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ANTIFUNGAL PROPHYLAXIS IN IMMUNOCOMPROMISED PATIENTS [PDF]

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2016
Invasive fungal infections (IFIs) represent significant complications in patients with hematological malignancies. Chemoprevention of IFIs may be important in this setting, but most antifungal drugs have demonstrated poor efficacy, particularly in the ...
Lourdes Vazquez
doaj   +4 more sources

Diagnosis and Antifungal Prophylaxis for COVID-19 Associated Pulmonary Aspergillosis [PDF]

open access: yesAntibiotics, 2022
The COVID-19 pandemic has redemonstrated the importance of the fungal-after-viral phenomenon, and the question of whether prophylaxis should be used to prevent COVID-19-associated pulmonary aspergillosis (CAPA).
Armani M. Hawes, Nitipong Permpalung
doaj   +3 more sources

Invasive Aspergillosis among Lung Transplant Recipients during Time Periods with Universal and Targeted Antifungal Prophylaxis—A Nationwide Cohort Study [PDF]

open access: yesJournal of Fungi, 2023
The optimal prevention strategy for invasive aspergillosis (IA) in lung transplant recipients (LTXr) is unknown. In 2016, the Danish guidelines were changed from universal to targeted IA prophylaxis. Previously, we found higher rates of adverse events in
Cornelia Geisler Crone   +7 more
doaj   +2 more sources

The Impact of Antifungal Prophylaxis in Lung Transplant Recipients

open access: yesAnnals of the American Thoracic Society, 2021
Abstract Rationale Many lung transplant centers prescribe antifungal medications after transplantation to prevent invasive fungal infections (IFIs); however, the effectiveness of antifungal prophylaxis at reducing the risk of all-cause mortality or IFI has not been established.
Raymund Razonable   +2 more
exaly   +4 more sources

Antifungal prophylaxis among critically ill COVID-19 patients: a meta-analysis and systematic review [PDF]

open access: yesBMC Infectious Diseases
Background COVID-19-associated pulmonary aspergillosis (CAPA) affects a significant proportion of patients admitted to the ICU and is associated with increased mortality, underscoring the need for effective prophylaxis.
Huaiya Xie   +6 more
doaj   +2 more sources

Case Report: Invasive fungal infection after anti-CD19 CAR-T cell therapy. Implication for antifungal prophylaxis

open access: yesFrontiers in Immunology, 2023
CAR-T therapy has revolutionized the treatment of relapsed/refractory B-cell malignancies. Patients who are receiving such therapy are susceptible to an increased incidence of infections due to post-treatment immunosuppression.
Mauro di Ianni   +2 more
exaly   +3 more sources

Effectiveness of high efficiency particulate (HEPA) air condition combined with the antifungal prophylaxis on incidence, morbidity and mortality of invasive fungal infections in patients with acute myeloid leukemia: a retrospective single-center study [PDF]

open access: yesFrontiers in Oncology
IntroductionOur monocentric and retrospective study aimed to investigate the clinical effectivity of HEPA filters in combination with the antifungal drug prophylaxis in patients with AML undergoing intensive chemotherapy and allogeneic stem cell ...
Linda Preyer   +14 more
doaj   +2 more sources

Reply: Antifungal Prophylaxis. [PDF]

open access: yesAnn Am Thorac Soc, 2021
Pennington KM, Razonable RR, Kennedy CC.
europepmc   +4 more sources

Nebulized Amphotericin B in Mechanically Ventilated COVID-19 Patients to Prevent Invasive Pulmonary Aspergillosis: A Retrospective Cohort Study

open access: yesCritical Care Explorations, 2022
IMPORTANCE:. Despite high mortality rates of COVID-19-associated pulmonary aspergillosis (CAPA) in the ICU, antifungal prophylaxis remains a subject of debate.
Max Melchers, MD   +9 more
doaj   +1 more source

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