Results 11 to 20 of about 1,320,066 (287)

Chronic kidney disease (CKD) patients are exposed to more proton pump inhibitor (PPI)s compared to non-CKD patients. [PDF]

open access: yesPLoS ONE, 2018
BACKGROUND:Proton pump inhibitor use is associated with incident chronic kidney disease, chronic kidney disease progression and end-stage renal disease.
Hee Jeong Lee   +8 more
doaj   +1 more source

Abrupt-onset, profound erectile dysfunction in a healthy young man after initiating over-the-counter omeprazole: a case report

open access: yesJournal of Medical Case Reports, 2021
Background Proton pump inhibitors are frequently used (and often overused) medications with adverse effects including vitamin B12 deficiency, Clostridium difficile colitis, and increased risk of chronic kidney disease.
Theodore W. Perry
doaj   +1 more source

Proton-Pump Inhibitors and Fragility Fractures in Vulnerable Older Patients [PDF]

open access: yes, 2017
To the Editor: Proton Pump Inhibitors (PPIs) taken for ≥1 year have been linked to increased fragility fracture (FF) risk, prompting the US FDA to issue a related warning.
W Henley (16997595)   +7 more
core   +6 more sources

Overprescribing proton pump inhibitors [PDF]

open access: yesBMJ, 2008
Proton pump inhibitors are one of the most frequently prescribed classes of drug in the world because they combine a high level of efficacy with low toxicity. In 2006, expenditure on these drugs was £425m (€595m; $872m) in England1 and £7bn globally.2 Yet studies consistently show that proton pump inhibitors are being overprescribed worldwide in both ...
Ian, Forgacs, Aathavan, Loganayagam
openaire   +2 more sources

Proton-pump inhibitors and risk of renal disease [PDF]

open access: yesJournal of Nephropharmacology, 2017
Proton pump inhibitors (PPIs) are one group of drugs that inhibit gastric acid secretion by binding irreversibly to the gastric proton pump to the gastric proton pump.
Mahrang Hedaiaty   +3 more
doaj   +1 more source

Proton pump inhibitors and gastroenteritis [PDF]

open access: yesEuropean Journal of Epidemiology, 2016
An association between proton pump inhibitor (PPI) therapy and bacterial gastroenteritis has been suggested as well as contradicted. The aim of this study was to examine the association between the use of PPIs and occurrence of bacterial gastroenteritis in the prospective Rotterdam Study.
Hassing, Robert-Jan   +4 more
openaire   +2 more sources

Association between proton pump inhibitor therapy and clostridium difficile infection: a contemporary systematic review and meta-analysis. [PDF]

open access: yes, 2012
Introduction Emerging epidemiological evidence suggests that proton pump inhibitor (PPI) acid-suppression therapy is associated with an increased risk of Clostridium difficile infection (CDI).
Sutton, AJ   +77 more
core   +1 more source

Risk of Bacterial Infection from Proton Pump Inhibitor Use

open access: yesThe Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2017
Currently, proton pump inhibitors are used in a wide range of patients with gastroesophageal reflux disease, peptic ulcer, and upper gastrointestinal symptoms such as dyspepsia.
Sung Soo Kim   +7 more
doaj   +1 more source

Association of Histamine-2 Blockers and Proton-Pump Inhibitors With Delirium Development in Critically Ill Adults: A Retrospective Cohort Study

open access: yesCritical Care Explorations, 2021
OBJECTIVES:. Histamine-2 receptor antagonists are commonly administered for stress ulcer prophylaxis in critically ill adults and may be associated with delirium development.
Ami Shiddapur, BS   +3 more
doaj   +1 more source

Overuse of proton pump inhibitors [PDF]

open access: yesPolish Archives of Internal Medicine, 2015
Proton pump inhibitors (PPIs) are currently the most effective drugs inhibiting hydrochloric acid secretion. They have replaced histamine type 2 receptor antagonists in the majority of clinical indications, for example, functional dyspepsia, gastroesophageal reflux disease, or drug‑induced upper gastrointestinal tract injury.
Dorota, Ksiądzyna   +2 more
openaire   +2 more sources

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