Results 191 to 200 of about 645,736 (382)

Design, synthesis, and in vitro antifungal evaluation of novel triazole derivatives bearing alkynyl side chains

, 2018
Tingjunhong Ni, Lei Pang, Zhan Cai, Fei Xie, Zichao Ding, Yumeng Hao, Ran Li, Shichong Yu, Xiaoyun Chai, Ting Wang, Yongsheng Jin, Dazhi Zhang, Yuanying Jiang   +12 more
openalex   +1 more source

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

Advanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori, Takumi Iritani, Toshikaze Chiba, Takehiro Jimbo, Michio Katano, Kansuporn Kamataki, Ryoichi Yokoyama, Eigo Shimizu, Kiminori Kimura, Satoshi Yamzaki, Seiya Imoto, Yoichi Furukawa, Atsushi Miyajima, Yoshikazu Johmura, Makoto Nakanishi   +23 more
wiley   +1 more source

In vitro Evaluation of Antifungal Activity of Balanites aegyptiaca Del.

, 2020
Bhawana Sharma
openalex   +1 more source

Azole antifungal resistance in Aspergillus fumigatus: 2008 and 2009 [PDF]

, 2010
Ahmed S. Bueid, S. J. Howard, Caroline B. Moore, Malcolm Richardson, Elizabeth Harrison, Paul Bowyer, David W. Denning   +6 more
openalex   +1 more source

Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance

Advanced Science, EarlyView.
In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei, Junbin Chen, Chuang Liu, DanDan Liu, Meida Du, Shengfeng He, Wenyu Cheng, Vijai Bhadauria, You‐Liang Peng, Wangsheng Zhu   +9 more
wiley   +1 more source

Kinetic Analysis of the Antifungal Activity of Heated Scallop-Shell Powder against Trichophyton and Its Possible Application to the Treatment of Dermatophytosis

, 2006
Jun Sawai, Hirokazu Shiga
openalex   +2 more sources

Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation to CYP2C19 genotype [PDF]

, 2009
Ina M. Scholz, Heike Oberwittler, Klaus‐Dieter Riedel, Jürgen Burhenne, Johanna Weiß, Walter E. Haefeli, Gerd Mikus   +6 more
openalex   +1 more source

Unravelling the antifungal mode of action of curcumin by potential inhibition of CYP51B: A computational study validated in vitro on mucormycosis agent, Rhizopus oryzae

, 2021
Jignesh Prajapati, Priyashi Rao, Lipi Poojara, Dweipayan Goswami, Dhaval Acharya, Saumya Patel, Rakesh Rawal   +6 more
openalex   +1 more source

The antifungal pipeline: a reality check

Nature reviews. Drug discovery, 2017
J. Perfect
semanticscholar   +1 more source

Development of Endogenous Protein Probes for Characterizing Surface Proteins and Cellular Interactors of Extracellular Vesicles

Advanced Science, EarlyView.
The proximity labeling enzyme APEX2 is displayed on extracellular vesicle (EV) surfaces via genetic fusion with EV‐sorting scaffolds, enabling in situ biotinylation of native surface proteins, adsorbed corona components, and interacting cellular proteins.
Wenyi Zheng, Metoboroghene Mowoe, Wenqing Hou, Daniel W. Hagey, Koshi Imami, Samir EL Andaloussi   +5 more
wiley   +1 more source