Results 51 to 60 of about 214,511 (232)

Isavuconazole—Animal Data and Clinical Data

Journal of Fungi, 2020
The treatment of invasive fungal infections has deeply evolved in the last years with the inclusion of new antifungals, mainly new azoles (i.e., posaconazole, isavuconazole), to the therapeutic armamentarium.
Livio Pagano, Chiara Cattaneo, Martina Quattrone, Margherita Oberti, Maria Mazzitelli, Enrico Maria Trecarichi   +5 more
doaj   +1 more source

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood, Jacinta R. Macdonald, Christian Anzenhofer, Tina S. Skinner‐Adams, Robert C. Reid, Thomas Kurz, David P. Fairlie, Katherine T. Andrews   +7 more
wiley   +1 more source

'Real-life' analysis of the role of antifungal prophylaxis in preventing invasive aspergillosis in AML patients undergoing consolidation therapy: Sorveglianza Epidemiologica Infezioni nelle Emopatie (SEIFEM) 2016 study

, 2019
Background: We evaluated the incidence of proven/probable invasive aspergillosis (IA) and the role of antifungal prophylaxis (AP) in a 'real-life' setting of patients with AML receiving intensive consolidation therapy.
Verga, L, Del Principe, Maria Ilaria, Veggia, Barbara, Fanci, R, Aversa, F, Candoni, Anna, Veggia, B, Melillo, L, Marchesi, F, Tumbarello, M, Potenza, Leonardo, Pagano, Livio, Del Principe, Mi, Offidani, M, Venditti, Adriano, Ballanti, S, Delia, M, Decembrino, N, Farina, Francesca, Manetta, S, Venditti, A, Offidani, Massimo, Manetta, Sara, Farina, F, Melillo, Lorella, Orciulo, Enrico, Potenza, L, Nadali, G, Marchesi, Francesco, Dragonetti, Giulia, Candoni, A, Castagnola, Carlo, Busca, A, Delia, Mario, Castagnola, C, Orciulo, E, Ballanti, Stelvio, Pagano, L, Busca, Alessandro, Tumbarello, Mario, Nadali, Gianpaolo, Cattaneo, Chiara, Cattaneo, C, Verga, Luisa, Aversa, Franco, Dragonetti, G, Decembrino, Nunzia, Fanci, Rosa   +47 more
core   +1 more source

Combined effects of canola plant density and insecticide management strategies on flea beetle abundance, canola defoliation, and yield across the Canadian prairies

Pest Management Science, EarlyView.
Increasing canola plant density reduced flea beetle abundance per plant and increased yield, independent of region or insecticide use, highlighting its potential as a component of integrated pest management. Abstract The crucifer flea beetle, Phyllotreta cruciferae (Goeze), and the striped flea beetle, Phyllotreta striolata (Fabricius) (Coleoptera ...
Shayla Woodland, Héctor A Cárcamo, Tyler Wist, Jennifer Otani, John Gavloski, Rob W Duncan, Tharshinidevy Nagalingam, Alejandro C Costamagna   +7 more
wiley   +1 more source

Infection risk in rheumatoid arthritis patients treated with biologic and targeted therapies

Rheumatology &Autoimmunity, EarlyView.
In this context, infections associated with each biologic and targeted drug are summarized to inform the stratification of RA patients, including the characteristics of the susceptible patients and their concomitant therapy. We aim to provide a benefit‐risk analysis for clinical decision, and vital indications for the prevention of highly correlated ...
Lujing Wang, Jieshi Lin, Jie Qian
wiley   +1 more source

Universal antifungal prophylaxis effectively prevents fungal bloodstream infection in pediatric liver transplant recipients: a retrospective real-world study

International Journal of Infectious Diseases
Objectives: Fungal bloodstream infection (fBSI) following pediatric liver transplantation presents a significant challenge; however, there remains a paucity of guidance regarding antifungal prophylaxis in this population. This study aimed to evaluate the
Weili Wang, Yangyang Wang, Yuntao Zhang, Wei Zhang, Xueli Bai, Qi Zhang, Tingbo Liang   +6 more
doaj   +1 more source

Determination of itraconazole and hydroxyitraconazole in plasma by use of liquid chromatography-tandem mass spectrometry with on-line solid-phase extraction [PDF]

, 2003
In this paper a method for the simultaneous quantification of the anti-fungal drug itraconazole and its co-active metabolite hydroxyitraconazole in plasma employing liquid chromatography tandem-mass spectrometry and automated solid-phase extraction is ...
Spöhrer, Ute, Schiel, Xaver, Vogeser, Michael   +2 more
core   +1 more source

Sporotrichosis in a Renal Transplant Patient: A Rare Case Report with a Review of the Literature

Saudi Journal of Kidney Diseases and Transplantation, 2023
Sporotrichosis is a rare form of subacute and chronic fungal infection in renal transplant recipients caused by the ubiquitous fungus Sporothrix schenckii.
Suman Sethi, Sudhir Mehta, Vikas Makkar
doaj   +1 more source

Myeloablative Busulfan, Fludarabine and Melphalan Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation in Childhood Myeloid Malignancy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
We report our single‐center experience of transplant outcomes with a busulfan, fludarabine and melphalan‐based conditioning regimen for children < 18 years of age. The regimen was shown to be well tolerated and effective for heavily pretreated children with high‐risk myeloid malignancies prior to allogeneic hematopoietic stem cell transplant.
Mayank Dhamija, Fiona Kerr, Hazel Gough, Johnathan Soggee, Laurence C. Cheung, Rishi S. Kotecha, Shanti Ramachandran   +6 more
wiley   +1 more source

Antifungal Prophylaxis: Why, What and How? [PDF]

Future Microbiology, 2015
41st Annual Meeting of the European Society for Blood and Marrow Transplantation (EBMT 2015), Istanbul, Turkey, 22-25 March 2015 The European Society for Blood and Marrow Transplantation (EBMT) is the leading scientific society for professionals involved in hematopoietic stem-cell transplantation (HSCT) and represents 563 transplant centers from 57 ...
openaire   +2 more sources