ANTI-ULCER AGENTS: A PHARMACOLOGICAL UPDATE OF THE PAST TEN YEARS
New anti-ulcer substances are still vitally necessary for the people of countries such as India and South Africa to avoid high cost of the most prescribed marketed anti-ulcer drugs (proton-pump inhibitors).
S. Mandal, Subhojit Dawn, A. Bose
semanticscholar +3 more sources
Scope of medicinal flora as effective anti ulcer agents
Gastric ulcer generally results from persistent erosions and damage of the stomach wall which become perforated and develops into peritonitis and massive haemorrhage as a result of inhibition of the synthesis of mucus, bicarbonate and prostaglandins. The
S. hya +4 more
semanticscholar +3 more sources
A series of alkylazulene-1-sodium sulfonate derivatives which has an isopropyl group at 6-position were synthesized, and their anti-ulcer activities were examined in Shay pylorus-ligated rats. The values of lipophilicity (log P) as a parameter of these new azulene derivatives were also examined in reference to the structure-activity relationship.
T. Yanagisawa +4 more
semanticscholar +4 more sources
Effects of anti-ulcer agents on thermal-cortisone-induced ulcers in rats.
N. Inatomi, Y. Ishihara, S. Okabe
semanticscholar +4 more sources
Use of gastroprotective agents in recommended doses in hospitalized patients receiving NSAIDs: a drug utilization study [PDF]
OBJECTIVE: In recent years, studies investigated to what extend recommendations for co-prescribing gastroprotective agents in prevention of NSAID-induced gastrointestinal complications are followed in clinical practice.
Bilušić, Marinko +6 more
core +1 more source
Topical agents or dressings for pain in venous leg ulcers. [PDF]
Venous leg ulcers affect up to 1% of people at some time in their lives and are often painful. The main treatments are compression bandages and dressings.
Briggs, M +2 more
core +3 more sources
Comparison of omeprazole, metronidazole and clarithromycin with omeprazole/amoxicillin dual-therapy for the cure of Helicobacter pylori infection [PDF]
In this randomized, multicenter trial, we evaluated the effectiveness and side effect profile of a modified omeprazole-based triple therapy to cure Helicobacter pylori infection.
Bayerdörffer, Ekkehard +11 more
core +1 more source
Precise role of H pylori in duodenal ulceration [PDF]
The facts that H pylori infection is commoner in duodenal ulcer (DU) patients than in the normal population, and that eradication results in most cases being cured, have led to the belief that it causes DU. However, early cases of DU are less likely than
Hobsley, M, Holton, J, Tovey, FI
core +1 more source
Use of recombinant virus replicon particles for vaccination against Mycobacterium ulcerans disease [PDF]
Buruli ulcer, caused by infection with Mycobacterium ulcerans, is a necrotizing disease of the skin and subcutaneous tissue, which is most prevalent in rural regions of West African countries.
Bolz, Miriam +3 more
core +3 more sources
IN SILICO PHARMACOKINETIC, BIOACTIVITY AND TOXICITY EVALUATION OF SOME SELECTED ANTI-ULCER AGENTS
Peptic ulcer is a major health burden that recognized as a group of upper gastro-intestinal tract disorders. The aim of the therapy is to provide relieve from pain and prevent ulcer complications.
Neeraj Kumar +4 more
semanticscholar +1 more source

