Results 51 to 60 of about 148,724 (304)

Investigation of antiulcer activity of the thick extract of immature walnut fruits on the model of diclofenac-reduced gastric ulcer of rats

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
Topicality. It is known from the literature that the walnut composition includes tannins, derivatives of ellagic acid, catechins, derivatives of dicarboxylated acids, nucleic acids, amino acids that independently of one another have antioxidant ...
Ye. V. Zalygina , О. A. Podpletnya
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Cytoprotective Effect of SU-88, an Anti-Ulcer Agent, in the Rat

open access: yesJapanese Journal of Pharmacology, 1984
The gastric cytoprotective action of SU-88, an anti-ulcer agent, was studied in rats. SU-88 dose-dependently prevented the formation of gastric lesions induced by absolute ethanol as observed by PGE2. The efficacy of SU-88 when given i.p. was more potent than the p.o. administration.
SUWA, Toshio   +4 more
openaire   +3 more sources

In silico Pharmacokinetic, Bioactivity and Toxicity Evaluation of Some Selected Anti-Ulcer Agents

open access: yes, 2017
Peptic ulcer is a major health burden that recognized as a group of upper gastro-intestinal tract disorders. The aim of the therapy is to provide relieve from pain and prevent ulcer complications.
Shashank Shekhar Mishra   +4 more
core   +1 more source

Immunohistochemical monitoring of wound healing in antibiotic treated buruli ulcer patients [PDF]

open access: yes, 2014
While traditionally surgery has dominated the clinical management of Buruli ulcer (BU), the introduction of the combination chemotherapy with oral rifampicin and intramuscular streptomycin greatly improved treatment and reduced recurrence rates.
Arianna Andreoli   +9 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Comparing the ventilator-associated pneumonia incidence when pantoprazole or ranitidine is used for stress ulcer prophylaxis in critically ill adult patients

open access: yesInternational Archives of Health Sciences, 2019
Aim: Prophylaxis against stress ulcer in mechanically ventilated patients is one of the causes for ventilator-associated pneumonia (VAP). Our aim was evaluating the effect of intravenous pantoprazole and ranitidine in the incidence of VAP in critically ...
Reza Nikandish   +8 more
doaj   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro   +6 more
wiley   +1 more source

Reduced risk of gastrointestinal bleeding associated with eupatilin in aspirin plus acid suppressant users: nationwide population-based study [PDF]

open access: yesThe Korean Journal of Internal Medicine
Background/Aims Mucoprotective agents, such as eupatilin, are often prescribed to prevent gastrointestinal (GI) bleeding in addition to an acid suppressant despite the absence of a large-scale study. We evaluated the additional effect of eupatilin on the
Hyun Seok Lee   +4 more
doaj   +1 more source

Microscopic Identification of Etiological Agents of Mycotic Keratitis in Corneal Ulcer Patients at Tertiary Care Eye Hospital, Pondicherry

open access: yes, 2020
Fungal keratitis is one of the causes of severe ocular morbidity and blindness. The prevalence of fungal keratitis has been increased from 7–63%. Culture is mandatory for an Ophthalmologist to guide treatment.
Selvaraj Stephen   +3 more
core   +1 more source

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