Results 51 to 60 of about 1,399,448 (251)

Do we need gastric acid? [PDF]

, 2008
Evidence from comparative anatomy and physiology studies indicates that gastric acid secretion developed during the evolution of vertebrates approximately 350 million years ago.
Lippl, F., Lippl, F, Schiefke, I, Prinz, C., Pohl, D, Rogler, G., Prinz, C, Fox, M, Mönnikes, H, Schiefke, I., Keller, J, Seidler, U, Allescher, H D, Dauer, M, Göke, B., Seidler, U., Keller, J., Fox, M., Göke, B, Pohl, D., Moennikes, H., Dauer, M., Rogler, G, Kandahar Study Group, Fried, M, Allescher, H. D., Pohl, D.;Fox, M.;Fried, M.;Göke, B.;Prinz, C.;Mönnikes, H.;Rogler, G.;Dauer, M.;Keller, J.;Lippl, F.;Schiefke, I.;Seidler, U.;Allescher, H. D., Pohl, D;Fox, M;Fried, M;Göke, B;Prinz, C;Monnikes, H;Rögler, G;Dauer, M;Keller, J;Lippl, F;Schiefke, I;Seidler, U;Allescher, HD, Prinz C, Allescher HD, Mönnikes H, Schiefke I, Rogler G, Fox M, Pohl D, Seidler U, Dauer M, Keller J, Göke B, Lippl F, Fried M   +40 more
core   +1 more source

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source

Association between proton pump inhibitor use and risk of fracture: A population-based case-control study.

PLoS ONE, 2020
ObjectivesThe purpose of this study was to reconfirm the association between the risk of fracture and proton pump inhibitor use and to establish evidence for defining a high-risk group of patients among proton pump inhibitor users.MethodsA nested case ...
Jong Joo Kim, Eun Jin Jang, Jiwon Park, Hyun Soon Sohn   +3 more
doaj   +1 more source

Comparison of Proton Pump Inhibitor and Triple Therapy Regimen for Laryngospharyngeal Reflux Disease

Journal of Nepal Health Research Council, 2020
Background: Laryngopharyngeal reflux is retrograde flow of contents of the stomach to the larynx and the pharynx. The study aims to compare two regimens (proton pump inhibitor monotherapy versus triple therapy) on the outcome of Helicobactor pylori ...
Apar Pokharel, Jaya Prakash Mayya, Hari Prasad Upadhyay   +2 more
doaj   +1 more source

Do proton pump inhibitors affect the biomechanical efficiency of implant?- a systematic review

Journal of Oral Biology and Craniofacial Research, 2022
-: Purpose: This systematic review was executed to determine the influence of proton pump inhibitors on biomechanical efficiency of dental implants. Materials and methods: The comprehensive online literature search was conducted on digital database of ...
Varsha Verma
doaj   +1 more source

Selenium‐Integrated Cyanine Dye With Enhanced Photophysical Properties for Optoacoustic‐Guided Cancer Imaging and Therapy

Advanced Functional Materials, EarlyView.
This study introduces selenium‐integrated cyanine dye (Se‐Cyn), with superior photostability, absorption, and photothermal efficiency, outperforming ICG in NIR window. Its nanoparticle form remains stable in water, accumulates in tumors, and enables strong optoacoustic imaging and effective phototherapy outcomes.
Divyesh Shelar, Snehal Salunkhe, Tony Fröhlich, Uwe Klemm, Pia Anzenhofer, Birgit Rathkolb, Martin Hrabě de Angelis, Oliver Plettenburg, Michael Sattler, Sudesh T. Manjare, Vipul Gujrati, Vasilis Ntziachristos   +11 more
wiley   +1 more source

Proton Pump Inhibitors Associated With Drug-Induced Lupus Erythematosus

, 2022
International audienceThis descriptive case series investigates the potential association between the use of proton pump inhibitors and drug-induced lupus erythematosus in cases reported in 2 large pharmacovigilance ...
Tubach, Florence, Bataille, Pauline, Barbaud, Annick, Aroux-Pavard, Marine, Lebrun-Vignes, Bénédicte, Philibert, Christelle, Chasset, François   +6 more
core   +1 more source

Protein‐Polymer Dynamic Hydrogels Utilizing Native Ligand Binding for Injectable Therapeutic Delivery and 3D Printing

Advanced Healthcare Materials, EarlyView.
Dynamic nanocolloidal hydrogels were synthesized via the co‐assembly of ligand‐modified spheroidal hyperbranched poly(glycerol) (HPG) and soluble albumin nanoparticles (SANs). Co‐assembly occurred through self‐association of the HPG, as well as its interaction with SANs via native ligand binding.
S. Cem Millik, Yonghui Wang, Kefan Song, Jessica M. Snyder, LeAnn Le, Lauren G. Brown, Shanny Hsuan Kuo, Ashleigh B. Theberge, Suzie H. Pun, Alshakim Nelson   +9 more
wiley   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Proton pump inhibitors are still overprescribed for hospitalized children

, 2022
OBJECTIVE: The use of proton pump inhibitors has increased exponentially over the past 20 years. Several side effects have been reported and concerns exist about the consequences of long-term proton pump inhibitors on health, leading to limitation of ...
BAILHACHE, Marion, TETARD, Candice, ARNOUX, A., LAMIREAU, Thierry, REBOUISSOUX, Laurent, CLOUZEAU, Haude, ENAUD, Raphael, T. Lamireau, C. Tetard, A. Arnoux, M. Bailhache, L. Rebouissoux, R. Enaud, H. Clouzeau   +13 more
core   +1 more source