Results 121 to 130 of about 5,106 (179)
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Cimetidine—an Antifibrinolytic Agent?
Scandinavian Journal of Gastroenterology, 1983The mucosal fibrinolytic activity was estimated in 14 patients with duodenal ulcer before and after 4 weeks' treatment with cimetidine. A significant reduction in fibrinolytic activity in the corpus and antrum mucosa was found after treatment. In patients with healed ulcer after treatment, the activity was lower than in patients with unhealed ulcers ...
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Antifibrinolytic agents in cardiac surgery: Current controversies
Seminars in Thoracic and Cardiovascular Surgery, 2005Antifibrinolytic agents play a prominent role in adult cardiac surgery. This article is a review of the modern published experience of antifibrinolytic agent use in adult cardiac surgery. The use of tranexamic acid, epsilon-aminocaproic acid, and aprotinin is examined during primary cardiac surgery, deep hypothermic circulatory arrest, reoperative ...
Daniel L, Serna +2 more
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Antifibrinolytic agents in subarachnoid haemorrhage
Journal of Neurology, 1987For many years clinicians have used antifibrinolytic agents to try to reduce rebleeding after subarachnoid haemorrhage. Early studies of their effectiveness produced conflicting results. This paper re-evaluates the available trials and considers benefits in the light of potential complications.
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The effect of antifibrinolytic agents on wound healing
International Journal of Oral and Maxillofacial Surgery, 1988The effect on the tensile strength of healing wounds of 2 of the most commonly used antifibrinolytic substances, tranexamic acid and epsilon-aminocaproic acid, has been studied in white rats. 2 symmetrical linear lines were made on the dorsal skin, in 1 of which was injected 1 ml of the test solution. The incisions were closed with interrupted sutures,
G, Björlin, I M, Nilsson
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Human Placental Transfer of an Antifibrinolytic Agent (AMCA)
Acta Obstetricia et Gynecologica Scandinavica, 1970Abstract. A fibrinolytic inhibitor AMCA (trans p‐aminomethyl cyclohexane carboxylic acid) was given i.v. in a dose of 0.01 g/kg bodyweight to 12 mothers about to be delivered by Caesarean section. Immediately after delivery the concentration of AMCA was determined in the maternal blood and in cord blood.
S, Kullander, I M, Nilsson
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Fibrinolysis, Antifibrinolytic Agents, and Perioperative Considerations
2021Fibrinolysis is an integral component of hemostasis that acts to regulate fibrin formation. Its actions are counterbalanced by the coagulation process, maintaining against excess clot formation or hemorrhage. Excessive release of plasmin through surgery or other means can result in a pathophysiological state characterized by bleeding, inflammation, and
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Antifibrinolytic Agents and Desmopressin as Hemostatic Agents in Cardiac Surgery
The Annals of Pharmacotherapy, 2001OBJECTIVE: To review the use of systemic hemostatic medications for reducing bleeding and transfusion requirements with cardiac surgery. DATA SOURCES: Articles were obtained through computerized searches involving MEDLINE (from 1966 to September 2000).
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The Use of Antifibrinolytic Agents in Spine Surgery
The Journal of Bone and Joint Surgery-American Volume, 2008Antifibrinolytic agents have been shown to decrease the blood loss associated with major orthopaedic surgical procedures. Spine surgery, particularly procedures performed for deformity correction and procedures involving long arthrodesis constructs, can be associated with a large amount of blood loss requiring blood transfusions.
J Brian, Gill +3 more
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ChemInform Abstract: Tranexamic Acid: A Proven Antifibrinolytic Agent
ChemInform, 2010AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
K. Satyavathi +2 more
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A Direct Antifibrinolytic Agent in Major Orthopedic Surgery
Orthopedics, 2004abstract Aprotinin is a potent pharmacological agent that reduces bleeding. In current surgical practices, the rate of blood transfusions has decreased with the use of aprotinin. Recently, studies using aprotinin have been conducted in orthopedic surgery.
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