Results 11 to 20 of about 367 (215)

Refractory Peptic Ulcer Disease [PDF]

open access: yesThe Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2019
The eradication of Helicobacter pylori and the widespread use of effective antisecretory therapies, including proton pump inhibitors, have improved the management of peptic ulcer disease. However, in some patients, peptic ulcer disease is refractory to 8
Hyun Lim
doaj   +1 more source

Association between eupatilin and reduction in small bowel bleeding in aspirin users and aspirin plus acid suppressant users [PDF]

open access: yesThe Korean Journal of Internal Medicine, 2023
Background/Aims Capsule endoscopy (CE) has shown that low-dose aspirin occasionally causes small bowel (SB) bleeding. We herein evaluated the protective effects of mucoprotective agents (MPAs) on SB bleeding in aspirin users using the nationwide database
Hyun Seok Lee   +4 more
doaj   +1 more source

Exendin-4, a glucagon-like peptide-1 analogue accelerates healing of chronic gastric ulcer in diabetic rats. [PDF]

open access: yesPLoS ONE, 2017
Diabetes mellitus is an independent risk factor for impaired healing of peptic ulcers, and there are currently no supplementary therapeutics other than the standard antipeptic medicine to improve the ulcer healing in diabetes.
Yen-Cheng Chen   +5 more
doaj   +1 more source

Imprudent Gastro-protective Approach in Majority of Specialists’ Clinics of a Tertiary Hospital [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Introduction: One out of four prescriptions in out-patient departments contains a gastro-protective drug (APUD) - PPI/ H2 Blockers/ Antacids/ Ulcer Protective’s. These drugs should be prescribed only when there is a justified indication. To assess the
Hardik Rameshbhai Patel, Priti Dhande
doaj   +1 more source

Synthesis, characterization, anti-ulcer action and molecular docking evaluation of novel benzimidazole-pyrazole hybrids

open access: yesChemistry Central Journal, 2017
A series of six novel benzimidazole-pyrazole hybrid molecules was synthesized and characterized using elemental analysis (CHN) and spectroscopic methods (1HNMR, FT-IR).
Abida Noor   +6 more
doaj   +1 more source

Prevention of Peptic Ulcer Associated with Aspirin and Antiplatelet Agent

open access: yesThe Korean Journal of Gastroenterology, 2020
The Korean guidelines for the Clinical Guidelines for Drug-related Peptic Ulcer were revised under the Korean College of Helicobacter and Upper Gastrointestinal Research in 2020.
Ji Yong Ahn
doaj   +1 more source

Risk of Peptic Ulcer Bleeding Associated with Infection, Nonsteroidal Anti-inflammatory Drugs, and Low-dose Aspirin Therapy in Peptic Ulcer Disease: A Case-control Study [PDF]

open access: yesThe Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2019
Background/Aims The association between Helicobacter pylori infection and nonsteroidal anti-inflammatory drugs (NSAIDs) or low-dose aspirin therapy as a risk factor for peptic ulcer bleeding (PUB) remains unclear.
Seung In Seo   +6 more
doaj   +1 more source

Pharmacokinetic and pharmacological studies on cetraxate, an anti-ulcer agent.

open access: yesFolia Pharmacologica Japonica, 1985
Cetraxate hydrochloride was administered either orally or intravenously to rabbits, and its concentration in body fluids was determined by using the HPLC method. Cetraxate was easily hydrolyzed in the gastrointestinal tract and blood, and it was metabolized to p-hydroxyphenylpropionic acid (PHPA) and a new metabolite, p-hydroxybenzoic acid (PHBA ...
TANAKA, Hisashi, NAITO, Shun-ichi
openaire   +3 more sources

Ultrasound-Assisted Ugi-Azide Multicomponent Reaction for the Synthesis of 1,5-Disubstituted Tetrazoles

open access: yesChemistry Proceedings, 2023
The Ugi-azide MCR (UA) is one of the most efficient methods for the synthesis of 1,5-disubstituted-1H-tetrazoles (1,5-DS-T). Complex drug-like scaffolds incorporating tetrazoles have demonstrated a wide range of therapeutic benefits such as anti ...
Alejandro Corona-Díaz   +4 more
doaj   +1 more source

Flavonoids: A Potent Substance in Anti-ulcer and Hepatoprotective Agents

open access: yesJournal of Natural Remedies, 2022
Herbs have been used to treat various diseases in one form or another for the betterment of mankind since the ancient ages. As a result of this usage, the situation gradually deteriorated due to overexploitation, resulting in a decrease in natural resource production.
G. S. Chakraborthy   +4 more
openaire   +1 more source

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