Results 31 to 40 of about 1,418,988 (256)

Association Between Proton Pump Inhibitors (PPI) use and Spontaneous Bacterial Peritonitis (SBP) in patients of Cirrhosis with Sepsis

Pakistan Armed Forces Medical Journal
Objective: To find the relationship between Proton Pump Inhibitors (PPIs) use and development of Spontaneous Bacterial Peritonitis (SBP) in patients of cirrhosis with sepsis. Study Design: Comparative cross-sectional study.
Raja M Waqar Khan, Shazia Nisar, Kamran Ali   +2 more
doaj   +1 more source

The relationship between long-term use of proton pump inhibitor (PPI) and hypomagnesemia in patients with gastroesophageal reflux disease

Caspian Journal of Internal Medicine, 2022
Background: The aim of this study was to evaluate the relationship between the long-term use of PPI and hypomagnesemia in patients with gastroesophageal reflux disease. Methods: This case control study was conducted on GERD patients with long-term use of
Abbas Arj, Zeinab Ghaletakizadeh, Hamidreza Gilassi, Mohsen Razavizadeh   +3 more
doaj  

Effects of stress ulcer prophylaxis in adult ICU patients receiving renal replacement therapy (Sup-Icu RENal, SIREN): Study protocol for a pre-planned observational study

Trials, 2018
Background Proton pump inhibitors are often used in critically ill patients to prevent gastrointestinal bleeding despite limited evidence for benefit.
Joerg C. Schefold, Anders Perner, Theis Lange, Jørn Wetterslev, Matt P. Wise, Mark Borthwick, Stepani Bendel, Frederik Keus, Anne Berit Guttormsen, Søren Marker, Mette Krag, Morten Hylander Møller, for the SUP-ICU investigators   +12 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Safety and effectiveness of Rivaroxaban, Dabigatran and Apixaban in patients with non-valvular atrial fibrillation for stroke prophylaxis

BMC Neurology
Background Atrial fibrillation is the most common arrhythmia that causes an increased risk of thromboembolism. We aimed to evaluate stroke and major bleeding risk in patients with atrial fibrillation using rivaroxaban, apixaban, dabigatran and the ...
Ceyda Tanoğlu, Alevtina Ersoy
doaj   +1 more source

Distribution of proton pump inhibitor usage of all patients and of patients with bleeding events.

, 2015
PPI: proton pump inhibitor.
Dawid L. Staudacher (803801), Ingo Ahrens (209808), Michael Kaiser (803802), Christoph Bode (178879), Christoph Hehrlein (803803)   +4 more
core   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Systematic review: proton pump inhibitor-associated acuteinterstitial nephritis

, 2007
Background: A number of recent case reports and case series suggest that proton pump inhibitors may cause acute interstitial nephritis. Aim: To establish the nature of the relationship (cause or association) between proton pump inhibitor use and ...
Vela, Marcelo F., Sierra, Fernando, Rey, Ma Eugènia, Suarez, M.   +3 more
core   +1 more source

Proton-Pump Inhibitor 제재로 유발된 저칼슘혈증과 저마그네슘혈증

, 2012
A 7-day-old female neonate who visited emergency depar tment due to generalized tonic seizure. Laboratory test results showed hypocalcemia (5.7 mg/dL), hypomagnesemia (0.55 mmol/L), low parathyroid hormone (7.5 pg/mL), and normal 25(OH) vitamin D3 ...
김호성, 권아름, 채현욱, 김예진, 김용혁   +4 more
core   +1 more source