Results 211 to 220 of about 3,165,964 (235)
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Effects of antifibrinolytic agents on the life span of fibrin sealant
Journal of Surgical Research, 1992Fibrin sealant, a biologic glue consisting of fibrinogen and thrombin, has been used in a variety of surgical procedures. The usefulness of fibrin sealant may be prolonged by the addition of antifibrinolytic agents. This study compared the efficacy of transexamic acid (30 mg/ml), epsilon-aminocaproic acid (25 mg/ml), and aprotinin (3000 KIU/ml) to ...
Thomas L. Matthew+6 more
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A Direct Antifibrinolytic Agent in Major Orthopedic Surgery
Orthopedics, 2004abstract Aprotinin is a potent pharmacological agent that reduces bleeding. In current surgical practices, the rate of blood transfusions has decreased with the use of aprotinin. Recently, studies using aprotinin have been conducted in orthopedic surgery.
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Trinitrophenyl-Derivative of Urinary Trypsin Inhibitor: A Strong Antifibrinolytic Agent
Acta Haematologica, 1987A trinitrophenyl derivative of urinary trypsin inhibitor (TNP-UTI) was found to demonstrate approximately 50 times stronger antiplasmin fibrinolysis than the intact UTI. Almost no change in antitrypsin or antichymotrypsin activity occurred as a result of the UTI modification.
Masugi Maruyama+6 more
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A comparison of antifibrinolytic agents used in hemostatic fibrin sealants
Journal of the American College of Surgeons, 2003Fibrin sealants used as hemostatic and adhesive surgical adjuncts invariably combine fibrinogen and thrombin. The use of plasma-derived products to facilitate hemostasis was first described in 1909. Because the approach relied on in vivo concentrations of fibrinogen and thrombin the quality of the resulting fibrin clot was poor.
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The plasmin inhibition by synthetic antifibrinolytic agents in relation to the type of substrate
Biochimica et Biophysica Acta (BBA) - Enzymology, 1968The inhibitory effect of synthetic antifibrinolytic agents: e-aminocaproic acid, p-aminomethyl benzoic acid and the active isomer of 1,4-aminomethyl cyclohexane carboxylic acid on plasmin (EC 3.4.4.14), acting on various substrates, was studied. All the inhibitors had a very weak effect, if any at all, on casein and fibrinogen proteolysis by plasmin ...
Hanna Łukasiewicz+3 more
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Antifibrinolytic agents for paediatric scoliosis surgery: a systematic review and meta-analysis
European spine journal, 2019S. Karimi+5 more
semanticscholar +1 more source
Antifibrinolytic Agents Reduce Blood Loss During Pediatric Vertebral Column Resection Procedures
Spine, 2012P. Newton+7 more
semanticscholar +1 more source