Results 21 to 30 of about 435 (140)

Efficacy and Safety of Mecobalamin Combined with Prokinetic Agents in the Treatment of Diabetic Gastroparesis: A Meta-Analysis

open access: yesIranian Journal of Public Health, 2021
Background: The aim of the present study was to systematically review the efficacy and safety of mecobalamin combined with prokinetic agents in diabetic gastroparesis (DGP).
Jia Yao   +5 more
doaj  

The experience of using serotonin adipate in intensive care unit for non-surgical patients with gastrointestinal dysfunction

open access: yesКлинический разбор в общей медицине, 2023
Gastrointestinal dysfunction is a disorder often found in critically ill patients that leads to nutritional deficiency resulting in the increase of the number of adverse events during hospitalization, more frequent hospital readmissions and steady ...
Nikolai P. Krotenko, Marina S. Grinenko
doaj   +1 more source

Gastroesophageal Reflux Disease and Alkaline Reflux: the Mechanisms of the Development and Therapeutic Approach

open access: yesGastroenterologìa, 2016
The article deals with gastroesophageal reflux disease (GERD) — a pathology, which occupies a leading place among all acid-related diseases. The main mechanism of GERD is a violation of the motor-evacuation function of the stomach — slowing gastric ...
T.D. Zviahintseva, I.I. Sharhorod
doaj   +1 more source

Impact of Erythromycin as a Prokinetic on the Gut Microbiome in Children with Feeding Intolerance—A Pilot Study

open access: yesAntibiotics, 2023
Background: Studies have demonstrated that the gut microbiome changes upon exposure to systemic antibiotics. There is a paucity of literature regarding impact on the gut microbiome by long-term usage of erythromycin ethyl succinate (EES) when utilized as
Aravind Thavamani   +6 more
doaj   +1 more source

Prokinetic effects of diatrizoate meglumine (Gastrografin®) in a zebrafish for opioid-induced constipation model

open access: yesAnimal Cells and Systems, 2021
Constipation is a common disease that reduces life quality. Drugs of various mechanisms are being developed to resolve this affliction. Intestinal motility can be easily monitored in zebrafish, and so we selected this organism to develop a constipation ...
Dongwoo Kim   +10 more
doaj   +1 more source

Current Options for Improvement of Treatment of Gastroesophageal Reflux Disease

open access: yesGastroenterologìa, 2014
The article is dedicated to the treatment of one of the most common pathologies in gastroenterology — gastroesophageal reflux disease. The use of proton pump inhibitors and their combination with prokinetics is being dwelt.
S.M. Tkach
doaj   +1 more source

The pharmacology of TD-8954, a potent and selective 5-HT4 receptor agonist with gastrointestinal prokinetic properties

open access: yesFrontiers in Pharmacology, 2011
This study evaluated the in vitro and in vivo pharmacological properties of TD-8954, a potent and selective 5-HT4 receptor agonist. TD-8954 had high affinity (pKi = 9.4) for human recombinant 5-HT4(c) (h5-HT4(c)) receptors, and selectivity (> 2,000 ...
David T Beattie   +10 more
doaj   +1 more source

Lidocaine’s Ineffectiveness in Mitigating Lipopolysaccharide-Induced Pain and Peristaltic Effects in Horses

open access: yesAnimals
The present study involved seven horses in a randomized crossover clinical trial to evaluate the effect of lidocaine on horses with induced endotoxemia. Horses received intravenous lidocaine (1.5 mg/kg bolus, followed by 0.05 mg/kg bwt/min) or placebo (0.
Lara Nunes Sousa   +10 more
doaj   +1 more source

Determinants of Body Mass Index in Early Systemic Sclerosis: Implications for Nutritional Risk Stratification

open access: yesArthritis Care &Research, EarlyView.
Objective Gastrointestinal (GI) involvement can lead to malnutrition in patients with systemic sclerosis (SSc). Body mass index (BMI) remains the most widely used marker to screen nutritional status. We aimed to identify predictors of lower BMI in patients with SSc. Methods Patients with SSc from a prospective US cohort meeting 2013 American College of
Ali Y. Ayla   +8 more
wiley   +1 more source

The Effect of Prucalopride on the Completion Rate and Polyp Detection Rate of Colon Capsule Endoscopies

open access: yesClinical Epidemiology, 2022
Ulrik Deding,1,2 Lasse Kaalby,1,2 Gunnar Baatrup,1,2 Morten Kobaek-Larsen,1,2 Marianne Kirstine Thygesen,1,2 Owen Epstein,3 Thomas Bjørsum-Meyer1,2 1Department of Surgery, Odense University Hospital, Svendborg, Denmark; 2Department of Clinical Research ...
Deding U   +6 more
doaj  

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