriatric medicine at the University Hospital of Nantes and the Hospital of ...
Anne Delcher +5 more
doaj +1 more source
(1) Background: Hepatic encephalopathy (HE) is a common complication in cirrhosis patients, and recently, clinical evidence indicates that a higher risk of HE is associated with the usage of proton pump inhibitors.
Pan Zhang +6 more
doaj +1 more source
Overprescribing proton pump inhibitors [PDF]
Proton pump inhibitors are one of the most frequently prescribed classes of drug in the world because they combine a high level of efficacy with low toxicity. In 2006, expenditure on these drugs was £425m (€595m; $872m) in England1 and £7bn globally.2 Yet studies consistently show that proton pump inhibitors are being overprescribed worldwide in both ...
Ian, Forgacs, Aathavan, Loganayagam
openaire +2 more sources
Objectives Proton pump inhibitors, such as omeprazole and pantoprazole, are frequently prescribed for the treatment of acid reflux. However, those medications have been shown to affect a variety of physiologic processes, including bone homeostasis and ...
Bhavneet K. Chawla +3 more
doaj +1 more source
Use of Proton Pump Inhibitors in Hungary: Mixed-Method Study to Reveal Scale and Characteristics
BackgroundDue to their efficacy and tolerability, utilization of proton pump inhibitors (PPI) has significantly increased worldwide. Parallel to the clinical benefits, potential long-term side effects have been observed, which, along with increasing ...
Mária Matuz +7 more
doaj +1 more source
Chronic kidney disease (CKD) patients are exposed to more proton pump inhibitor (PPI)s compared to non-CKD patients. [PDF]
BACKGROUND:Proton pump inhibitor use is associated with incident chronic kidney disease, chronic kidney disease progression and end-stage renal disease.
Hee Jeong Lee +8 more
doaj +1 more source
Background Proton pump inhibitors are frequently used (and often overused) medications with adverse effects including vitamin B12 deficiency, Clostridium difficile colitis, and increased risk of chronic kidney disease.
Theodore W. Perry
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Clopidogrel and proton pump inhibitors [PDF]
In their comprehensive review of antithrombotic agents following acute coronary syndromes, Matteau and Bhatt[1][1] discuss the drug interaction between proton pump inhibitors and clopidogrel. They note that the COGENT trial, led by Bhatt, found no increased risk of major cardiovascular events at ...
openaire +5 more sources

