Results 41 to 50 of about 1,320,066 (287)

Proton Pump Inhibitors: Are They a Real Threat to the Patient?

open access: yesGE: Portuguese Journal of Gastroenterology, 2018
Background: Proton pump inhibitors are among the most frequently prescribed drugs in the world and are generally considered safe. However, there is growing concern regarding their safety.
Sofia Xavier   +2 more
doaj   +1 more source

Population-based cohort study: proton pump inhibitor use during pregnancy in Sweden and the risk of maternal and neonatal adverse events

open access: yesBMC Medicine, 2022
Background Approximately half of all women suffer from heartburn at some stage during pregnancy. The most effective treatment is proton pump inhibitors, but the safety of use during pregnancy cannot be guaranteed. This study aimed to elucidate the effect
Esmee M. Breddels   +6 more
doaj   +1 more source

Proton Pump Inhibitors in Kidney Disease [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2018
Proton pump inhibitors (PPIs) are one of the most frequently used classes of medications in the world, and they are particularly common among patients receiving hemodialysis. In 2015, nearly one half of all Medicare-enrolled patients on hemodialysis received a prescription for an acid suppressant ([
Lazarus, Benjamin, Grams, Morgan E.
openaire   +4 more sources

Combined therapy with proton pump inhibitors and clopidogrel – focus on cardiovascular risk

open access: yes, 2019
Aim. To analyze accessible studies on the problem of potential interaction of proton pump inhibitors and clopidogrel and to evaluate the influence of combined therapy with these pharmacologic agents on cardiovascular adverse effects development ...
Evgenii V. Kravchenko   +4 more
core   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

ANTISECRETORY TREATMENT FOR PEDIATRIC GASTROESOPHAGEAL REFLUX DISEASE - A SYSTEMATIC REVIEW

open access: yesArquivos de Gastroenterologia, 2017
BACKGROUND: Proton pump inhibitors and histamine H2 receptor antagonists are two of the most commonly prescribed drug classes for pediatric gastroesophageal reflux disease, but their efficacy is controversial.
Ângelo Zambam de MATTOS   +4 more
doaj   +1 more source

Proton-pump inhibitors used in the out-patient clinic.

open access: yes, 2018
Proton-pump inhibitors used in the out-patient clinic.
Joonbyung Park (5746610)   +8 more
core   +1 more source

Characteristics and Outcomes of Male Participants in a Multicenter Longitudinal Australian Study Cohort

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to determine the differences in demographic, serologic, and clinical characteristics between male and female patients with systemic sclerosis (SSc) in an Australian cohort. Methods This was a retrospective observational study using data from the Australian Scleroderma Cohort Study.
Emily Lin   +14 more
wiley   +1 more source

Proton pump inhibitors overuse: only inappropriate prescriptions or further iatrogenic damage?

open access: yesItalian Journal of Medicine, 2015
Proton pump inhibitors (PPIs) are the most potent drugs for reducing gastric acid secretion; so, since their release in the late 1980s, they have been recommended as the first therapeutic choice for many gastroesophageal diseases, risk reduction in or ...
Mario Visconti
doaj   +1 more source

Superlubricity and Corrosion Inhibition Properties of Solvate Ionic Liquids in Hybrid Carbon Fiber Reinforced Plastic–Steel Interfaces

open access: yesAdvanced Engineering Materials, EarlyView.
Solvate ionic liquids lubrication reduced the coefficient of friction by ∼60% compared to dry sliding, reaching steady‐state values as low as 0.04–0.05. Corrosion weight‐loss measurements in 1 M HCl further demonstrated significant inhibition behavior, with only 100 ppm of [Li(G3)][TFSI] (∼68.5 μL/L) reducing corrosion‐product weight loss by 63 ...
Sameh Dabees   +6 more
wiley   +1 more source

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