Results 31 to 40 of about 157,410 (169)

Antifungal Activity of a Library of Aminothioxanthones

Antibiotics, 2022
Fungal infections are one of the main causes of mortality and morbidity worldwide and taking into account the increasing incidence of strains resistant to classical antifungal drugs, the development of new agents has become an urgent clinical need. Considering that thioxanthones are bioisosteres of xanthones with known anti-infective actions, their ...
Joana Cardoso, Joana Freitas-Silva, Fernando Durães, Diogo Teixeira Carvalho, Luís Gales, Madalena Pinto, Emília Sousa, Eugénia Pinto   +7 more
openaire   +3 more sources

Novel Antifungal Compounds Discovered in Medicines for Malaria Venture’s Malaria Box

mSphere, 2018
Similarities in fungal and animal cells make antifungal discovery efforts more difficult than those for other classes of antimicrobial drugs. Currently, there are only three major classes of antifungal drugs used for the treatment of systemic fungal ...
Eric H. Jung, David J. Meyers, Jürgen Bosch, Arturo Casadevall   +3 more
doaj   +1 more source

Nanoemulsion Increases the Antifungal Activity of Amphotericin B against Four Candida auris Clades: In Vitro and In Vivo Assays

Microorganisms, 2023
Candida auris is an emerging yeast of worldwide interest due to its antifungal resistance and mortality rates. The aim of this study was to analyse the in vitro and in vivo antifungal activity of a nanoemulsion loaded with amphotericin B (NEA) against ...
Gabriel Davi Marena, Alba Ruiz-Gaitán, Victor Garcia-Bustos, María Ángeles Tormo-Mas, Jose Manuel Pérez-Royo, Alejandro López, Patricia Bernarbe, María Dolores Pérez Ruiz, Lara Zaragoza Macian, Carmen Vicente Saez, Antonia Avalos Mansilla, Eulogio Valentín Gómez, Gabriela Corrêa Carvalho, Tais Maria Bauab, Marlus Chorilli, Javier Pemán   +15 more
doaj   +1 more source

Antifungal Activities of New Coumarins [PDF]

Molecules, 2012
Newly synthesized coumarins 4-((5-mercapto-4-phenyl-4H-1,2,4-triazol-3-yl)-methoxy)-2H-chromen-2-one and 4-((5-(phenylamino)-1,3,4-thiadiazol-2-yl)-methoxy)-2H-chromen-2-one were tested against selected types of fungi and showed significant activities.
Ahmed A. Al-Amiery, Abdul Amir Hassan Kadhum, Abu Bakar Mohamad   +2 more
openaire   +3 more sources

Evaluating the in vitro anti-diabetic activity of Bryonia dioica root extracts supported by molecular docking analysis

Digital Chinese Medicine
Objective: To evaluate the in vitro anti-diabetic effects of Bryonia dioica roots extracts, including water-acetone extracts and their ethyl acetate and butanol fractions, and chloroform-methanol extracts. Methods: The total phenolic, flavonoid, flavonol,
Fekhikher Zohra, Benariba Nabila, Radia Brixi Gormat, Hassain Reda, Abdelli Imen, Z. Sekkal Fatima, Kachekouche Youssouf, Taibi Warda, Brikci Sohayb Bekkal, Terki Mohammed, Benramdane Hanane, Adjdir Sara   +11 more
doaj   +1 more source

REMEDIATION OF ONYCHOMYCOSIS USING BIONANOTECHNOLOGY [PDF]

Journal of Environmental Science
Onychomycosis is a common chronic fungal infection of the nails that causes discoloration and/or thickening of the nail plate. It is challenging to treat and is associated with high recurrence rate and require lengthy duration of treatment, which poses a
Heba Basheer, Mehreshan El Mokadem, Mohamed El Sayed, Mona El Fangary, Amal Mekawey, Marwa Fathi   +5 more
doaj   +1 more source

Gel potential of red onion (Allium cepa L.) ethanol extract as antifungal cause tinea pedis

Journal of Pharmacy and Bioallied Sciences, 2020
Introduction: Tinea pedis is a dermatophyte infection of human feet, especially between the fingers and soles of the feet. Tinea pedis is caused by a fungal infection of Trichophyton rubrum.
Erza Genatrika, Elza Sundhani, Mayang I Oktaviana   +2 more
doaj   +1 more source

Physiological Analysis (Monitoring of Germinal and Biometric Parameters) of Abelmoschus esculentus L. Seeds under the Effect of 100 mM and 150 mM NaCl

Biology and Life Sciences Forum
Abelmoschus esculentus L. is a plant of legume origin; it is used in several areas of nutrition, industry and medicine. This study was proposed in order to understand the adaptation mechanisms of the seeds of this species under the effect of NaCl ...
Khedidja Dahli, Houria Medjdoub
doaj   +1 more source

Antifungal Activity of Micafungin in Serum [PDF]

Antimicrobial Agents and Chemotherapy, 2009
ABSTRACT We have evaluated the antifungal activity of micafungin in serum by using the disk diffusion method with serum-free and serum-added micafungin standard curves. Serum samples from micafungin-treated patients have been shown to exhibit adequate antifungal activity, which was in proportion to both the applied dose and the actual ...
Jun, Ishikawa, Tetsuo, Maeda, Itaru, Matsumura, Masato, Yasumi, Hidetoshi, Ujiie, Hiroaki, Masaie, Tsuyoshi, Nakazawa, Nobuo, Mochizuki, Satoshi, Kishino, Yuzuru, Kanakura   +9 more
openaire   +2 more sources

Antibacterial and antifungal activity of the liverwort (Ptilidium pulcherrimum) methanol extract [PDF]

Archives of Biological Sciences, 2010
The antimicrobial activity of the methanol extract from the liverwort, Ptilidium pulcherrimum was evaluated against five bacterial and six fungal species. In vitro antibacterial activity was assessed by disc diffusion and microdilution methods.
Veljić M., Ćirić Ana, Soković Marina, Janaćković P., Marin P.D.   +4 more
doaj   +1 more source