Results 211 to 220 of about 3,165,964 (235)
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Effects of antifibrinolytic agents on the life span of fibrin sealant

Journal of Surgical Research, 1992
Fibrin sealant, a biologic glue consisting of fibrinogen and thrombin, has been used in a variety of surgical procedures. The usefulness of fibrin sealant may be prolonged by the addition of antifibrinolytic agents. This study compared the efficacy of transexamic acid (30 mg/ml), epsilon-aminocaproic acid (25 mg/ml), and aprotinin (3000 KIU/ml) to ...
Thomas L. Matthew   +6 more
openaire   +3 more sources

A Direct Antifibrinolytic Agent in Major Orthopedic Surgery

Orthopedics, 2004
abstract Aprotinin is a potent pharmacological agent that reduces bleeding. In current surgical practices, the rate of blood transfusions has decreased with the use of aprotinin. Recently, studies using aprotinin have been conducted in orthopedic surgery.
openaire   +3 more sources

Trinitrophenyl-Derivative of Urinary Trypsin Inhibitor: A Strong Antifibrinolytic Agent

Acta Haematologica, 1987
A trinitrophenyl derivative of urinary trypsin inhibitor (TNP-UTI) was found to demonstrate approximately 50 times stronger antiplasmin fibrinolysis than the intact UTI. Almost no change in antitrypsin or antichymotrypsin activity occurred as a result of the UTI modification.
Masugi Maruyama   +6 more
openaire   +3 more sources

A comparison of antifibrinolytic agents used in hemostatic fibrin sealants

Journal of the American College of Surgeons, 2003
Fibrin sealants used as hemostatic and adhesive surgical adjuncts invariably combine fibrinogen and thrombin. The use of plasma-derived products to facilitate hemostasis was first described in 1909. Because the approach relied on in vivo concentrations of fibrinogen and thrombin the quality of the resulting fibrin clot was poor.
openaire   +3 more sources

The plasmin inhibition by synthetic antifibrinolytic agents in relation to the type of substrate

Biochimica et Biophysica Acta (BBA) - Enzymology, 1968
The inhibitory effect of synthetic antifibrinolytic agents: e-aminocaproic acid, p-aminomethyl benzoic acid and the active isomer of 1,4-aminomethyl cyclohexane carboxylic acid on plasmin (EC 3.4.4.14), acting on various substrates, was studied. All the inhibitors had a very weak effect, if any at all, on casein and fibrinogen proteolysis by plasmin ...
Hanna Łukasiewicz   +3 more
openaire   +3 more sources

Antifibrinolytic agents for paediatric scoliosis surgery: a systematic review and meta-analysis

European spine journal, 2019
S. Karimi   +5 more
semanticscholar   +1 more source

Antifibrinolytic Agents Reduce Blood Loss During Pediatric Vertebral Column Resection Procedures

Spine, 2012
P. Newton   +7 more
semanticscholar   +1 more source

A systematic review of the use of antifibrinolytic agents in pediatric surgery and implications for craniofacial use

Pediatric surgery international (Print), 2012
Marten Basta   +2 more
semanticscholar   +1 more source

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