Results 121 to 130 of about 428,404 (336)

Single‐Cell Analysis Reveals that Vitamin C Inhibits Bone Metastasis of Renal Cancer via Cell Cycle Arrest and Microenvironment Remodeling

open access: yesAdvanced Science, EarlyView.
3D‐cultured renal cancer cells exhibit stem‐like phenotypes and are more efficient in generating bone metastases. Vitamin C treatment can suppress the development of bone metastasis. Single‐cell transcriptomic analysis reveals that vitamin C inhibits metastasis by inducing tumor cell cycle arrest, suppressing osteoclast differentiation, and reducing ...
Jianye Zhang   +17 more
wiley   +1 more source

Peptide‐Based Biomaterials as a Promising Tool for Cancer Radiotherapy

open access: yesAdvanced Science, EarlyView.
This review provides a systematic overview of peptide‐based biomaterials in tumor radiotherapy, covering their roles as both radiosensitizers and radiopharmaceuticals. Peptide‐based radiosensitizers are generally divided into three categories: peptides as direct radiosensitizers, peptides as carriers of radiosensitizers, and targeted‐peptide‐modified ...
Qian Wang, Xinhui Chu, Jianfeng Liu
wiley   +1 more source

Machine Learning‐Enhanced Nanoparticle Design for Precision Cancer Drug Delivery

open access: yesAdvanced Science, EarlyView.
Machine Learning (ML) is revolutionizing cancer nanomedicine by optimizing nanoparticle (NP) design and drug delivery. This review summarizes ML applications across all stages of NP drug delivery, along with a discussion of ongoing challenges and future directions.
Qingquan Wang   +5 more
wiley   +1 more source

Antifungal resistance in dermatology

open access: yesIndian Journal of Dermatology, 2018
Cutaneous fungal infections affect more than one-fourth of world's population. The pathogenesis and severity of fungal infection depend on various immunological and nonimmunological factors. The rampant use of antifungal therapy in immunocompromised individuals marked the onset of antifungal drug resistance.
Naveen Narayanshetty Kikkeri   +2 more
openaire   +3 more sources

Fabrication of Dual Photodynamic Enhanced Antimicrobial CDs@ZIF‐8/Polycaprolactone/Ethyl Cellulose Nanofibrous Films for Fruit Preservation

open access: yesAdvanced Science, EarlyView.
Carbon dots (CDs) are incorporated into ZIF‐8 to synthesize CDs@ZIF‐8 nanocomposites, which exhibit dual photodynamic enhanced antimicrobial properties. This enhancement is due to the narrow bandgap of CDs@ZIF‐8, which facilitates interfacial electronic transfer, resulting in increased reactive oxygen species. Microfluidic blow spinning is then used to
Yongrui Ti   +10 more
wiley   +1 more source

UTX Responds to Nanotopography to Suppress Macrophage Inflammatory Response by Remodeling H3K27me3 Modification

open access: yesAdvanced Science, EarlyView.
Compared with those on the pTi surface, macrophages on the TNTs surface present reduced myosin II contractility, which facilitates the nuclear translocation of the UTX. This reduction decreases the enrichment of the repressive H3K27me3 histone modification at the Abca1 gene locus, which promotes the transcription and protein expression of ABCA1 ...
Hengji Jia   +8 more
wiley   +1 more source

THE ANTIFUNGAL ACTIVITY OF ANTIBIOTIC XG 1 [PDF]

open access: bronze, 1949
Gladys L. Hobby   +3 more
openalex   +1 more source

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