Synthesis, characterization, anti-ulcer action and molecular docking evaluation of novel benzimidazole-pyrazole hybrids [PDF]
A series of six novel benzimidazole-pyrazole hybrid molecules was synthesized and characterized using elemental analysis (CHN) and spectroscopic methods (1HNMR, FT-IR).
Abida Noor +6 more
doaj +2 more sources
ANTI-ULCER ACTIVITY OF LEGUMINOSAE PLANTS [PDF]
Context Ulcer is the most common gastrointestinal disturbance resulting from an inadequate gastric mucosal defense. Several drugs are available in the market to address the disease; however, these drugs are associated with unnecessary side effects ...
Noemi D. PAGUIGAN +2 more
doaj +2 more sources
Plants with Anti-Ulcer Activity and Mechanism: A Review of Preclinical and Clinical Studies [PDF]
Deshanda Kurniawan Prayoga,1,* Diah Lia Aulifa,2,* Arif Budiman,3,* Jutti Levita4,* 1Master Program in Pharmacy, Faculty of Pharmacy, Padjadjaran University, Sumedang, West Java, 45363, Indonesia; 2Department of Pharmaceutical Analysis ...
Prayoga DK +3 more
doaj +1 more source
In Vivo and in Vitro Investigations of the Effects of Iranian Honeybee (Hymenoptera: Apis mellifera) Venom and Propolis on Leishmania Major [PDF]
Background: Leishmaniasis, as a neglected health issue, is spreading in most parts of the world. It is one of the most important vector-borne diseases in Iran. Bee venom has shown a wide range of medicinal properties.
Qasem Asgari +5 more
doaj +1 more source
Exendin-4, a glucagon-like peptide-1 analogue accelerates healing of chronic gastric ulcer in diabetic rats. [PDF]
Diabetes mellitus is an independent risk factor for impaired healing of peptic ulcers, and there are currently no supplementary therapeutics other than the standard antipeptic medicine to improve the ulcer healing in diabetes.
Yen-Cheng Chen +5 more
doaj +1 more source
Association between eupatilin and reduction in small bowel bleeding in aspirin users and aspirin plus acid suppressant users [PDF]
Background/Aims Capsule endoscopy (CE) has shown that low-dose aspirin occasionally causes small bowel (SB) bleeding. We herein evaluated the protective effects of mucoprotective agents (MPAs) on SB bleeding in aspirin users using the nationwide database
Hyun Seok Lee +4 more
doaj +1 more source
Combined Inflammatory and Metabolic Defects Reflected by Reduced Serum Protein Levels in Patients with Buruli Ulcer Disease [PDF]
Buruli ulcer is a skin disease caused by Mycobacterium ulcerans that is spreading in tropical countries, with major public health and economic implications in West Africa.
Reid Oldenburg (550232) +63 more
core +2 more sources
Illness meanings and experiences for pre-ulcer and ulcer conditions of Buruli ulcer in the Ga-West and Ga-South municipalities of Ghana [PDF]
: BACKGROUND: Ghana is a Buruli ulcer (BU) endemic country yet there is paucity of socio-cultural research on BU. Examining distinctive experiences and meanings for pre-ulcers and ulcers of BU may clarify the disease burden, illness experience and local ...
Kwakye-Maclean Cynthia +14 more
core +1 more source
Imprudent Gastro-protective Approach in Majority of Specialists’ Clinics of a Tertiary Hospital [PDF]
Introduction: One out of four prescriptions in out-patient departments contains a gastro-protective drug (APUD) - PPI/ H2 Blockers/ Antacids/ Ulcer Protective’s. These drugs should be prescribed only when there is a justified indication. To assess the
Hardik Rameshbhai Patel, Priti Dhande
doaj +1 more source
Mycolactone Diffuses into the Peripheral Blood of Buruli Ulcer Patients - Implications for Diagnosis and Disease Monitoring. [PDF]
BACKGROUND: Mycobacterium ulcerans, the causative agent of Buruli ulcer (BU), is unique among human pathogens in its capacity to produce a polyketide-derived macrolide called mycolactone, making this molecule an attractive candidate target for diagnosis ...
Le Chevalier, Fabien +53 more
core +1 more source

