Results 31 to 40 of about 91,275 (259)

Prospects for the development of a subunit vaccine against Mycobacterium ulcerans disease (Buruli ulcer) [PDF]

, 2014
Buruli ulcer (BU) is a slow progressing disease of the skin and subcutaneous tissue caused by Mycobacterium ulcerans. It presents in different clinical forms ranging from small non-ulcerative nodules to large ulcers and sometimes multiple ulcerations ...
Bolz, Miriam
core   +1 more source

Design, Synthesis and Biological Evaluation of a Novel Series of Thiadiazole-Based Anticancer Agents as Potent Angiogenesis Inhibitors [PDF]

, 2021
Background: Thiadiazole has attracted a great deal of interest as a versatile heterocycle for the discovery and development of potent anticancer agents. Thiadiazole derivatives exert potent antitumor activity against a variety of human cancer cell lines ...
Turan, Gulhan, Gülhan Turan, KAPLANCIKLI, ZAFER ASIM, ALTUĞ, BURCUGÜL, Ali S. Koparal, KOPARAL, ALİ SAVAŞ, Ayşe T. Koparal, Burcugül Altuğ-Tasa, Betül Kaya-Çavuşoğlu, Zafer A. Kaplancıklı, Kaya-cavusoglu, Betul   +10 more
core   +1 more source

Experimental infection of the pig with Mycobacterium ulcerans: a novel model for studying the pathogenesis of Buruli ulcer disease. [PDF]

, 2014
BACKGROUND Buruli ulcer (BU) is a slowly progressing, necrotising disease of the skin caused by infection with Mycobacterium ulcerans. Non-ulcerative manifestations are nodules, plaques and oedema, which may progress to ulceration of large parts of ...
Miriam Bolz, Bolz, Miriam, Gerd Pluschke, Gert Zimmer, Meret E Ricklin, Marie-Thérèse Ruf, Ruf, Marie-Thérèse, Ricklin, Meret E, Ruggli, Nicolas, Zimmer, Gert, Ricklin, Meret E., Nicolas Ruggli, Pluschke, Gerd   +12 more
core   +1 more source

Pharmacokinetic and pharmacological studies on cetraxate, an anti-ulcer agent.

Folia Pharmacologica Japonica, 1985
Cetraxate hydrochloride was administered either orally or intravenously to rabbits, and its concentration in body fluids was determined by using the HPLC method. Cetraxate was easily hydrolyzed in the gastrointestinal tract and blood, and it was metabolized to p-hydroxyphenylpropionic acid (PHPA) and a new metabolite, p-hydroxybenzoic acid (PHBA ...
TANAKA, Hisashi, NAITO, Shun-ichi
openaire   +3 more sources

Clinical characteristics and poor predictors of anti-NXP2 antibody-associated Chinese JDM children

Pediatric Rheumatology Online Journal, 2021
Background Juvenile dermatomyositis (JDM) is a rare and sometimes fatal disease in children. The anti-NXP2 antibody is one of the most common antibodies and muscle ischaemia associated with NXP2 autoantibodies was a severe subtype of JDM.
Xinning Wang, Yuchuan Ding, Zhixuan Zhou, Jun Hou, Yingjie Xu, Jianguo Li   +5 more
doaj   +1 more source

Clinical Guidelines for Drug-Related Peptic Ulcer, 2020 Revised Edition

Gut and Liver, 2020
Korean guidelines for nonsteroidal anti-inflammatory drug (NSAID)-induced peptic ulcer were previously developed in 2009 with the collaboration of the Korean College of Helicobacter and Upper Gastrointestinal Research and Korean Society of ...
Moon Kyung Joo, Chan Hyuk Park, Joon Sung Kim, Jae Myung Park, Ji Yong Ahn, Bong Eun Lee, Jeong Hoon Lee, Hyo-Joon Yang, Yu Kyung Cho, Chang Seok Bang, Beom Jin Kim, Hye-Kyung Jung, Byung-Wook Kim, Yong Chan Lee, Korean College of Helicobacter Upper Gastrointestinal Research   +14 more
doaj   +1 more source

Mycolactone-dependent depletion of endothelial cell thrombomodulin is strongly associated with fibrin deposition in Buruli ulcer lesions [PDF]

, 2015
A well-known histopathological feature of diseased skin in Buruli ulcer (BU) is coagulative necrosis caused by the Mycobacterium ulcerans macrolide exotoxin mycolactone.
Simmonds, RE, Esmon Charles T., Gerd Pluschke, Alexander Stainer, Alexander Stainer (771266), Josefin Ahnström (771267), Vogel Moritz, Stainer Alexander, Wu, HL, Hua-Lin Wu (70210), Ruf, Marie-Thérèse, Pluschke, G, Belinda S. Hall, Vogel, Moritz, Ahnström Josefin, Simmonds Rachel E., Vogel, M, Hall Belinda S., Marie-Thérèse Ruf (2280196), Simmonds, Rachel E., Ogbechi Joy, Moritz Vogel, Moritz Vogel (267190), Hall, Belinda S., Stainer, Alexander, Behr, Marcel A., Katherine Bodman-Smith, Josefin Ahnström, Bodman-Smith, K, Esmon, Charles T., Ogbechi, J, Ahnström, J, Rachel E Simmonds, Charles T. Esmon, Pluschke, Gerd, Charles T Esmon, Wu, Hua-Lin, Joy Ogbechi (546561), Hua-Lin Wu, Charles T. Esmon (280612), Joy Ogbechi, Bodman-Smith Katherine, Marie-Thérèse Ruf, Esmon, CT, Katherine Bodman-Smith (771265), Belinda S. Hall (546558), Rachel E. Simmonds, Wu Hua-Lin, Ruf Marie-Thérèse, Pluschke Gerd, Ruf, MT, Ahnström, Josefin, Gerd Pluschke (7855), Ogbechi, Joy, Stainer, A, Belinda S Hall, Rachel E. Simmonds (546562), Bodman-Smith, Katherine, Hall, BS   +58 more
core   +1 more source

Monitoring of human cellular immune responses in infectious diseases : malaria vaccine associated responses and immune characterization of Buruli ulcer patients [PDF]

, 2006
Within the context of the establishment of a virosomal-based subunit malaria vaccine including synthetic peptides derived from Plasmodium falciparum antigens demonstrated that it is possible to improve immunogenic properties of synthetic peptides in a ...
Peduzzi, Elisabetta Martina
core   +1 more source

Investigation of antiulcer activity of the thick extract of immature walnut fruits on the model of diclofenac-reduced gastric ulcer of rats

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
Topicality. It is known from the literature that the walnut composition includes tannins, derivatives of ellagic acid, catechins, derivatives of dicarboxylated acids, nucleic acids, amino acids that independently of one another have antioxidant ...
Ye. V. Zalygina , О. A. Podpletnya
doaj   +1 more source

Flavonoids: A Potent Substance in Anti-ulcer and Hepatoprotective Agents

Journal of Natural Remedies, 2022
Herbs have been used to treat various diseases in one form or another for the betterment of mankind since the ancient ages. As a result of this usage, the situation gradually deteriorated due to overexploitation, resulting in a decrease in natural resource production.
G. S. Chakraborthy, null Pinkal Patel, Sachin Sharma, Rupal K. Jani, Snigdha Das Mandal   +4 more
openaire   +1 more source