Results 11 to 20 of about 62,039 (256)

Clopidogrel and proton pump inhibitors [PDF]

Canadian Medical Association Journal, 2014
In their comprehensive review of antithrombotic agents following acute coronary syndromes, Matteau and Bhatt[1][1] discuss the drug interaction between proton pump inhibitors and clopidogrel. They note that the COGENT trial, led by Bhatt, found no increased risk of major cardiovascular events at ...
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Proton pump inhibitors and gastroenteritis [PDF]

European Journal of Epidemiology, 2016
An association between proton pump inhibitor (PPI) therapy and bacterial gastroenteritis has been suggested as well as contradicted. The aim of this study was to examine the association between the use of PPIs and occurrence of bacterial gastroenteritis in the prospective Rotterdam Study.
Hassing, Robert-Jan, Verbon, Annelies, Visser, H, Hofman, Bert, Stricker, Bruno   +4 more
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Pharmacology of proton pump inhibitors [PDF]

Current Gastroenterology Reports, 2008
The gastric H,K-ATPase is the primary target for the treatment of acid-related diseases. Proton pump inhibitors (PPIs) are weak bases composed of two moieties, a substituted pyridine with a primary pK(a) of about 4.0, which allows selective accumulation in the secretory canaliculus of the parietal cell, and a benzimidazole with a second pK(a) of about ...
Jai Moo, Shin, George, Sachs
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Proton-pump inhibitors and risk of renal disease [PDF]

Journal of Nephropharmacology, 2017
Proton pump inhibitors (PPIs) are one group of drugs that inhibit gastric acid secretion by binding irreversibly to the gastric proton pump to the gastric proton pump.
Mahrang Hedaiaty, Mohammad Reza Tamadon, Armin Amiri, Leila Mahmoodnia   +3 more
doaj   +1 more source

Risk of Bacterial Infection from Proton Pump Inhibitor Use

The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2017
Currently, proton pump inhibitors are used in a wide range of patients with gastroesophageal reflux disease, peptic ulcer, and upper gastrointestinal symptoms such as dyspepsia.
Sung Soo Kim, Yunju Jo, Seun Ja Park, Jeong Seop Moon, Dong Ho Lee, Jae Jun Kim, Yong Chan Lee, Ethics and Education Committee of Korean College of Helicobacter and Upper Gastrointestinal Research   +7 more
doaj   +1 more source

Association of Histamine-2 Blockers and Proton-Pump Inhibitors With Delirium Development in Critically Ill Adults: A Retrospective Cohort Study

Critical Care Explorations, 2021
OBJECTIVES:. Histamine-2 receptor antagonists are commonly administered for stress ulcer prophylaxis in critically ill adults and may be associated with delirium development.
Ami Shiddapur, BS, Christine E. Kistler, MD, MASc, Jan Busby-Whitehead, MD, C. Adrian Austin, MD, MSCR   +3 more
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Hypomagnesemia Induced by Long-Term Treatment with Proton-Pump Inhibitors

Gastroenterology Research and Practice, 2015
In 2006, hypomagnesemia was first described as a complication of proton-pump inhibitors. To address this issue, we systematically reviewed the literature.
Simone Janett, Pietro Camozzi, Gabriëlla G. A. M. Peeters, Sebastiano A. G. Lava, Giacomo D. Simonetti, Barbara Goeggel Simonetti, Mario G. Bianchetti, Gregorio P. Milani   +7 more
doaj   +1 more source

ENDOSCOPIC AND HISTOPATHOLOGIC GASTRIC CHANGES IN CHRONIC USERS OF PROTON-PUMP INHIBITORS

Arquivos de Gastroenterologia, 2015
Background Proton-pump inhibitors have been used for at least two decades. They are among the most commonly sold drugs in the world. However, some controversy remains about the indications for their use and the consequences of their prolonged use ...
Sílvia Maria Perrone CAMILO, Élia Cláudia de Souza ALMEIDA, Benito André Silveira MIRANZI, Juliano Carvalho SILVA, Rosemary Simões NOMELINI, Renata Margarida ETCHEBEHERE   +5 more
doaj   +1 more source

Proton Pump Inhibitors and CKD [PDF]

Journal of the American Society of Nephrology, 2016
Proton pump inhibitors (PPIs) are taken by millions of people around the world, often for many months or even years, and some take PPIs on a permanent basis. PPIs, which are available both by prescription and over the counter, generally have an excellent overall safety profile.
Dennis G, Moledina, Mark A, Perazella
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Proton Pump Inhibitors and Gastritis

Journal of Clinical Biochemistry and Nutrition, 2008
Proton pump inhibitors (PPIs) are novel compounds that strongly inhibit the H(+)/K(+)-ATPase in the gastric parietal cells to cause profound suppression of acid secretion. Acid-generating ATPase, also known as vacuolar-type ATPase, is located in the lysozomes of leukocytes and osteoclasts and its activity is also reportedly influenced by treatment with
Suzuki, Masayuki, Suzuki, Hidekazu, Hibi, Toshifumi   +2 more
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