Results 61 to 70 of about 91,275 (259)

Safety of Prescription Nonsteroidal Anti‐inflammatory Drugs in Adults With Inflammatory Bowel Disease: Data From a Large Administrative Claims Cohort

Arthritis Care &Research, EarlyView.
Objective The concern that nonsteroidal anti‐inflammatory drugs (NSAIDs) may precipitate flares of inflammatory bowel disease (IBD) has limited their use in managing musculoskeletal symptoms in those with IBD, but safety data are mixed. Methods This retrospective cohort study included patients with IBD aged at least 18 years from Optum's deidentified ...
Adam S. Mayer, Rui Xiao, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +4 more
wiley   +1 more source

Interferon-γ is a crucial activator of early host immune defense against Mycobacterium ulcerans infection in mice [PDF]

, 2016
Buruli ulcer (BU), caused by infection with Mycobacterium ulcerans, is a chronic necrotizing human skin disease associated with the production of the cytotoxic macrolide exotoxin mycolactone.
Miriam Bolz, Bolz, Miriam, Gerd Pluschke, Miriam Bolz (309717), Raphael Bieri (849790), Raphael Bieri, Bieri, Raphael, Marie-Thérèse Ruf, Marie-Thérèse Ruf (2280196), Gerd Pluschke (7855), Ruf, Marie-Thérèse, Pluschke, Gerd   +11 more
core   +1 more source

Synthesis and anti-inflammatory, analgesic, and anti-ulcerogenic bioevaluation of new indole bioconjugates

Future Journal of Pharmaceutical Sciences
Background A new series of N-(3-(1H-indol-5-yl) phenyl) (5a–5j) derivatives and (4-(1H-indol-5-yl)piperazin-1-yl)(phenyl)methanone (9a–9j) derivatives was designed and synthesized to explore their potential anti-inflammatory, analgesic, and ulcerogenic ...
Savita Belwal, Venkata Krishna Reddy, Ram Bhavani, Vasudha Bakshi   +3 more
doaj   +1 more source

Discordance Between Systemic Lupus Erythematosus Disease Activity Index Domain Weights and Their Association With Organ Damage Accrual

Arthritis Care &Research, EarlyView.
Objective Studies of damage accrual in patients with systemic lupus erythematosus (SLE) show associations with disease activity measured by the SLE Disease Activity Index 2000 (SLEDAI‐2K), but these associations are imperfect. SLEDAI scores are powerfully influenced by weightings (1–8) assigned to each domain.
Kevin Zhang, Eric F. Morand, Sarah E. Boyd, François Petitjean, Alberta Hoi, Rachel Koelmeyer, Iolanda Miceli, Julie A. Monk, Hieu T. Nim   +8 more
wiley   +1 more source

Síntese e avaliação da atividade anti-leishmania de chalconas derivadas do 1-naftaldeído [PDF]

, 2006
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Curso de Química.Este trabalho envolveu a síntese, caracterização e avaliação da atividade biológica de chalconas polissubstituídas, que têm suas ...
MASCARELLO, Alessandra MASCARELLO
core  

Development and application of new approaches to study the epidemiology of "mycobacterium ulcerans" disease (Buruli ulcer) in Ghana [PDF]

, 2012
Mycobacterium ulcerans, causing the devastating skin disease Buruli ulcer (BU), has evolved from the fish pathogen M. marinum. By the acquisition of a virulence plasmid (pMUM) a progenitor of M.
Röltgen, Katharina
core   +1 more source

Investigation of Antioxidant, In Silico and In Vivo Antiulcer Activities of New Natural Xanthenone and Antracenone Isolated from Tricholaena teneriffae L. Roots

Molecules
This study aims to investigate the antioxidant, anti-inflammatory, and anti-ulcer properties of two newly isolated natural compounds (1–2) from the hydroalcoholic root extract of Tricholaena teneriffae L.
Henda Keskes, Siwar Soltani, Khaled Hamden, Anthony Abou Dib, Jean-Hugues Renault, Musafau Sanni, Abdel Halim Harrath, Noureddine Allouche, Hichem Ben Salah   +8 more
doaj   +1 more source

Gynecomastia in a Patient Taking Meloxicam—A Case Report

Journal of Primary Care & Community Health, 2020
Gynecomastia is benign enlargement of glandular tissue in the male breast. It occurs due to an imbalance of estrogen and testosterone. It may be unilateral or bilateral.
Steven L. Rosas, Mark E. Deyo-Svendsen, Rachel Z. Oldfather, Michael R. Phillips, T. Andrew Israel, Emily R. Weisenbeck   +5 more
doaj   +1 more source

Determinants of Body Mass Index in Early Systemic Sclerosis: Implications for Nutritional Risk Stratification

Arthritis Care &Research, EarlyView.
Objective Gastrointestinal (GI) involvement can lead to malnutrition in patients with systemic sclerosis (SSc). Body mass index (BMI) remains the most widely used marker to screen nutritional status. We aimed to identify predictors of lower BMI in patients with SSc. Methods Patients with SSc from a prospective US cohort meeting 2013 American College of
Ali Y. Ayla, Meng Zhang, Bingrui Chen, Claudia Pedroza, Brian Skaug, Maureen Mayes, Michael Hughes, Shervin Assassi, Zsuzsanna H. McMahan   +8 more
wiley   +1 more source

Gastroprotective effect of an aqueous suspension of black cumin Nigella sativa on necrotizing agents-induced gastric injury in experimental animals

The Saudi Journal of Gastroenterology, 2008
Background/Aim: Previous studies on "Black seed" or "Black Cumin" Nigella sativa (NS) have reported a large number of pharmacological activities including its anti-ulcer potential.
Al Mofleh Ibrahim, Alhaider Abdulqader, Mossa Jaber, Al-Sohaibani Mohammed, Al-Yahya Mohammed, Rafatullah Syed, Shaik Shaffi   +6 more
doaj