Results 211 to 220 of about 58,806 (288)

The dysregulation of innate immunity by Porphyromonas gingivalis in the etiology of Alzheimer's disease

Journal of Internal Medicine, EarlyView.
Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron, Jennifer S. Lin, Mark I. Ryder, Peter Bergman   +3 more
wiley   +1 more source

A conserved C2H2 zinc finger protein, Rel1, links ribosome biogenesis to sexual development and antifungal susceptibility in a ubiquitous human fungal pathogen. [PDF]

Appl Environ Microbiol
Yan L, Chen M, Liu Y, Hu P, Wang Y, Cao Y, Huang Y, Tian X, Xu X, Zheng F.   +9 more
europepmc   +1 more source

Influence of nanohydroxyapatite mouthwash on the growth of Candida albicans biofilm on milled denture surfaces: An in vitro study

Journal of Prosthodontics, EarlyView.
Abstract Purpose There is a need for effective solutions for the persistent prevalence of denture stomatitis (DS) in denture‐wearing populations. This study assessed the impact of nanohydroxyapatite (nanoHAP) nanoparticles on Candida albicans biofilm formation on milled polymethylmethacrylate (PMMA) denture bases.
Cynthia U. Udeh, Bennett T. Amaechi, Parveez A. Abdul‐Azees, Amos C. Obiefuna, Chun‐Yen Lin, Nahid IftiKhar, Sunil Mankar, Temitope O. Omosebi, Tejal Gohil   +8 more
wiley   +1 more source

The prevalence and antifungal susceptibility profile of <i>Candida dubliniensis</i> and <i>Candida albicans</i> in the respiratory tract of patients with cystic fibrosis. [PDF]

Microbiol Spectr
Krantz E, Jönsson B, Gilljam M, Lindblad A, Abedzadeh B, Karlsson R, Kondori N.   +6 more
europepmc   +1 more source

Diversity of phenotypically non-dermatophyte, non-Aspergillus filamentous fungi causing nail infections: importance of accurate identification and antifungal susceptibility testing

, 2019
Chi‐Ching Tsang, James Y. M. Tang, Ka‐Fai Chan, Chun‐Yi Lee, Jasper Fuk‐Woo Chan, Antonio H. Y. Ngan, Mei Cheung, Eunice C. L. Lau, Xin Li, Ricky H. Y. Ng, Christopher K.C. Lai, Kitty S. C. Fung, Susanna K. P. Lau, Patrick C. Y. Woo   +13 more
openalex   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Elevated carbon dioxide enhances the growth and reduces the antifungal susceptibility of <i>Histoplasma capsulatum</i>. [PDF]

Microbiol Spectr
Shen Q, Steinmetz K.
europepmc   +1 more source

Teledermatology Exposes a Neglected Endemic: The Hidden Burden of Tinea Imbricata in Eastern Indonesia

International Journal of Dermatology, EarlyView.
Livia Ayuni, Maria Harianja, Messe R. Ataupah, Ruth D. Laiskodat, Jochem Buil, Claus Bøgh, Hardyanto Soebono, Marlous L. Grijsen   +7 more
wiley   +1 more source

Time Kill Curve PD Modelling Experiments Are Affected by Trailing MIC Endpoints: Refinement of MIC Determination for S. pseudintermedius

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Trailing endpoints are a recognised challenge in broth microdilution MIC testing, particularly for bacteriostatic agents such as trimethoprim (TMP) and sulphonamides. In this study, we applied a pharmacodynamically guided refinement to determine the MIC of the combination against Staphylococcus pseudintermedius; we did not aim at redefining ...
Andrew Mead, Ludovic Pelligand
wiley   +1 more source

Prevalence and antifungal susceptibility profiles of <i>Candida</i> isolates among patients with candiduria: a multiplex PCR assay. [PDF]

Curr Med Mycol
Darabian S, Pakravan S, Jozpanahi M, Karami A, Amanloo S, Morovati H.   +5 more
europepmc   +1 more source