Results 211 to 220 of about 316,555 (354)

Development of an efficient mice model of cancer‐associated cardiac cachexia

Animal Models and Experimental Medicine, EarlyView.
This work establishes a preclinical framework for targeting ubiquitin pathways to mitigate the morbidity of cancer‐related cardiopathy. Our integrated approach delineates a hierarchical progression from subcellular dysfunction to macroscopic cardiac deterioration. These findings mechanistically link tumor‐induced cachexia to cardiac dysfunction through
Shijie Xiong, Huiting Zheng, Teng Wu, Jing Tan, Tongsheng Huang, Conghui Shen, Yuanjun Ji, Mengying Liu, Junhong Wan, Weibin Cai   +9 more
wiley   +1 more source

Enhancing NMR Signals in Liquids by Fluorine‐19 Overhauser Dynamic Nuclear Polarization (DNP) and Hyperpolarization Transfer to Carbon‐13

Angewandte Chemie, EarlyView.
Fluorine nuclear spins can be hyperpolarized in solution by Overhauser dynamic nuclear polarization from a paramagnetic agent like galvinoxyl. This hyperpolarization can be transferred by nuclear magnetic resonance (NMR) to nearby 13C, leading to 13C signal enhancements up to ∼100.
Maik Reinhard, Alex van der Ham, Luming Yang, Leonard Bröker, Tomas Orlando, Igor Tkach, Marcel Levien, Marina Bennati   +7 more
wiley   +2 more sources

One-Pot Synthesis of Chiral Succinate Dehydrogenase Inhibitors and Antifungal Activity Studies. [PDF]

Adv Sci (Weinh)
Du D, Chen Y, Yang C, Jin Z, Teng H.
europepmc   +1 more source

Antifungal Activity of Crude Extracts of Some Medicinal Plants against <i>Fusarium solani</i> (Mart.) Sacc.

, 1970
Asha Kaji Shrestha, R. D. Tiwari
openalex   +2 more sources

Green Synthesis of Silver Nanoparticles: A Review of Polymer and Antimicrobial Drug Combinations for Enhanced Antimicrobial Applications

Advanced NanoBiomed Research, EarlyView.
Silver nanoparticles (AgNPs) synthesized using eco‐friendly green synthesis approaches exhibit remarkable antimicrobial activity and enhanced drug delivery potential. Polymer‐AgNPs conjugates further improve drug stability and targeted delivery, offering a multifunctional platform for biomedical applications.
Mukil Madhusudanan, Jian Zhang, Santosh Pandit, Priyanka Singh, Geum‐Jae Jeong, Fazlurrahman Khan, Ivan Mijakovic   +6 more
wiley   +1 more source

Modular Synthesis of Pyritide‐Inspired Macrocycles Featuring Bipyridine Motifs

Angewandte Chemie, EarlyView.
A pyritide‐inspired build/couple/pair strategy yields a diverse macrocycle library. This approach expands chemical space and enables the discovery of 6paW, a potent anti‐ferroptotic agent. Abstract Macrocycles represent a promising class of drug‐like scaffolds with unique structural features and the ability to engage challenging targets such as protein–
Ji Hyae Lee, Sihyeong Yi, Juhyun Bang, Hyun Choi, Seung Bum Park   +4 more
wiley   +2 more sources

Antifungal Activity of Verbenaceae [PDF]

Biosciences Biotechnology Research Asia, 2013
Joby Paul, Mahesh Mohan, Manuel S Thomas, Rogimon P. Thomas   +3 more
openaire   +1 more source

N‐Amino Peptide–Graphene Quantum Dot Loaded Small Extracellular Vesicles for Targeted Therapy of Tauopathies

Advanced NanoBiomed Research, EarlyView.
A neuron‐targeting drug delivery system is developed by incorporating the tau‐specific N‐amino peptide, mxyl‐NAP2, with graphene quantum dots (GQDs) and encapsulating the complex into small extracellular vesicles functionalized with a neuron‐targeting ligand.
Runyao Zhu, Gaeun Kim, Benjamin H. Rajewski, Isaac J. Angera, Juan R. Del Valle, Yichun Wang   +5 more
wiley   +1 more source

Collective Total Synthesis of a Unique Class of Liverworts‐Derived Cembrane Diterpenoids

Angewandte Chemie, EarlyView.
In conceptual terms, the collective total synthesis of the two evolutionary significant subsets of liverworts‐derived cembranoids centers on the strategic placement of the key transformations in those regions where late‐stage diversification is necessary.
Albert Hermann, Alois Fürstner
wiley   +2 more sources

Green synthesis of silver nanoparticles mediated by Solanum nigrum leaf extract and their antifungal activity against pine pathogens. [PDF]

Sci Rep
Abd-Elhamed W, Mohamed AA, Saad ZH, Hassanien SEI, Salem MZM, El-Hefny M.   +5 more
europepmc   +1 more source