Results 21 to 30 of about 1,335,305 (294)

Oral versus intravenous proton pump inhibitors in preventing re-bleeding for patients with peptic ulcer bleeding after successful endoscopic therapy

open access: yesBMC Gastroenterology, 2012
Background High dose intravenous proton pump inhibitor after endoscopic therapy for peptic ulcer bleeding has been recommended as adjuvant therapy.
Yen Hsu-Heng   +5 more
doaj   +1 more source

Prescribing trends of proton pump inhibitors, antipsychotics and benzodiazepines of medicare part d providers

open access: yesBMC Geriatrics, 2022
Background Proton pump inhibitors, benzodiazepines, and antipsychotics are considered potentially inappropriate medications in older adults according to the American Geriatric Society Beers Criteria, and deprescribing algorithms have been developed to ...
Jennifer M. Toth   +3 more
doaj   +1 more source

Pharmacology of proton pump inhibitors [PDF]

open access: yesCurrent Gastroenterology Reports, 2008
The gastric H,K-ATPase is the primary target for the treatment of acid-related diseases. Proton pump inhibitors (PPIs) are weak bases composed of two moieties, a substituted pyridine with a primary pK(a) of about 4.0, which allows selective accumulation in the secretory canaliculus of the parietal cell, and a benzimidazole with a second pK(a) of about ...
Jai Moo, Shin, George, Sachs
openaire   +2 more sources

Voltage dependence of proton pumping by bacteriorhodopsin mutants with altered lifetime of the m intermediate [PDF]

open access: yes, 2013
The light-driven proton pump bacteriorhodopsin (BR) from Halobacterium salinarum is tightly regulated by the [H+] gradient and transmembrane potential.
Friedrich, Thomas   +7 more
core   +2 more sources

Antiviral therapies against Ebola and other emerging viral diseases using existing medicines that block virus entry [PDF]

open access: yes, 2015
Emerging viral diseases pose a threat to the global population as intervention strategies are mainly limited to basic containment due to the lack of efficacious and approved vaccines and antiviral drugs.
Temperton, Nigel J.   +24 more
core   +1 more source

Proton Pump Inhibitors and Clopidogrel [PDF]

open access: yesCardiovascular Therapeutics, 2010
Proton pump inhibitors are often prescribed for patients on clopidogrel to prevent gastrointestinal bleeding complications. Recent data suggest higher rates of adverse cardiovascular events in patients on proton pump inhibitors and clopidogrel, in comparison to patients on clopidogrel only.
Michael A, Gaglia, Ron, Waksman
openaire   +2 more sources

Proton pump inhibitor-induced Sweet’s syndrome: report of acute febrile neutrophilic dermatosis in a woman with recurrent breast cancer

open access: yesDermatology Practical & Conceptual, 2015
Background: Sweet’s syndrome, also referred to as acute febrile neutrophilic dermatosis, can either occur as an idiopathic disorder or associated with another condition, including cancer, or induced by exposure to a drug.
Philip R. Cohen
doaj   +1 more source

Use of Proton Pump Inhibitors in Hungary: Mixed-Method Study to Reveal Scale and Characteristics

open access: yesFrontiers in Pharmacology, 2020
BackgroundDue to their efficacy and tolerability, utilization of proton pump inhibitors (PPI) has significantly increased worldwide. Parallel to the clinical benefits, potential long-term side effects have been observed, which, along with increasing ...
Mária Matuz   +7 more
doaj   +1 more source

Clopidogrel and proton pump inhibitors [PDF]

open access: yesCanadian Medical Association Journal, 2014
The points raised by Juurlink[1][1] in response to our article[2][2] are worthy of consideration. The release kinetics of the drugs as given in the COGENT trial may have attenuated the potential for a drug–drug interaction.
openaire   +5 more sources

Proton Pump Inhibitor-Related Gastric Mucosal Changes

open access: yesGut and Liver, 2021
Proton pump inhibitors (PPIs) are used worldwide to treat of acid-related disorders such as peptic ulcer and gastroesophageal reflux disease and to prevent gastroduodenal injuries due to nonsteroidal anti-inflammatory drugs.
Gwang Ha Kim
doaj   +1 more source

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