Results 201 to 210 of about 502,199 (230)

Reducing copper inputs through integration of essential oil‐based formulations: laboratory and 2‐year vineyard evaluation against Plasmopara viticola

open access: yesPest Management Science, EarlyView.
Combining an essential oil (EO)‐based formulation with copper effectively controls Plasmopara viticola. Field trials showed a 92–99% protection with lower copper inputs, achieving a 45% copper reduction without compromising efficacy. This approach supports EO‐based products as sustainable alternatives for grapevine downy mildew management.
Greta Dardani   +2 more
wiley   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

open access: yesPhytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko   +3 more
wiley   +1 more source

Infection risk in rheumatoid arthritis patients treated with biologic and targeted therapies

open access: yesRheumatology &Autoimmunity, EarlyView.
In this context, infections associated with each biologic and targeted drug are summarized to inform the stratification of RA patients, including the characteristics of the susceptible patients and their concomitant therapy. We aim to provide a benefit‐risk analysis for clinical decision, and vital indications for the prevention of highly correlated ...
Lujing Wang, Jieshi Lin, Jie Qian
wiley   +1 more source

Establishment of a Human Cell‐Based In Vitro Test System for Investigating and Evaluating Cytotoxic and Immunomodulatory Effects of Indoor Mold

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Mold growth in damp indoor environments is a widespread problem associated with respiratory health effects, though causal mechanisms remain incompletely understood. We established a human cell‐based in vitro test system using bronchial epithelial cells (NuLi‐1) and macrophages (THP‐1) to assess inhalation toxicity and immunomodulatory effects ...
Anja Wolff   +8 more
wiley   +1 more source

Commercial Product Based on Metarhizium Anisopliae Affects Survival, Midgut Morphology, and Behavior in the Stingless Bee Scaptotrigona depilis (Hymenoptera: Apidae)

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Brazilian social stingless bees are important pollinators and producers of honey, wax, royal jelly, propolis, and other products. These species are experiencing a population decline, attributed to different factors, such as the excessive use of pesticides.
Andressa Santoro   +9 more
wiley   +1 more source

Cotton Farming Pesticides Affect Ileal Microbiota Activity and Expression of Virulome but Not Resistome or Metabolic Pathways in a Sedentary Wild Passerine

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT The increased use of agrochemicals to enhance crop production has had detrimental environmental effects including implication in the sharp decline of North American farmland‐breeding birds. Here, using a combination of deep shotgun metatranscriptomics and pesticide exposure data, we sought to assess whether exposure to cotton (Gossypium spp ...
Serguei V. Drovetski   +4 more
wiley   +1 more source

“White and Clear” (WaC): A tunable hydrophilic tissue clearing strategy for multi‐species 3D imaging

open access: yesVIEW, EarlyView.
Optical tissue clearing methods help scientists make tissues transparent to image structures deep inside organs in 3D, but many existing techniques are limited in performance and difficulty. In this study, we developed an optimized clearing method called WaC (White and Clear), which improves upon existing techniques by combining efficient tissue ...
Vicente Llorente   +12 more
wiley   +1 more source

Strategies for enhancing sensitivity in lateral flow assays

open access: yesVIEW, EarlyView.
Lateral flow assays (LFAs) are essential for cost‐effective, rapid point‐of‐care diagnostics. However, conventional colourimetric LFAs often lack the sensitivity required for low‐abundance biomarkers. This review evaluates six enhancement strategies: flow modulation, sample preconcentration, advanced reporters, chemical signal amplification, structural
Aylar Eslami Saed   +3 more
wiley   +1 more source

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

open access: yesVIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore   +5 more
wiley   +1 more source

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