Results 351 to 360 of about 3,376,929 (374)

Antifungal Resistance Mechanisms in Dermatophytes

Mycopathologia, 2008
Although fungi do not cause outbreaks or pandemics, the incidence of severe systemic fungal infections has increased significantly, mainly because of the explosive growth in the number of patients with compromised immune system. Thus, drug resistance in pathogenic fungi, including dermatophytes, is gaining importance.
Nilce M, Martinez-Rossi, Nalu T A, Peres, Antonio, Rossi   +2 more
openaire   +2 more sources

Antifungal Drugs and Resistance

1995
From the late 1950’s, extending for two decades thereafter, amphotericin B was the only broad spectrum antifungal drug which could be systemically administered. Because it was the only option, and because systemic mycoses were relatively infrequent, there was little interest in understanding the mechanism of action of amphotericin B, or expanding ...
openaire   +2 more sources

Outwitting Multidrug Resistance to Antifungals

Science, 2008
The economic cost of fungal infection and its mortality associated with multidrug resistance remain unacceptably high. Recent understanding of the transcriptional regulation of plasma membrane efflux pumps of modest specificity provides new avenues for the development of broad-spectrum fungicides.
Brian C, Monk, Andre, Goffeau
openaire   +2 more sources

Body heat drives antifungal resistance

Nature Microbiology
Multi-drug resistance and virulence in Rhodosporidiobolus fluvialis, an emergent human fungal pathogen that causes fungaemia, is driven by body-temperature-induced elevated mutation rates.
Michael J. Bottery, David W. Denning
openaire   +3 more sources

C. albicans biofilms: antifungal resistance, immune evasion, and emerging therapeutic strategies.

International Journal of Antimicrobial Agents, 2022
Fangmei Fan, Yi Liu, Yiqing Liu, Ruixue Lv, Wei Sun, Wenjing Ding, Yanxing Cai, WeiWei Li, Xing Liu, W. Qu   +9 more
semanticscholar   +1 more source

CLINICAL RELEVANCE OF ANTIFUNGAL RESISTANCE

Infectious Disease Clinics of North America, 1997
The availability of standard guidelines (NCCLS M27 document) for antifungal susceptibility testing has facilitated the establishment of tentative interpretive breakpoints for fluconazole and itraconazole by the NCCLS. Based on correlations of MIC values with the outcomes of patients with mostly Candida infections, fluconazole MICs of > or = 64 and ...
openaire   +2 more sources

Antifungal resistance

2020
Indranil Samanta, Samiran Bandyopadhyay
openaire   +1 more source

Evolution of antifungal resistance in the environment

Nature Microbiology
N. van Rhijn, J. Rhodes
semanticscholar   +1 more source

Expert Panel Review of Skin and Hair Dermatophytoses in an Era of Antifungal Resistance

American Journal of Clinical Dermatology
R. Hill, A. Caplan, Boni E Elewski, J. A. Gold, Shawn R. Lockhart, Dallas J. Smith, S. Lipner   +6 more
semanticscholar   +1 more source

The effect of biosynthesized selenium nanoparticles on the expression of CYP51A and HSP90 antifungal resistance genes in Aspergillus fumigatus and Aspergillus flavus

Biotechnology progress (Print), 2021
Mahdi Hosseini Bafghi, R. Nazari, M. Darroudi, M. Zargar, H. Zarrinfar   +4 more
semanticscholar   +1 more source