Results 31 to 40 of about 9,050 (220)
Frontiers in Nutrition, 2023 BackgroundProkinetic agents are currently considered the first-line therapy to improve gastric emptying when feeding intolerance occurred in critically ill adults. In this study, we developed a technique to assess the feasibility of predicting prokinetic
Guangxuan Lv +14 more
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Luminal 5-HT4 receptors—A successful target for prokinetic actions [PDF]
, 2019 The prokinetic effects of 5-HT4 receptor (5-HT4 R) agonists have been utilized clinically for almost three decades to relieve symptoms of constipation. Surprisingly, the mechanism(s) of action of these compounds is still being debated.
Bornstein, JC, Gwynne, RM
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Iranian Journal of Public Health, 2021 Background: The aim of the present study was to systematically review the efficacy and safety of mecobalamin combined with prokinetic agents in diabetic gastroparesis (DGP).
Jia Yao +5 more
doaj
Gastroenterologìa, 2016 The article deals with gastroesophageal reflux disease (GERD) — a pathology, which occupies a leading place among all acid-related diseases. The main mechanism of GERD is a violation of the motor-evacuation function of the stomach — slowing gastric ...
T.D. Zviahintseva, I.I. Sharhorod
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Клинический разбор в общей медицине, 2023 Gastrointestinal dysfunction is a disorder often found in critically ill patients that leads to nutritional deficiency resulting in the increase of the number of adverse events during hospitalization, more frequent hospital readmissions and steady ...
Nikolai P. Krotenko, Marina S. Grinenko
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Use of prokinetic agents in hospitalised adult patients:Protocol for a scoping review
, 2022 Background: Gastrointestinal motility is an important contributor to the effective uptake of water and nutrition. However, it is often impaired in acutely ill hospitalised patients.
Mette Krag +9 more
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Any news from the prokinetic front?
, 2019 PURPOSE OF REVIEW:This review provides an update of recently conducted studies and randomized controlled trials evaluating prokinetic drugs. RECENT FINDINGS:Prokinetic drugs accelerate gastric emptying and, particularly in patients with gastric ...
Chapman, M.J. +2 more
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Current Options for Improvement of Treatment of Gastroesophageal Reflux Disease
Gastroenterologìa, 2014 The article is dedicated to the treatment of one of the most common pathologies in gastroenterology — gastroesophageal reflux disease. The use of proton pump inhibitors and their combination with prokinetics is being dwelt.
S.M. Tkach
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AnimalsThe present study involved seven horses in a randomized crossover clinical trial to evaluate the effect of lidocaine on horses with induced endotoxemia. Horses received intravenous lidocaine (1.5 mg/kg bolus, followed by 0.05 mg/kg bwt/min) or placebo (0.
Lara Nunes Sousa +10 more
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Frontiers in Pharmacology, 2011 This study evaluated the in vitro and in vivo pharmacological properties of TD-8954, a potent and selective 5-HT4 receptor agonist. TD-8954 had high affinity (pKi = 9.4) for human recombinant 5-HT4(c) (h5-HT4(c)) receptors, and selectivity (> 2,000 ...
David T Beattie +10 more
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