Results 31 to 40 of about 21,471 (200)

Metoclopramide-OROS Dispersible Tablets Optimized Formula Bioavailability Study [PDF]

, 2020
BACKGROUND: Bioavailability and bioequivalence studies required by regulations to ensure therapeutic equivalence between a pharmaceutically equivalent test product and a reference product. AIM: This study aimed to evaluate the bioavailability performance
Tanjung, Hari Ronaldo, Samran, Samran
core   +1 more source

Reversible Nonthrombocytopenic Palpable Purpura Associated with Metoclopramide [PDF]

, 1999
OBJECTIVE: To report a case of reversible nonthrombocytopenic palpable purpura associated with metoclopramide. CASE SUMMARY: A 72-year-old white man was admitted for worsening palpable purpura over a two-day period.
Goad, Jeffery A.
core   +1 more source

Current practice and guideline adherence in renal dose adjustment for patients with chronic kidney disease: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed, Ahmed Tehemar, Mohamed Gasimelseed, Ahmed Gharaibeh, Muhammad Abdul Hadi, Kazeem Yusuff, Amani Zidan, Ahmed Awaisu   +7 more
wiley   +1 more source

Effects of metoclopramide on the expression of metalloproteinases and interleukins in left colonic anastomoses. An experimental study [PDF]

Acta Cirúrgica Brasileira, 2015
PURPOSE : To evaluate the effects of metoclopramide on metalloproteinases (MMP) and interleukins (IL) gene expression in colonic anastomoses in rats. METHODS : Eighty rats were divided into two groups for euthanasia on the 3rd or 7th postoperative day ...
Silvana Marques e Silva, Márcio Sousa Jerônimo, Ildinete da Silva-Pereira, Aldo Henrique Tavares, Anamélia Lorenzetti Bocca, João Batista de Sousa   +5 more
doaj   +2 more sources

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Metoclopramide-Induced Acute Dystonic Reaction: A Case Report

Eurasian Journal of Medicine, 2019
The aim of this case report is to draw attention to the frequent occurrence of metoclopramide-induced movement disorders. We report a case of an acute dystonic reaction to metoclopramide in a patient treated for hepatitis A.
Gul Karagoz, Ulker Anadol, Muhterem Yucel, Mehmet Fatih Bektasoglu, Ayten Kadanali, Behiye Dede   +5 more
doaj   +1 more source

Exploring women's experiences and perceptions regarding the pharmacological management of hyperemesis gravidarum: a qualitative study

Journal of Pharmacy Practice and Research, EarlyView.
Abstract Background Hyperemesis gravidarum (HG) is a severe form of nausea and vomiting in pregnancy with potential sequelae including hypovolaemia, electrolyte imbalance, and malnutrition, which can result in adverse maternal–foetal outcomes. Aim To explore Australian women's experiences and perceptions regarding the pharmacological management of HG ...
Timothy R. McNamara, Jacqueline H. Stephens, Stefan C. Kane, Emma L. Healy, Caitlin Neville, Luke E. Grzeskowiak   +5 more
wiley   +1 more source

Case report: metoclopramide induced acute dystonic reaction in adolescent CYP2D6 poor metabolizers

Frontiers in Pharmacology, 2023
Metoclopramide is indicated for the management of gastroesophageal reflux, gastric stasis, nausea, and vomiting. Metoclopramide-induced acute dystonic reactions (MIADRs), along with repetitive involuntary protrusion of the tongue, are well-known ...
Franz-Martin Fink, Marta Bognar, Petra Hengl, Markus Paulmichl, Charity Nofziger   +4 more
doaj   +1 more source

Improving enteral nutrition in patients requiring neurological intensive care unit care: A retrospective study on a novel bedside nasointestinal tube placement technique

Nutrition in Clinical Practice, EarlyView.
Abstract Background This study aimed to develop and assess a bedside nasojejunal tube placement technique designed for resource‐limited settings to address the specific challenges of enteral nutrition (EN) delivery in neurocritical care patients, particularly those at high risk of reflux and aspiration. The technique sought to overcome the drawbacks of
Niuchenglin, Liujuan, Zhushuibing, Dingyuanliang, Yutianhao, Shiguangling   +5 more
wiley   +1 more source

Antiemetic Prophylaxis with Metoclopramide or Metoclopramide and Dexamethasone in high risk surgical patients

, 2013
Background: Postoperative nausea and vomiting (PONV) remains a significant cause of morbidity among patients undergoing general anaesthesia. Identification of patients at high risk for PONV allows targeting prophylaxis at those who will benefit most from
Eyelade, OR, Amanor-Boadu, SD, Awana, EE
core   +2 more sources