Results 21 to 30 of about 1,418,988 (256)

Use of Proton Pump Inhibitors in Hungary: Mixed-Method Study to Reveal Scale and Characteristics

open access: yesFrontiers in Pharmacology, 2020
BackgroundDue to their efficacy and tolerability, utilization of proton pump inhibitors (PPI) has significantly increased worldwide. Parallel to the clinical benefits, potential long-term side effects have been observed, which, along with increasing ...
Mária Matuz   +7 more
doaj   +1 more source

Therapeutic effect of proton pump inhibitor (Omeprazole) on homogenous leukoplakia with clinico-fractal analysis: A pilot study

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2020
Background: Oral leukoplakia is a white patch or plaque that cannot be characterized clinically or pathologically as any other disease and is not associated with any physical or chemical causative agent except the use of tobacco.
Nivethitha Nagarajan, S Jayachandran
doaj   +1 more source

Proton Pump Inhibitor-Related Gastric Mucosal Changes

open access: yesGut and Liver, 2021
Proton pump inhibitors (PPIs) are used worldwide to treat of acid-related disorders such as peptic ulcer and gastroesophageal reflux disease and to prevent gastroduodenal injuries due to nonsteroidal anti-inflammatory drugs.
Gwang Ha Kim
doaj   +1 more source

Efficacy of Helicobacter pylori eradication therapies: a single centre observational study

open access: yesBMC Gastroenterology, 2001
Background Many Helicobacter pylori eradication regimens have been described. There are little data reporting their efficacy or integration in routine clinical practice. The overall results of eradication therapy in a cohort of patients are described and
Beales Ian LP
doaj   +1 more source

Is proton pump inhibitor therapy always needed in the elderly?

open access: yes, 2015
Is proton pump inhibitor therapy always needed in the ...
Carmelo Scarpignato (1)   +27 more
core   +1 more source

First Proton Pump Inhibitor Prescription Filled After Hospital Discharge.

open access: yes, 2012
First Proton Pump Inhibitor Prescription Filled After Hospital Discharge.
Geoffrey M. Anderson (155717)   +6 more
core   +1 more source

Proton pump inhibitors overuse - consequences among patients

open access: yesJournal of Education, Health and Sport, 2019
Introduction Omeprazole was first proton pump inhibitor (PPI) approved for use by patients. Thirty years have passed since then. Due to their effectiveness, low price and safety proton pump inhibitors have become one of the most frequently prescribed ...
Patrycja Kmiotek   +2 more
doaj   +3 more sources

Eradication of Helicobacter Pylori

open access: yesМедицинский совет, 2015
General idea. The article is a review of data on Helicobacter pylori resistance to antibiotics, the impact of CYP2C19 polymorphism on the metabolism of proton pump inhibitors, and recent findings on the effectiveness of eradication.
V. V. Tsukanov   +3 more
doaj   +1 more source

Transcriptome analysis of proton pump inhibitor–responsive esophageal eosinophilia reveals proton pump inhibitor–reversible allergic inflammation [PDF]

open access: yes, 2015
Esophageal eosinophilia can be proton pump inhibitor (PPI) resistant or responsive, representing two entities known as eosinophilic esophagitis (EoE) and PPI-responsive esophageal eosinophilia (PPI-REE), respectively.
Rothenberg, Marc E   +10 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

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