Results 281 to 290 of about 428,404 (336)

EPHA5 regulates antifungal innate immunity by phosphorylating EPHB2 and Dectin-1. [PDF]

PLoS Pathog
Gao R, Wang H, Cui Z, Du Y, He R, Feng L, Zeng B, Li Y, Huang G, Pan T, Wang Y, Yi M, Wang C.   +12 more
europepmc   +1 more source

Modular, Tricomponent, and Concurrent One‐Pot Synthesis of Libraries of γ‐Keto Sulfones and γ‐Keto Phosphine Oxides using Brønsted Acidic Eutectic Mixtures

ChemSusChem, EarlyView.
This study presents a sustainable, metal‐free, one‐pot synthesis of γ‐keto sulfones and phosphine oxides using a ChCl/p‐TSA·H2O eutectic mixture. The method enables regioselective CC and CX bond formation under mild conditions, aligning with Green Chemistry Principles.
Marina Ramos‐Martín, Joaquín García‐Álvarez, Alejandro Presa Soto   +2 more
wiley   +1 more source

Antifungal Activity of 5-Fluorouridine Against <i>Candida albicans</i> and <i>Candida parapsilosis</i> Based on Virulence Reduction. [PDF]

Molecules
Lenarczyk E, Oleksiak D, Janeczko M.
europepmc   +1 more source

Remolding Waste Liquid From the Zeolite Synthesis Process Into Wrinkled Dressings for Diabetic Wound Therapeutics With Immunomodulation

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Waste liquid from natural clay‐to‐zeolite synthesis is remolded into a metal‐wrinkled dressing showing outstanding hemostatic, antibacterial, and wound‐healing effects. Chronic wounds resulting from diabetes are among the most common complications in diabetic patients.
Hanlin Yao, Xinyu You, Songqi Wu, Yunhao Wang, Di Hu, Yongsheng Ma, Jun Luo, Jie Qiu, Lihua Zhou   +8 more
wiley   +1 more source

Exploring the Potential of s-Triazine Derivatives as Novel Antifungal Agents: A Review. [PDF]

Pharmaceuticals (Basel)
Liao H, Liu M, Wang M, Zhang D, Hao Y, Xie F.   +5 more
europepmc   +1 more source

Early administration of SGLT2 inhibitors in hospitalized patients: A practical guidance from the current evidence

ESC Heart Failure, EarlyView.
Abstract Sodium‐glucose cotransporter‐2 (SGLT2) inhibitors represent one of the main cornerstones of heart failure treatment. Nevertheless, while the cardiovascular beneficial effects of these drugs have been clearly demonstrated by several clinical trials, in clinical practice, it remains challenging to identify the appropriate timing to start SGLT2 ...
Ruggero Mazzotta, Manuel Garofalo, Samuele Salvi, Matteo Orlandi, Gianluca Marcaccini, Pietro Susini, Luca Checchi, Alberto Palazzuoli, Carlo Di Mario, Maurizio Pieroni, Matteo Beltrami   +10 more
wiley   +1 more source

Protease production by Serratia liquefaciens NRC1 using fish gut waste as a sustainable approach to antimicrobial peptide generation and combating Candida auris acquired resistance. [PDF]

Microb Cell Fact
Ismail SA, Shalaby HM, Hassan AA, Mahmoud M, Fayed B.   +4 more
europepmc   +1 more source

Toward the Synthesis of 3,3‐Difluoro Deaminated Sialic Acid (C3DFKDN)

European Journal of Organic Chemistry, EarlyView.
The synthesis of protected C3‐difluoro KDN (C3DFKDN), an unnatural derivative of the sialic acid member, KDN, and key building block for KDN‐based chemical probes, is reported. Its 12‐step synthetic route starts from commercially available methyl d‐mannopyranoside and key steps include a Reformatsky reaction with ethyl bromodifluoroacetate, alkylation ...
Lemeng Chao, Tom Wennekes
wiley   +1 more source

Epidemiological characteristics, antifungal susceptibility, and mortality factors of candidemia in adults at a tertiary teaching hospital in Zunyi, China (2016-2023). [PDF]

BMC Infect Dis
Chen X, Shen M, Feng Q, Yang G, Tian R, Yao S, Zha H.   +6 more
europepmc   +1 more source

Molecular iodine‐mediated functionalization of α‐Carbonyl Sulfoxonium ylides with Thiocyanates, Xanthates and Dithiocarbamates

European Journal of Organic Chemistry, Accepted Article.
In this work, we present a straightforward, rapid, and cost‐effective protocol for synthesizing three distinct classes of α‐functionalized sulfoxonium ylides—α‐xanthate, α‐thiocyanate, and α‐dithiocarbamate—via molecular iodine‐mediated reactions. This method demonstrates broad substrate tolerance, including heterocycles and steroids, delivering 25 ...
Kauê C. Capellaro, Antonio C. B. Burtoloso   +1 more
wiley   +1 more source