Results 1 to 10 of about 62,039 (256)

Deprescribing proton pump inhibitors

Singapore Medical Journal, 2023
Kim Jun Kevin Teh, Hai Kiat Troy Puar, Choon How How, Teck Kiang Malcolm Tan   +3 more
openaire   +4 more sources

Proton pump inhibitors

Reactions Weekly, 2015
Proton-pump inhibitors (PPIs) are a class of drugs that profoundly suppress gastric acid secretion, and thus have become the treatment of choice for gastro-oesophageal reflux disease and peptic ulcer disease. PPIs are considered safe and effective. It is
Vasudevan G. Naidoo
openaire   +3 more sources

Multimorbidities and Overprescription of Proton Pump Inhibitors in Older Patients. [PDF]

PLoS ONE, 2015
To determine whether there is an association between overprescription of proton pump inhibitors (PPIs) and multimorbidities in older patients.Multicenter prospective study.Acute geriatric medicine at the University Hospital of Nantes and the Hospital of ...
Anne Delcher, Sylvie Hily, Anne Sophie Boureau, Guillaume Chapelet, Gilles Berrut, Laure de Decker   +5 more
doaj   +1 more source

Overprescribing proton pump inhibitors [PDF]

BMJ, 2008
Proton pump inhibitors are one of the most frequently prescribed classes of drug in the world because they combine a high level of efficacy with low toxicity. In 2006, expenditure on these drugs was £425m (€595m; $872m) in England1 and £7bn globally.2 Yet studies consistently show that proton pump inhibitors are being overprescribed worldwide in both ...
Ian, Forgacs, Aathavan, Loganayagam
openaire   +2 more sources

Electroencephalography Signatures for Hepatic Encephalopathy in Cirrhosis Patients Treated with Proton Pump Inhibitors: An Exploratory Pilot Study

Biomedicines, 2022
(1) Background: Hepatic encephalopathy (HE) is a common complication in cirrhosis patients, and recently, clinical evidence indicates that a higher risk of HE is associated with the usage of proton pump inhibitors.
Pan Zhang, Lizhi Zhou, Li Chen, Zhen Zhang, Rui Han, Gangwen Guo, Haocheng Zhou   +6 more
doaj   +1 more source

The influence of proton pump inhibitors on tissue attachment around teeth and dental implants: A scoping review

Clinical and Experimental Dental Research, 2022
Objectives Proton pump inhibitors, such as omeprazole and pantoprazole, are frequently prescribed for the treatment of acid reflux. However, those medications have been shown to affect a variety of physiologic processes, including bone homeostasis and ...
Bhavneet K. Chawla, Robert E. Cohen, Elizabeth M. Stellrecht, Lisa M. Yerke   +3 more
doaj   +1 more source

Use of Proton Pump Inhibitors in Hungary: Mixed-Method Study to Reveal Scale and Characteristics

Frontiers in Pharmacology, 2020
BackgroundDue to their efficacy and tolerability, utilization of proton pump inhibitors (PPI) has significantly increased worldwide. Parallel to the clinical benefits, potential long-term side effects have been observed, which, along with increasing ...
Mária Matuz, Ria Benkő, Zsófia Engi, Krisztina Schváb, Péter Doró, Réka Viola, Mária Szabó, Gyöngyvér Soós   +7 more
doaj   +1 more source

Chronic kidney disease (CKD) patients are exposed to more proton pump inhibitor (PPI)s compared to non-CKD patients. [PDF]

PLoS ONE, 2018
BACKGROUND:Proton pump inhibitor use is associated with incident chronic kidney disease, chronic kidney disease progression and end-stage renal disease.
Hee Jeong Lee, Haekyung Lee, Song Hee Oh, Joonbyung Park, Suyeon Park, Jin Seok Jeon, HyunJin Noh, Dong Cheol Han, Soon Hyo Kwon   +8 more
doaj   +1 more source

Overuse of proton pump inhibitors [PDF]

Polish Archives of Internal Medicine, 2015
Proton pump inhibitors (PPIs) are currently the most effective drugs inhibiting hydrochloric acid secretion. They have replaced histamine type 2 receptor antagonists in the majority of clinical indications, for example, functional dyspepsia, gastroesophageal reflux disease, or drug‑induced upper gastrointestinal tract injury.
Dorota, Ksiądzyna, Adam, Szeląg, Leszek, Paradowski   +2 more
openaire   +2 more sources

Abrupt-onset, profound erectile dysfunction in a healthy young man after initiating over-the-counter omeprazole: a case report

Journal of Medical Case Reports, 2021
Background Proton pump inhibitors are frequently used (and often overused) medications with adverse effects including vitamin B12 deficiency, Clostridium difficile colitis, and increased risk of chronic kidney disease.
Theodore W. Perry
doaj   +1 more source